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Comparative Transcriptomics Unveil the Crucial Genes Involved in Coumarin Biosynthesis in Peucedanum praeruptorum Dunn [PDF]

Frontiers in Plant Science, 2022
Peucedanum praeruptorum Dunn is a commonly used traditional Chinese medicine that is abundant in furano- and dihydropyrano coumarins. When P. praeruptorum reaches the bolting stage, the roots gradually lignified, and the content of coumarins declines ...
Cheng Song, Muhammad Aamir Manzoor
exaly   +4 more sources

De novo transcriptome analysis of Cnidium monnieri (L.) Cuss and detection of genes related to coumarin biosynthesis [PDF]

PeerJ, 2020
Cnidium monnieri (L.) Cuss (C. monnieri) is one of the most widely used traditional herbal medicines, exhibiting a wide range of pharmacological functions for treating asynodia, trichomonas vaginitis, and osphyalgia.
Yuanyuan Shi, Shengxiang Zhang, Daiyin Peng, Chunmiao Shan, Liqiang Zhao, Bin Wang, Jiawen Wu   +6 more
doaj   +3 more sources

Integrated Metabolomic and Transcriptomic Analyses Reveal the Coumarin Biosynthesis Pathway and Key Regulatory Genes in the Pericarp of Zanthoxylum [PDF]

Plants
Coumarins in the pericarp of Zanthoxylum contribute to the characteristic numbing–aromatic flavor and are associated with diverse bioactivities. To characterize coumarin divergence between two Zanthoxylum materials, mature pericarps of Dahongpao Z ...
Shengqun Chen, Lianwen Shen, Yajun Zeng, Shijing Feng, Hong Luo, Gang Wang   +5 more
doaj   +2 more sources

Functional genomic investigation of CYP71AJ49 in Peucedanum praeruptorum Dunn: Agrobacterium-mediated overexpression reveals dual roles in drought adaptation and coumarin biosynthesis [PDF]

Frontiers in Plant Science
IntroductionDrought stress is one of the major limiting factors for plant growth and agricultural production worldwide. This study seeks to investigate the role and mechanism of CYP71AJ49, a key enzyme gene in the coumarin biosynthesis pathway, under ...
Maosuo Wang, Shenghua Wang, Huifang Chu, Qian Ruan, Jun Dai, Jun Dai, Peipei Wei, Peipei Wei   +7 more
doaj   +2 more sources

Recent advances in the biosynthesis of coumarin and its derivatives

Green Chemical Engineering
Coumarin and its derivatives, presenting in many organisms (plants, fungi, and bacteria), are critical metabolites composed of fused benzene and α-pyrone rings.
Yajun Yan, Yusong Zou, Yuxi Teng
exaly   +3 more sources

MYB transcription factors in Peucedanum Praeruptorum Dunn: the diverse roles of the R2R3-MYB subfamily in mediating coumarin biosynthesis [PDF]

BMC Plant Biology
Background The MYB superfamily (v-myb avian myeloblastosis viral oncogene homolog) plays a role in plant growth and development, environmental stress defense, and synthesis of secondary metabolites.
Ranran Liao, Jinzhuo Yao, Yingyu Zhang, Yuxian Liu, Haoyu Pan, Bangxing Han, Cheng Song   +6 more
doaj   +2 more sources

Quality formation in Peucedanum praeruptorum dunn: metabolite biosynthesis, geoherbal variation, and early bolting regulation [PDF]

Frontiers in Plant Science
Peucedanum praeruptorum Dunn is a traditional medicinal crop in which coumarins are the principal determinants of pharmacological efficacy and commercial quality.
Rubing Chen, Rubing Chen, Wei Wang, Cuiting Chen, Cuiting Chen, Zhengyang Xu, Jinbao Pu, Jinbao Pu, Pan Xu, Pan Xu   +9 more
doaj   +2 more sources

Integrated Transcriptomic and Metabolomic Analyses Identify Candidate Transcription Factors Associated with Flavonoid and Coumarin Accumulation in Psoralea corylifolia [PDF]

Biology
Background: Psoralea corylifolia is a widely used traditional medicinal plant, with its dried mature fruits as the main medicinal part. Flavonoids and coumarins are the primary bioactive compounds of this species.
Zhangyiyi You, Hanhong Liang, Huiting Liao, E Ou, Hongqiu Zhou, Xuanxuan Cheng, Hanjing Yan, Hongyang Gao, Zhong Li   +8 more
doaj   +2 more sources

Growth Year and Chemotype Synergistically Regulate Coumarin Accumulation and the Associated Transcriptional Profiles in Peucedanum praeruptorum Dunn [PDF]

Plants
Peucedanum praeruptorum is increasingly cultivated as wild resources are depleted. However, cultivated plants often contain lower levels of coumarins than wild individuals and may not meet the standards of the Chinese Pharmacopoeia.
Jiemei Jiang, Yang Liu, Jianan Yang, Longfeng Feng, Dong Wen, Min Li, Zhiming Zhu, Qiuling Wang, Zhihui Gao, Jianhe Wei   +9 more
doaj   +2 more sources

Isofraxidin biosynthesis in Chloranthus: genomic insights into metabolic evolution of an early angiosperm phytoalexin [PDF]

Frontiers in Plant Science
As an early-diverging angiosperm lineage, Chloranthaceae produces specialized coumarins with documented antimicrobial and anti-inflammatory activities, which contribute to its ecological success.
Yingying Liu, Yingying Liu, Lu Chen, Ping Li, Shugen Wei, Shugen Wei, Yuan Huang, Yuan Huang, Mengjin Tan, Mengjin Tan, Ying Wei, Ying Wei, Feng Peng, Feng Peng, Yu Pan, Lisha Song, Lisha Song, Lingyun Wan, Lingyun Wan, Zhigang Yan, Zhigang Yan, Lingjian Gui, Lingjian Gui   +22 more
doaj   +2 more sources