Results 81 to 90 of about 606,469 (298)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

OP 4.1 Viral persistence and NK cells

open access: yesJournal of Virus Eradication, 2022
Michaela Müller-Trutwin
doaj   +1 more source

ATIVIDADE RESIDUAL DE IMAZAQUIN E ALACHLOR+ATRAZINE PARA PLANTIO SEQÜENCIAL DE CANOLA CARRYOVER OF IMAZAQUIN AND ALACHLOR+ATRAZINE TO THE SUCCESSIONAL CANOLA CROP

open access: yesCiência Rural, 2001
No presente trabalho, avaliou-se o efeito residual dos herbicidas imazaquin (150 e 300g de equivalente ácido ha-1) e alachlor+atrazine (1430+1430 e 2860+2860g ha-1), aplicados respectivamente em soja e milho, visando a determinar o intervalo de tempo ...
Rubem Silvério de Oliveira Júnior
doaj   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

OP 2.6 – 00135 Constitutive NKG2A levels and timing of antiretroviral therapy initiation impact the potential role of NK cells after treatment interruption - the pVISCONTI study

open access: yesJournal of Virus Eradication, 2022
A. Chapel   +13 more
doaj   +1 more source

Degradation dynamics of quinalphos on cabbage under subtropical conditions of Ludhiana, Punjab, India

open access: yesOrbital: The Electronic Journal of Chemistry, 2011
A study was undertaken to determine the disappearance trends of quinalphos residues on cabbage under subtropical conditions at Ludhiana. Single application of quinalphos was made @ 500 and 1000 g a.i.
Gurminder Singh Chahil   +5 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

The Evolving Military Learner Population: A Review of the Literature

open access: yesOnline Learning, 2014
This literature review examines the evolving online military learner population with emphasis on current generation military learners, who are most frequently Post-9/11 veterans.
Kate Ford, Karen Vignare
doaj   +1 more source

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