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Evaluation of Immunobiological Properties of Bordetella pertussis Vaccine Strains

open access: diamondБиопрепараты: Профилактика, диагностика, лечение, 2018
The study performed as part of evaluation of immunobiological properties of Bordetella pertussis vaccine strains offered an opportunity to standardize pertussis bacterial mass based on the content of surface antigens — agglutinogens 1, 2 and 3.
I. A. Alekseeva, O. V. Perelygina
doaj   +3 more sources

Evaluating the Relationship Between the Introduction of the Acellular Pertussis Vaccine and Whooping Cough Resurgence in the United States [PDF]

open access: yesVaccines
Background/Objectives: The whole cell pertussis vaccine was introduced in the United States in the 1940s and switched to the acellular pertussis vaccine partially in 1992 and completely in 1997. This study examines the relationship between the resurgence
Jeegan Parikh   +2 more
doaj   +2 more sources

Less reactogenic whole-cell pertussis vaccine confers protection from Bordetella pertussis infection [PDF]

open access: yesmSphere
Pertussis resurged over the last decade in most countries that replaced the traditional whole-cell pertussis vaccines (wP) by the less reactogenic acellular pertussis vaccines (aP).
Karolína Škopová   +6 more
doaj   +2 more sources

Pertussis Vaccine Candidate Based on Outer Membrane Vesicles Derived From Biofilm Culture [PDF]

open access: yesFrontiers in Immunology, 2021
Outer membrane vesicles (OMV) derived from Bordetella pertussis—the etiologic agent of the resurgent disease called pertussis—are safe and effective in preventing bacterial colonization in the lungs of immunized mice.
Francisco Carriquiriborde   +9 more
doaj   +2 more sources

Intranasal Immunization With a c-di-GMP-Adjuvanted Acellular Pertussis Vaccine Provides Superior Immunity Against Bordetella pertussis in a Mouse Model [PDF]

open access: yesFrontiers in Immunology, 2022
Pertussis, caused by the gram-negative bacterium Bordetella pertussis, is a highly contagious respiratory disease. Intranasal vaccination is an ideal strategy to prevent pertussis, as the nasal mucosa represents the first-line barrier to B.
Wenwen Jiang   +9 more
doaj   +2 more sources

Whole-Cell and Acellular Pertussis Vaccine: Reflections on Efficacy. [PDF]

open access: diamondMed Princ Pract, 2022
Alghounaim M   +4 more
europepmc   +3 more sources

A novel vaccine formulation candidate based on lipooligosaccharides and pertussis toxin against Bordetella pertussis

open access: yesFrontiers in Immunology, 2023
Pertussis is a severe human respiratory tract infectious disease caused by Bordetella pertussis that primarily affects infants and young children.
Jingjing Gao   +6 more
doaj   +1 more source

Comparing the pertussis antibody levels of healthy children immunized with four doses of DTap-IPV/Hib (Pentaxim) combination vaccine and DTaP vaccine in Quzhou, China

open access: yesFrontiers in Immunology, 2023
Despite the high coverage of pertussis vaccines in high-income countries, pertussis resurgence has been reported in recent years, and has stimulated interest in the effects of vaccines and vaccination strategies. Immunoglobulin G (IgG) antibodies against
Zhiying Yin   +8 more
doaj   +1 more source

Seroprevalence of Antibodies to Pertussis Toxin among Different Age Groups in Thailand after 37 Years of Universal Whole-Cell Pertussis Vaccination. [PDF]

open access: yesPLoS ONE, 2016
Despite the high coverage of prophylactic vaccine against Bordetella pertussis infection in many countries for more than three decades, pertussis remains a common vaccine-preventable disease. Infections have been detected more commonly in countries using
Nasamon Wanlapakorn   +5 more
doaj   +1 more source

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