Results 71 to 80 of about 4,772,205 (283)

Characterizing Z-rings in Persister Cells

, 2023
Persister cells are a subpopulation of bacterial cells that survive antibiotic treatments without specialized mechanisms by temporarily entering a dormant state [1].
Ofomaja, Miracle
core  

Persister and non-persister cells and their respective descendants through time considering τ0 = 30, k1 = 0.1, k2 = 0.01.

, 2021
Results of simulations when we assumed that the persister population decays according to an exponential and that persister cells leave the dormant state as soon as the medium becomes detoxified. (DOCX)
Teresa Nogueira (118513), João S. Rebelo (11378420), Francisco Dionisio (185482), Francisca Monteiro (3196734), Célia P. F. Domingues (11378423)   +4 more
core   +1 more source

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh, Susmita Sarangi, Caileigh Pudela, Catherine M. Broome, Tara K. Suntum   +4 more
wiley   +1 more source

Integrating multi-omics data with network modeling to characterize Pseudomonas aeruginosa persister cell metabolism

Journal of Bacteriology
Pseudomonas aeruginosa is a gram-negative bacterial pathogen capable of forming antimicrobial-tolerant subpopulations known as persister cells. These cells are transient phenotypic variants that can tolerate antimicrobial treatment and have been ...
Joseph M. Ficarrotta, Anna S. Blazier, Aline Metris, Sidney L. Rhodes, Glynis L. Kolling, Jason A. Papin   +5 more
doaj   +1 more source

Flow-cytometry analysis reveals persister resuscitation characteristics

BMC Microbiology, 2020
Background Persisters and viable but non-culturable (VBNC) cells are two phenotypic variants known to be highly tolerant to antibiotics. Although both cell types are stained as live and often appear as nongrowing during antibiotic treatment, the only ...
Sayed Golam Mohiuddin, Pouria Kavousi, Mehmet A. Orman   +2 more
doaj   +1 more source

Viable But Non-Culturable Cells Are Persister Cells

, 2017
Bacteria have two dormant phenotypes: the viable but non-culturable (VBNC) state and the persister state. Both resting stages arise without mutation and both have been linked to chronic infections; however, persister cells revive rapidly whereas the cell
Thomas K. Wood, Jun-Seob Kim, Nityananda Chowdhury   +2 more
core   +1 more source

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba, Shweta Bansal, Tea Reljic, Allyne Montecillo‐Aguelo, Hamidah Alias, Farrah Amaranto, Maria Stella Aquino‐Calingasan, Bambang Ardianto, Eggi Arguni, Sally Blair, Thi Tam Dang, Maria Beatriz Gepte, Samanmalee Gunasekara, Andini Handayani, Miriam Kimpo, Catherine G. Lam, Nawachai Lertvivatpong, Sergio Licona, Ana Loseo, Ratha Mlis, Vivian Moreno Berrio, Nguyen Hoai Anh, Anna Lisa Ong‐Lim, Ha Thu Pham, Krishna Sagar Sharma, Bun Sereyleak, Sally Jane G. Velasco‐Aro, Su Yadana, Ambuj Kumar, Sheena Mukkada   +29 more
wiley   +1 more source

Fungal persister cells: The basis for recalcitrant infections? [PDF]

PLoS Pathogens, 2018
Persister cells are a small subpopulation within fungal biofilms that are highly resistant to high concentrations of antifungals and therefore most likely contribute to the resistance and recalcitrance of biofilm infections.
Jurgen Wuyts, Patrick Van Dijck, Michelle Holtappels   +2 more
doaj   +1 more source

Neurocognitive, School‐Based, and Quality of Life Outcomes for Youth With Sickle Cell Disease and Thalassemia: A Scoping Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling, Hakim Tokhi, Alexander A. Boucher   +2 more
wiley   +1 more source

Bacterial Persister Cells: Mechanisms of Formation, Control, and Eradication

, 2023
Bacterial Persister Cells (BPCs) are quiescent, slow-growing or growth-arrested phenotypic variants of normal bacterial cells that are transiently tolerant to antibiotics.
Kouhsari, E., Mohammad Sholeh, Mirbalouchzehi, A., Sholeh, M., Kaviar, V. H., Sajad Yaghoubi, Ali Mirbalouchzehi, Asadi, A., Ahmadi, A., Yaghoubi, S., Vahab Hassan Kaviar, Abdi, M., Milad Abdi, Ebrahim Kouhsari, Alireza Ahmadi, Arezoo Asadi   +15 more
core   +1 more source