Results 41 to 50 of about 645,718 (276)

Bacterial outer membrane vesicles and vaccine applications [PDF]

, 2014
Vaccines based on outer membrane vesicles (OMV) were developed more than 20 years ago against Neisseria meningitidis serogroup B. These nano-sized structures exhibit remarkable potential for immunomodulation of immune responses and delivery of “self ...
Acevedo, Reinaldo, Acosta, Armando, Campa, Concepcion, Cardoso, Daniel, Fernandez, Sonsire, Ferro, Valerie, Garcia, Luis, Perez, Jose Luis, Rosenqvist, Einar, Sarmiento, Maria Elena, Zayas, Caridad   +10 more
core   +2 more sources

Evaluation of Whole-Cell and Acellular Pertussis Vaccines in the Context of Long-Term Herd Immunity

Vaccines, 2022
After the pertussis vaccine had been introduced in the 1940s and was shown to be very successful in reducing the morbidity and mortality associated with the disease, the possibility of improving both vaccine composition and vaccination schedules has ...
Ewa Szwejser-Zawislak, Mieszko M. Wilk, Piotr Piszczek, Justyna Krawczyk, Daria Wilczyńska, Daniela Hozbor   +5 more
doaj   +1 more source

A novel method for the extraction of outer membrane vesicles (OMVs) from Bordetella pertussis Tohama strain

Iranian Journal of Microbiology, 2020
Background and Objectives: There are many pertussis outbreaks which is mainly due to the reduction in the immunity of acellular pertussis (aP) vaccines. Therefore, there is a crucial necessity to develop a new generation of pertussis vaccine.
Mohammad Sekhavati, Ashraf Mohabati Mobarez, Seyed Davar Siadat, Mojtaba Noofeli   +3 more
doaj   +1 more source

What Is Wrong with Pertussis Vaccine Immunity? Why Immunological Memory to Pertussis Is Failing.

Cold Spring Harbor Perspectives in Biology, 2017
Memory responses seen after whole-cell pertussis (wP) and acellular pertussis (aP) vaccine priming are different and reflect better long-term protection against pertussis disease seen with the whole-cell vaccines.
D. Diavatopoulos, K. Edwards
semanticscholar   +1 more source

Membrane vesicles derived from Bordetella bronchiseptica: Active constituent of a new vaccine against infections caused by this pathogen [PDF]

, 2018
Bordetella bronchiseptica, a Gram-negative bacterium, causes chronic respiratory tract infections in a wide variety of mammalian hosts, including humans (albeit rarely).
Bartel, Erika Belén, Bottero, Daniela, Gaillard, María Emilia, Hozbor, Daniela Flavia, Vercellini, María Clara, Zurita, Maria Eugenia   +5 more
core   +2 more sources

Pregnancy has a minimal impact on the acute transcriptional signature to vaccination. [PDF]

, 2020
Vaccination in pregnancy is an effective tool to protect both the mother and infant; vaccines against influenza, pertussis and tetanus are currently recommended.
Aerssens, A, Calvert, A, Cizmeci, D, Hake, D, Jones, CE, Kaufmann, SHE, Leroux-Roels, G, Maertzdorf, J, Maes, C, Tregoning, JS, Weiner, J   +10 more
core   +1 more source

What Is Wrong with Pertussis Vaccine Immunity? Inducing and Recalling Vaccine-Specific Immunity.

Cold Spring Harbor Perspectives in Biology, 2017
The high incidence of pertussis in vaccinated adolescents suggests the failing of immune memory. We argue that acellular pertussis vaccines generate memory cells that are effectively reactivated by boosters better than by Bordetella pertussis exposure ...
C. Eberhardt, C. Siegrist
semanticscholar   +1 more source

Protection against pertussis in humans correlates to elevated serum antibodies and memory B cells [PDF]

, 2017
Pertussis is a respiratory infection caused by Bordetella pertussis that may be particularly severe and even lethal in the first months of life when infants are still too young to be vaccinated. Adults and adolescents experience mild symptoms and are the
Carsetti, Rita, Di Mattia, G., Fedele, Giorgio, Frassanito, A., Gesualdo, Francesco, Leone, Pasqualina, Marcellini, Valentina, Midulla, Fabio, Mortari, Eva Piano, Nenna, R., Pandolfi, Elisabetta, Stefanelli, Paola, The Pertussis Study, Gropu, Tozzi, Alberto Eugenio   +13 more
core   +1 more source

Association between pertussis vaccination coverage and other sociodemographic factors and pertussis incidence using surveillance data

Epidemics, 2023
Routine vaccination with pertussis vaccines has been successful in driving down pertussis mortality and morbidity globally. Despite high vaccination coverage, countries such as Australia, USA, and UK have experienced increase in pertussis activity over ...
Madhura S. Rane, Jonathan Wakefield, Pejman Rohani, M. Elizabeth Halloran   +3 more
doaj  

Association Between Vaccine Refusal and Vaccine-Preventable Diseases in the United States: A Review of Measles and Pertussis.

Journal of the American Medical Association (JAMA), 2016
IMPORTANCE Parents hesitant to vaccinate their children may delay routine immunizations or seek exemptions from state vaccine mandates. Recent outbreaks of vaccine-preventable diseases in the United States have drawn attention to this phenomenon ...
Varun K. Phadke, R. Bednarczyk, D. Salmon, S. Omer   +3 more
semanticscholar   +1 more source