Results 241 to 250 of about 4,772,205 (283)

TCA cycle mode switch determines the fate of pirtobrutinib-tolerant persister cells in mantle cell lymphoma.

Blood
Wang W, Cai Q, Liu Y, Nie L, Lee HH, Yan F, Fei Y, Yao Y, Li Y, Tan L, Lorenzi PL, Wang YN, Yao J, Chen Z, McIntosh JM, Yu CT, Jain P, Jiang VC, Vargas J, Li X, Zhang T, Li S, Santos D, Thirumurthi S, Seeley EH, Simon LM, Flowers C, Ok CY, Wang M.   +28 more
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The Activity of EGFR CAR NK and CAR T Cells against EGFR Inhibitor-Resistant NSCLC and Drug-Tolerant Persister Cells. [PDF]

Clin Cancer Res
Yang Y, Nilsson MB, Yu X, Poteete A, Jiang H, Huang Q, He J, Heeke S, Heymach JV.   +8 more
europepmc   +1 more source

Targeting yes-associated protein to overcome imatinib resistance in gastrointestinal stromal tumor drug-tolerant persister cells. [PDF]

Gastric Cancer
Yokouchi T, Takahashi T, Nishida T, Tanaka K, Kurokawa Y, Yamamoto K, Saito T, Hagi T, Momose K, Yamashita K, Makino T, Kawai K, Serada S, Fujimoto M, Hirota S, Nakajima K, Naka T, Eguchi H, Doki Y.   +18 more
europepmc   +1 more source

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Persistent Bacterial Infections and Persister Cells

Nature Reviews Microbiology, 2017
Many bacteria can infect and persist inside their hosts for long periods of time. This can be due to immunosuppression of the host, immune evasion by the pathogen and/or ineffective killing by antibiotics. Bacteria can survive antibiotic treatment if they are resistant or tolerant to a drug.
Robert A Fisher, Sophie Helaine
exaly   +4 more sources

Drug-Tolerant Persister Cancer Cells Are Vulnerable to GPX4 Inhibition [PDF]

Nature, 2017
Cancer persister cells, which survive cytotoxic treatments, are shown to be sensitive to inhibition of the lipid hydroperoxidase ...
Vasanthi S Viswanathan, Matthew J Ryan, Michael E Berens   +2 more
exaly   +2 more sources

Cycling persister cells

Nature Reviews Cancer, 2021
Oren et al. developed a lentiviral barcode library, called Watermelon, to characterize the rare population of cycling persister cancer cells that arise during the course of drug treatment and promote tumour relapse.
openaire   +2 more sources

Comparison of Starvation-Induced Persister Cells with Antibiotic-Induced Persister Cells

Current Microbiology, 2019
The phenotypic heterogeneity in a large population arises because of fluctuation in microenvironments and stochastic gene expressions. In this report, we isolated two types of persistent sub-populations of Vibrio cholerae, one triggered by starvation and another by antibiotics.
Shridhar S, Paranjape, Ravindranath, Shashidhar   +1 more
openaire   +2 more sources

The persistence of T cell memory

Cellular and Molecular Life Sciences, 2010
T cell memory is a crucial feature of the adaptive immune system in the defense against pathogens. During the last years, numerous studies have focused their efforts on uncovering the signals, inflammatory cues, and extracellular factors that support memory differentiation.
Mark A, Daniels, Emma, Teixeiro
openaire   +2 more sources