Results 11 to 20 of about 8,611 (241)
Immune Response Modulation by Pseudomonas aeruginosa Persister Cells
mBio, 2023 Bacterial persister cells—a metabolically dormant subpopulation tolerant to antimicrobials—contribute to chronic infections and are thought to evade host immunity.
Cody James Hastings +3 more
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In VitroStudies of Persister Cells [PDF]
Microbiology and Molecular Biology Reviews, 2020 Many bacterial pathogens can permanently colonize their host and establish either chronic or recurrent infections that the immune system and antimicrobial therapies fail to eradicate. Antibiotic persisters (persister cells) are believed to be among the factors that make these infections challenging.
Kaldalu, Niilo +5 more
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Reverting antibiotic tolerance of Pseudomonas aeruginosa PAO1 persister cells by (Z)-4-bromo-5-(bromomethylene)-3-methylfuran-2(5H)-one. [PDF]
PLoS ONE, 2012 BACKGROUND: Bacteria are well known to form dormant persister cells that are tolerant to most antibiotics. Such intrinsic tolerance also facilitates the development of multidrug resistance through acquired mechanisms. Thus persister cells are a promising
Jiachuan Pan +3 more
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Frontiers in Oncology, 2022 BackgroundDespite the effectiveness of chemotherapy and targeted therapy for colorectal cancer, drug resistance drives therapy failure and tumor relapse.
Xiaoli Zhang +8 more
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Frontiers in Cellular and Infection Microbiology, 2020 Persister cells are difficult to eliminate because they are tolerant to antibiotic stress. In the present study, using artificially induced Escherichia coli persister cells, we found that reactive oxygen species (ROS) have greater effects on persister ...
Aki Kawano +6 more
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A Transient Metabolic State in Melanoma Persister Cells Mediated by Chemotherapeutic Treatments
Frontiers in Molecular Biosciences, 2022 Persistence is a transient state that poses an important health concern in cancer therapy. The mechanisms associated with persister phenotypes are highly diverse and complex, and many aspects of persister cell physiology remain to be explored. We applied
Prashant Karki +3 more
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Persister cells and tolerance to antimicrobials [PDF]
FEMS Microbiology Letters, 2004 Bacterial populations produce persister cells that neither grow nor die in the presence of microbicidal antibiotics. Persisters are largely responsible for high levels of biofilm tolerance to antimicrobials, but virtually nothing was known about their biology.
Iris, Keren +4 more
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Copper Kills Escherichia coli Persister Cells
Antibiotics, 2020 Due to their reduced metabolism, persister cells can survive most antimicrobial treatments, which usually rely on corrupting active biochemical pathways.
Paula Maria Moreira Martins +3 more
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Frontiers in Veterinary Science, 2022 Bacterial persister cells are a subpopulation of isogenic bacteria with characteristics of reduced metabolic activity and multidrug antibiotic resistance.
Guohua Jiang +10 more
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Bacterial persister cells tackled [PDF]
Nature, 2018 Chronic infections can be hard to treat because slow-growing bacteria known as persister cells are usually unharmed by antibiotics. The identification of molecules that target such cells might provide a solution. Chronic infections can be hard to treat because slow-growing bacteria known as persister cells are usually unharmed by antibiotics.
Julian G, Hurdle, Aditi, Deshpande
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