Results 11 to 20 of about 13,159 (299)
High Persister Mutants in Mycobacterium tuberculosis. [PDF]
PLoS ONE, 2016 Mycobacterium tuberculosis forms drug-tolerant persister cells that are the probable cause of its recalcitrance to antibiotic therapy. While genetically identical to the rest of the population, persisters are dormant, which protects them from killing by ...
Heather L Torrey +4 more
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Heterogeneous persister cells formation in Acinetobacter baumannii. [PDF]
PLoS ONE, 2013 Bacterial persistence is a feature that allows susceptible bacteria to survive extreme concentrations of antibiotics and it has been verified in a number of species, such as Escherichia coli, Pseudomonas aeruginosa, Staphylococcus spp., Mycobacterium spp.
Valdir Cristóvão Barth +6 more
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Persister control by leveraging dormancy associated reduction of antibiotic efflux.
PLoS Pathogens, 2021 Persistent bacterial infections do not respond to current antibiotic treatments and thus present a great medical challenge. These conditions have been linked to the formation of dormant subpopulations of bacteria, known as persister cells, that are ...
Sweta Roy +5 more
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Combatting persister cells: The daunting task in post-antibiotics era
Cell Insight, 2023 Over the years, much attention has been drawn to antibiotic resistance bacteria, but drug inefficacy caused by a subgroup of special phenotypic variants – persisters – has been largely neglected in both scientific and clinical field.
Yidan Zhou +3 more
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ATP-Dependent Persister Formation in
mBio, 2017 Persisters are dormant variants that form a subpopulation of cells tolerant to antibiotics. Persisters are largely responsible for the recalcitrance of chronic infections to therapy.
Yue Shan +5 more
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Graded Persistence Diagrams and Persistence Landscapes [PDF]
Discrete & Computational Geometry, 2021 We introduce a refinement of the persistence diagram, the graded persistence diagram. It is the Mobius inversion of the graded rank function, which is obtained from the rank function using the unary numeral system. Both persistence diagrams and graded persistence diagrams are integer-valued functions on the Cartesian plane.
Leo Betthauser +2 more
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Is persistent memory persistent? [PDF]
Communications of the ACM, 2020 A simple and inexpensive test of failure-atomic update mechanisms.
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Persistence and anti-persistence in treadmill walking [PDF]
Gait & Posture, 2021 Abstract Background Long-range persistent correlations in stride time (ST) and length (SL) are the fundamental traits of treadmill gait. Our recent work showed that the ST and SL time series’ statistical properties originated from the superposition of large-scale trends and small-scale fluctuations ...
Klaudia Kozlowska +2 more
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Reverting antibiotic tolerance of Pseudomonas aeruginosa PAO1 persister cells by (Z)-4-bromo-5-(bromomethylene)-3-methylfuran-2(5H)-one. [PDF]
PLoS ONE, 2012 BACKGROUND: Bacteria are well known to form dormant persister cells that are tolerant to most antibiotics. Such intrinsic tolerance also facilitates the development of multidrug resistance through acquired mechanisms. Thus persister cells are a promising
Jiachuan Pan +3 more
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Frontiers in Microbiology, 2021 Background: Persisters are important reasons for persistent infections, and they can lead to antibiotic treatment failure in patients and consequently chronic infection.
Xuyang Wang +8 more
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