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Acellular Pertussis Vaccine Effectiveness Over Time
Pediatrics, 2019 Compared with children fully DTaP vaccinated, unvaccinated and undervaccinated children were at a greater risk of pertussis. However, most pertussis cases occurred among age-appropriately vaccinated children.
Ousseny Zerbo +5 more
semanticscholar +1 more source
npj Vaccines, 2019 Current acellular pertussis vaccines fall short of optimal protection against the human respiratory pathogen Bordetella pertussis resulting in increased incidence of a previously controlled vaccine- preventable disease.
Dylan T. Boehm +15 more
semanticscholar +1 more source
Frontiers in Immunology, 2018 Bordetella pertussis is the agent of pertussis, also referred to as whooping cough, a disease that remains an important public health issue. Vaccine-induced immunity to pertussis wanes over time. In industrialized countries, high vaccine coverage has not
S. Cauchi, C. Locht
semanticscholar +1 more source
Midwives\u27 knowledge, attitudes and learning needs regarding antenatal vaccination [PDF]
, 2018 Objective: To determine the knowledge, attitudes and learning needs of midwives regarding antenatal vaccination. Design & Setting: A cross-sectional, paper-based survey of midwives employed at the only public tertiary maternity hospital in the Australian
Amirthalingam +32 more
core +2 more sources
Journal of the Pediatric Infectious Diseases Society, 2018 Background Recent increases in pertussis morbidity and mortality rates among young infants have led to a recommendation in some countries for vaccination against pertussis during pregnancy.
B. Abu-Raya +32 more
semanticscholar +1 more source
Pertussis Toxin: A Key Component in Pertussis Vaccines?
Toxins, 2019 B. pertussis is a human-specific pathogen and the causative agent of whooping cough. The ongoing resurgence in pertussis incidence in high income countries is likely due to faster waning of immunity and increased asymptomatic colonization in individuals ...
Kelsey A. Gregg, Tod J. Merkel
doaj +1 more source
Journal of Infectious Diseases, 2017 Summary The resurgence of pertussis may originate from inefficient vaccine-mediated protection against infection by Bordetella pertussis. Here, we show that the live attenuated vaccine BPZE1 is safe in nonhuman primates and induces robust protection ...
C. Locht +7 more
semanticscholar +1 more source
Outer-Membrane-Vesicle-Associated O Antigen, a Crucial Component for Protecting Against Bordetella parapertussis Infection [PDF]
, 2018 Bordetella parapertussis is a respiratory-disease pathogen producing symptomatology similar to that of pertussis but of underestimated incidence and with no specific vaccine existing. We recently designed a vaccine candidate from B.
Bartel, Erika Belén +8 more
core +3 more sources
A Perturbative Approach to the Analysis of Many-Compartment Models Characterized by the Presence of Waning Immunity [PDF]
arXiv, 2021 The waning of immunity after recovery or vaccination is a major factor accounting for the severity and prolonged duration of an array of epidemics, ranging from COVID-19 to diphtheria and pertussis. To study the effectiveness of different immunity level-based vaccination schemes in mitigating the impact of waning immunity, we construct epidemiological ...
arxiv
Cold Spring Harbor Perspectives in Biology, 2017 Pertussis is resurgent in some countries, particularly those in which children receive acellular pertussis (aP) vaccines in early infancy and boosters later in life.
N. Burdin, Lori Handy, S. Plotkin
semanticscholar +1 more source