Results 111 to 120 of about 11,052,815 (324)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Analysis of PPI networks of transcriptomic expression identifies hub genes associated with Newcastle disease virus persistent infection in bladder cancer [PDF]

, 2022
Umar Ahmad, Syahril Abdullah, De Ming Chau, Suet Lin Chia, Khatijah Yusoff, Soon Choy Chan, Teng Aik Ong, Azad Hassan Abdul Razack, Abhi Veerakumarasivam   +8 more
openalex   +1 more source

Persistent Identifiers for Heritage Collections

, 2020
Slides for lightning talk about UKRI funded project on persistent identifiers for heritage collections due to begin in early 2020.
Madden, Frances, Kotarski, Rachael
openaire   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Persistent Identifiers: the ‘URN Granular’ Project of the German National Library and the University and State Library Halle

Liber Quarterly: The Journal of European Research Libraries, 2010
This paper describes a project carried out by the German National Library, the University and State Library Sachsen-Anhalt in Halle and Semantics GmbH Aachen to establish routines of persistent identification for individual pages of web publications in ...
Dorothea Sommer
doaj   +1 more source

Finite Mixture Models Based on Pain Intensity, Functional Disability and Psychological Distress Composite Assessment Allow to Identify Two Distinct Classes of Persistent Spinal Pain Syndrome after Surgery Patients Related to Their Quality of Life

, 2021
Amine Ounajim, Maxime Billot, Pierre‐Yves Louis, Yousri Slaoui, Denis Frasca, Lisa Goudman, Manuel Roulaud, Nicolas Naïditch, Bertille Lorgeoux, Sandrine Baron, Kévin Nivole, Mathilde Many, Nihel Adjali, Philippe Page, Bénédicte Bouche, Elodie Charrier, Laure Poupin, Delphine Rannou, Géraldine Brumauld de Montgazon, Brigitte Roy-Moreau, Chantal Wood, Raphaël Rigoard, Romain David, Maarten Moens, Philippe Rigoard   +24 more
openalex   +2 more sources

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Evaluation of different ways to identify persistent positivity of lupus anticoagulant in systemic lupus erythematosus [PDF]

, 2020
Michelle Petri, Mertcan Avci, Laurence S. Magder   +2 more
openalex   +1 more source

Symmetric Replication for Structured Peer-to-Peer Systems [PDF]

, 2005
Structured peer-to-peer systems rely on replication as a basic means to provide fault-tolerance in presence of high churn. Most select replicas using either multiple hash functions, successor-lists, or leaf-sets.
Ghodsi, Ali, Haridi, Seif, Onana Alima, Luc   +2 more
core   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source