Results 41 to 50 of about 58,109 (252)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

The Relationship Between Individual Personality Characteristics and Person-Job Fit Among Primary and Secondary School Teachers in New Zealand

open access: yes, 2012
Research has shown that individual personality characteristics are strongly related to an employee’s affective and behavioural responses to the job and/or workplace (Barrick & Mount, 1991; Judge & Bono, 2001, Kumar & Bakhshi, 2010).
Chan, Jing Yi (Daphne)
core  

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Uncertainty Management’s Impact on Job Satisfaction and Innovation [PDF]

open access: yes
Purpose – The purpose of this paper is to examine the relationships between person-organization uncertainty management (UM) fit, and two outcomes in an innovative workplace: job satisfaction and innovation.
Mihai BOCARNEA, Michael LANE
core  

Socio-demographic predictors of person–organization fit

open access: yes, 2017
Objectives: The aim of this study was to explore the relationship between socio-demographic characteristics and the level of complementary and supplementary person–organization fit (P–O fit).
Dorota Merecz-Kot   +3 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Pengaruh Person Organization Fit Dan Person Job Fit Terhadap Job Satisfaction Pegawai BPR Duta Artha Sejahtera

open access: yes
This study was conducted to describe the influence of Person-Organization Fit and Person-Job Fit on Job Satisfaction among employees of BPR Duta Artha Sejahtera.
Suratman, Maman   +1 more
core   +1 more source

Longitudinal reciprocal relationships between core self-evaluations and job satisfaction [PDF]

open access: yes, 2011
This study aims to understand change in core self-evaluations by investigating dynamics of CSE and life experiences as indicated by job satisfaction with a multilevel perspective in terms of within- and between-individual change.
Wu, Chiahuei
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

PENGARUH JOB ATTRIBUTE, PERSON-ORGANIZATION FIT, DAN PERSON-JOB FIT TERHADAP KESESUAIAN KARIR DENGAN OPINI LINGKUNGAN PERUSAHAAN SEBAGAI MEDIASI [PDF]

open access: yes, 2015
Penelitian ini termasuk kedalam penelitian pengujian hipotesis guna menguji: 1) pengaruh job attribute pada person-career fit yang dimediasi oleh opinion, 2) pengaruh person-organization fit pada person-career fit yang dimediasi oleh opinion, 3) pengaruh
NARWATI, NOVA YULITA
core  

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