Results 101 to 110 of about 11,052,815 (324)
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Theory and Practice of Data Citation
, 2017 Citations are the cornerstone of knowledge propagation and the primary means of assessing the quality of research, as well as directing investments in science.
Silvello, Gianmaria
core +1 more source
Power and Persistent Identifiers
, 2018 Persistent identifiers are critical components of modern and evolving data infrastructure. Like much of the mechanics of civilization, PIDs are based on trusted registries. The operation of these registries can have significant power over how and when data are shared.
, Parsons, , Fox
openaire +1 more source
Persistent Identifier Services For The Humanities
, 2017 This presentation describes the outcomes of the Humanities workshop held at the British Library and the challenges of using Persistent Identifier services for the Humanities.
Dappert, Angela +3 more
openaire +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
ARDC's persistent identifier (PID) services
, 2021 This presentation was part of an “Orientation to ARDC services and expertise” series, specifically aimed at people involved in one of the ARDC co-investment projects commencing early 2021. In addition to co-investment of money, ARDC contributes expertise and services in a range of areas: research vocabularies, persistent identifiers, data discovery ...
Simons, Natasha +2 more
openaire +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
A Model for Using DataCite DOIs in Observatory Bibliographies
EPJ Web of Conferences, 2018 The use of DOI persistent identifiers has become an attractive mechanism for citing datasets in articles. However, taking the users’ interests into account requires careful consideration of the way in which we apply these identifiers.
Rots Arnold +2 more
doaj +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source