Results 251 to 260 of about 4,772,205 (283)
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Memory B-cell persistence is independent of persisting immunizing antigen
Nature, 2000Immunological memory in the antibody system is generated in T-cell-dependent responses and carried by long-lived memory B cells that recognize antigen by high-affinity antibodies. But it remains controversial whether these B cells represent true 'memory' cells (that is, their maintenance is independent of the immunizing antigen), or whether they are a ...
Maruyama, M., Lam, K.-P., Rajewsky, K.
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Combatting bacterial persister cells
Biotechnology and Bioengineering, 2015ABSTRACTMost bacterial cells lead lives of quiet desperation in biofilms, combatting stress; yet, their prevalence attests to their ability to alter gene regulation to cope with myriad insults. Since biofilm bacteria are faced with starvation and other environmental stress (e.g., antibiotics from competitors, oxidative stress from host immune systems),
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PERSISTENCE OF BLOOD CELLS IN URINE
Acta Medica Scandinavica, 1968Abstract In clinical work the stability of blood cells in urine is a point of practical importance. Provided bacterial contamination can be avoided, erythrocytes and leucocytes are well preserved in acidic urine of a specific gravity higher than 1.008‐1.011 for at least 24 hours. Whether sterile specimens are kept at room temperature, in a refrigerator,
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Nucleolar persistence in embryonal carcinoma cells
Experimental Cell Research, 1981Abstract A series of embryonal carcinoma (EC) lines were found to have nucleoli which persisted through metaphase and anaphase in 60–88% of cells. When these cells differentiated, either spontaneously or upon chemical induction with retinoic acid or dimethylacetamide, the level of nucleolar persistence dropped to under 20%.
Sheldon, S, Speers, W C, Lehman, J M
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Phenomenological Approach to Cancer Cell Persistence
Physical Review Letters, 2022Drug persistence is a phenomenon by which a small percentage of cancer cells survive the presentation of targeted therapy by transitioning to a quiescent state. Eventually some of these persister cells can transition back to an active growing state and give rise to resistant tumors.
David A. Kessler, Herbert Levine
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PERSISTENT POLYCLONAL B-CELL LYMPHOCYTOSIS
Acta Clinica Belgica, 2002We present a case of persistent polyclonal B-cell lymphocytosis (PPBL). This syndrome is characterized by a persistent lymphocytosis with circulating atypical binucleated lymphocytes. The patient had serological evidence of a previous EBV infection, had raised polyclonal serum IgM levels and was a heavy smoker. No malignancy was detected.
L, Ide +7 more
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A Persistent Lymphoid Cell Population in the Thymus
Nature New Biology, 1973The mouse thymus contains cells which, when teased out of the organ, have various described properties. A proportion of them can respond in vitro to phytohaemagglutinin (PHA)1; whole thymocyte populations transferred into irradiated adult or neonatally thymectomized mice confer some restoration of immunological competence2; thymocytes can be activated ...
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Persistent polyclonal B-cell lymphocytosis
Leukemia Research, 1994We document a case of persistent lymphocytosis in which the characteristic binucleated circulating lymphocytes were shown immunologically to be polyclonal B-cells. Cytogenetic and molecular studies failed to show a clonal population. A review of the literature on this rare condition, persistent polyclonal B-cell lymphocytosis, highlights an association
S, Agrawal +5 more
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Persistent infections “interfere” with B cells
Science, 2016Infectious Diseases Certain pathogens, including HIV, hepatitis virus, and lymphocytic choriomeningitis virus (LCMV), cause persistent infections that are often associated with suboptimal antibody responses. Fallet et al. , Moseman et al. , and Sammicheli et al.
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Multidrug Tolerance of Biofilms and Persister Cells
Current Topics in Microbiology and Immunology, 2008Bacterial populations produce a small number of dormant persister cells that exhibit multidrug tolerance. All resistance mechanisms do essentially the same thing: prevent the antibiotic from hitting a target. By contrast, tolerance apparently works by shutting down the targets.
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