Results 21 to 30 of about 13,159 (299)

Phenol-Soluble Modulins Modulate Persister Cell Formation in Staphylococcus aureus

open access: yesFrontiers in Microbiology, 2020
Staphylococcus aureus is a human pathogen that can cause chronic and recurrent infections and is recalcitrant to antibiotic chemotherapy. This trait is partly attributed to its ability to form persister cells, which are subpopulations of cells that are ...
Mara Baldry   +6 more
doaj   +1 more source

ColE-type plasmid bearing blaOXA-232 increases persister cell formation

open access: yesJournal of Global Antimicrobial Resistance, 2023
Objectives: Bacterial persister cells are a sub-population of cells that are tolerant to high concentrations of antibiotics. In this study, we investigated the effect of plasmids bearing carbapenemase genes on persister cell formation.
Yun Young Cho, Kwan Soo Ko
doaj   +1 more source

Persistent Pandemics

open access: yesEconomics & Human Biology, 2021
We ask whether mortality from historical pandemics has any predictive content for mortality in the Covid-19 pandemic. We find strong persistence in public health performance. Places that performed worse in terms of mortality in the 1918 influenza pandemic also have higher Covid-19 mortality today.
Peter Z. Lin, Christopher M. Meissner
openaire   +5 more sources

Glutathione Peroxidase 4 as a Therapeutic Target for Anti-Colorectal Cancer Drug-Tolerant Persister Cells

open access: yesFrontiers in Oncology, 2022
BackgroundDespite the effectiveness of chemotherapy and targeted therapy for colorectal cancer, drug resistance drives therapy failure and tumor relapse.
Xiaoli Zhang   +8 more
doaj   +1 more source

Bacterial drug tolerance under clinical conditions is governed by anaerobic adaptation but not anaerobic respiration [PDF]

open access: yes, 2014
Non-inherited antibiotic resistance is a phenomenon whereby a subpopulation of genetically identical bacteria displays phenotypic tolerance to antibiotics. We show that, compared to E. coli, the clinically relevant genus Burkholderia displays much higher
Butler, Clive S.   +5 more
core   +1 more source

Zigzag Persistence [PDF]

open access: yesFoundations of Computational Mathematics, 2010
We describe a new methodology for studying persistence of topological features across a family of spaces or point-cloud data sets, called zigzag persistence. Building on classical results about quiver representations, zigzag persistence generalises the highly successful theory of persistent homology and addresses several situations which are not ...
Gunnar E. Carlsson, Vin de Silva
openaire   +3 more sources

High-Throughput Screening of a Promoter Library Reveals New Persister Mechanisms in Escherichia Coli

open access: yesMicrobiology Spectrum, 2022
Persister cells are a small subpopulation of phenotypic variants that survive high concentrations of bactericidal antibiotics. Their survival mechanisms are not heritable and can be formed stochastically or triggered by environmental stresses such as ...
Sayed Golam Mohiuddin   +2 more
doaj   +1 more source

Survey on phenotypic resistance in Enterococcus faecalis: comparison between the expression of biofilm-associated genes in Enterococcus faecalis persister and non-persister cells

open access: yes, 2022
Background Phenotypic resistance is considered as a serious therapeutic challenge for which a definitive remedy has not been discovered yet. Biofilm and persister cell formation are two well-studied phenotypic resistance phenomena, leading to the ...
Maleki, A.   +6 more
core   +2 more sources

Selection of the Amino Acid and Saccharide That Increase the Tetracycline Susceptibility of Vibrio splendidus

open access: yesFrontiers in Veterinary Science, 2022
Bacterial persister cells are a subpopulation of isogenic bacteria with characteristics of reduced metabolic activity and multidrug antibiotic resistance.
Guohua Jiang   +10 more
doaj   +1 more source

PERSISTENCE IN CONVERGENCE [PDF]

open access: yesMacroeconomic Dynamics, 2013
In this paper, we examine the convergence hypothesis using a long memory framework that allows for structural breaks and does not rely on a benchmark country. We find that even though the long memory framework of analysis is much richer than the simple I(1)/I(0) alternative, a simple absolute divergence and rapid convergence dichotomy produced by the ...
Thanasis Stengos, M. Ege Yazgan
openaire   +3 more sources

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