Results 71 to 80 of about 1,328 (134)

Two types of coumarins-specific enzymes complete the last missing steps in pyran- and furanocoumarins biosynthesis

Acta Pharmaceutica Sinica B
Pyran- and furanocoumarins are key representatives of tetrahydropyrans and tetrahydrofurans, respectively, exhibiting diverse physiological and medical bioactivities. However, the biosynthetic mechanisms for their core structures remain poorly understood.
Yucheng Zhao, Yuedong He, Liangliang Han, Libo Zhang, Yuanzheng Xia, Fucheng Yin, Xiaobing Wang, Deqing Zhao, Sheng Xu, Fei Qiao, Yibei Xiao, Lingyi Kong   +11 more
doaj   +1 more source

Structure-based tailoring of the first coumarins-specific bergaptol O-methyltransferase to synthesize bergapten for depigmentation disorder treatment

Journal of Advanced Research, 2020
Bergapten has long been used in combination with ultraviolet A irradiation to treat depigmentation disorder. However, extremely low bergapten contents in plants and difficulties in synthesizing bergapten have limited its application.
Yucheng Zhao, Nana Wang, Huali Wu, Yuanze Zhou, Chuanlong Huang, Jun Luo, Zhixiong Zeng, Lingyi Kong   +7 more
doaj   +1 more source

genome and gene of Peucedanum praeruptorum

Peucedanum praeruptorum Dunn. (Apiaceae) has been used in traditional Chinese medicine for a long time. A telomere-to-telomere genome was assembled by the combination of PacBio HiFi, ONT ultra-long, and Hi-C data.
mingzhou bai (17989753)
core   +1 more source

Full-length transcriptome and RNA-Seq analyses offer new insights into the mechanisms underlying early bolting in Peucedanum praeruptorum Dunn (Apiaceae)

Industrial Crops and Products
Peucedanum praeruptorum Dunn, known as “Qianhu”, is a perennial herb with high value in traditional Chinese medicine. However, early bolting during cultivation significantly reduces both quality and yield, posing major challenges for its agricultural and
Mengli Zhou, Qi Wang, Siyu Chen, Weiyi Tang, Zongsuo Liang, Ruihong Wang   +5 more
doaj   +1 more source

A new xanthyletin-type coumarin from the roots of Peucedanum praeruptorum

, 2019
A new xanthyletin-type coumarin, neopeucedalactone (1), was isolated from the roots of Peucedanum praeruptorum Dunn. Its chemical structure was elucidated based on extensive spectroscopic interpretation.
Hui-Ming Hua (534567), Chi Gong (6188819), Xin-Yu Li (1378743), Yuan-Yuan Zu (6188816), Ming-Xu Tang (4570441), Wei Ning (430798), Sheng-Li Niu (1559965)   +6 more
core   +1 more source

Four PpMYB genes govern alternative transcription of the coumarin biosynthesis branch in a synergistic manner

Industrial Crops and Products
R2R3-type MYB transcription factors (TFs) play a crucial role in regulating plant secondary metabolism. However, the transcriptional regulatory mechanisms underlying coumarin biosynthesis in the medicinal industrial crop Peucedanum praeruptorum Dunn ...
Jinzhuo Yao, Ranran Liao, Yuxian Liu, Bangxing Han, Cheng Song   +4 more
doaj   +1 more source

Peucedanum ferulaceum (BOL0225319)

, 2023
Kingdom: PlantaeDivision: MagnoliophytaClass: EudicotsOrder: ApialesFamily: ApiaceaeScientific name: Peucedanum ferulaceum (Thunb.) Eckl.
Bolus Herbarium (9862976)
core   +1 more source

Peucedanum strictum (BOL0225313)

, 2023
Kingdom: PlantaeDivision: MagnoliophytaClass: EudicotsOrder: ApialesFamily: ApiaceaeScientific name: Peucedanum strictum (Spreng.) B.L.BurttSpecimen barcode ...
Bolus Herbarium (9862976)
core   +1 more source

Anti-osteoclastogenic activity of praeruptorin A via inhibition of p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca2+ oscillation.

PLoS ONE, 2014
BackgroundA decrease of bone mass is a major risk factor for fracture. Several natural products have traditionally been used as herbal medicines to prevent and/or treat bone disorders including osteoporosis.
Jeong-Tae Yeon, Kwang-Jin Kim, Sik-Won Choi, Seong-Hee Moon, Young Sik Park, Byung Jun Ryu, Jaemin Oh, Min Seuk Kim, Munkhsoyol Erkhembaatar, Young-Jin Son, Seong Hwan Kim   +10 more
doaj   +1 more source

Peucedanum tenuifolium (BOL0225312)

, 2023
Kingdom: PlantaeDivision: MagnoliophytaClass: EudicotsOrder: ApialesFamily: ApiaceaeScientific name: Peucedanum tenuifolium Thunb.Specimen barcode ...
Bolus Herbarium (9862976)
core   +1 more source