Results 21 to 30 of about 119,192 (151)

The Molecular and Structural Basis of O-methylation Reaction in Coumarin Biosynthesis in Peucedanum praeruptorum Dunn. [PDF]

Int J Mol Sci, 2019
Methoxylated coumarins represent a large proportion of officinal value coumarins while only one enzyme specific to bergaptol O-methylation (BMT) has been identified to date. The multiple types of methoxylated coumarins indicate that at least one unknown enzyme participates in the O-methylation of other hydroxylated coumarins and remains to be ...
Zhao Y, Wang N, Sui Z, Huang C, Zeng Z, Kong L.   +5 more
europepmc   +6 more sources

The telomere-to-telomere (T2T) genome of Peucedanum praeruptorum Dunn provides insights into the genome evolution and coumarin biosynthesis

GigaScience
Abstract Background Traditional Chinese medicine has used Peucedanum praeruptorum Dunn (Apiaceae) for a long time. Various coumarins, including the significant constituents praeruptorin (A–E), are the active constituents in the dried roots of P. praeruptorum.
Bai, Mingzhou, Jiang, Sanjie, Chu, Shanshan, Yu, Yangyang, Shan, Dai, Liu, Chun, Zong, Liang, Liu, Qun, Liu, Nana, Xu, Weisong, Mei, Zhanlong, Jian, Jianbo, Zhang, Chi, Zhao, Shancen, Chiu, Tsan-Yu, Simonsen, Henrik Toft   +15 more
semanticscholar   +6 more sources

Identification of Anti-Inflammatory Compounds from Peucedanum praeruptorum Roots by Using Nitric Oxide-Producing Rat Hepatocytes Stimulated by Interleukin 1β [PDF]

Molecules, 2023
The roots of Peucedanum praeruptorum Dunn and Angelica decursiva Franchet et Savatier are designated Zenko, which is a crude drug defined by the Japanese Pharmacopoeia.
Hiromu Ozaki, Yuto Nishidono, Airi Fujii, Tetsuya Okuyama, Kaito Nakamura, Takanori Maesako, Saki Shirako, Richi Nakatake, Ken Tanaka, Yukinobu Ikeya, Mikio Nishizawa   +10 more
doaj   +3 more sources

Genome sequencing-based transcriptomic analysis reveals novel genes in Peucedanum praeruptorum [PDF]

BMC Genomic Data, 2023
Background Peucedanum praeruptorum Dunn, a traditional Chinese herbal medicine, contains coumarin and volatile oil components that have clinical application value. However, early bolting often occurs in the medicinal materials of Apiaceae plants.
Cheng Song, Yingyu Zhang, Yunpeng Zhang, Shanyong Yi, Haoyu Pan, Ranran Liao, Yuanyuan Wang, Bangxing Han   +7 more
doaj   +3 more sources

Tissue-Specific Metabolite Profiling on the Different Parts of Bolting and Unbolting Peucedanum praeruptorum Dunn (Qianhu) by Laser Microdissection Combined with UPLC-Q/TOF–MS and HPLC–DAD [PDF]

Molecules, 2019
Background: Qianhu is a traditional Chinese medicine. It is thought that Qianhu roots will harden after bolting and not be suitable for medicinal purposes.
Ling Li Chen, Shan Shan Chu, Ling Zhang, Jin Xie, Min Dai, Xin Wu, Hua Sheng Peng   +6 more
doaj   +3 more sources

Protective effect of Peucedanum praeruptorum Dunn extract on oxidative damage of LLC‑PK1 cells induced by H₂O₂. [PDF]

Exp Ther Med, 2023
Peucedanum praeruptorum Dunn extract (PPDE) is a well-known treatment used in traditional Chinese medicines, where it is most commonly used to treat coughs and symptoms such as headaches and fever. In the present study, the antioxidant capacity of PPDE in vitro was determined by scavenging experiments using DPPH, ABTS+·, ·OH, and ·O2-.
Hu S, Wang P, Ke J, Hui J, Wang C, Luo J, Chen S.   +6 more
europepmc   +4 more sources

Peucedanum praeruptorum Dunn

, 2019
2.1. Identification of the cDNA encoding PAL in P. praeruptorum Using PAL sequences reported previously and our transcriptome database of P. praeruptorum (accession no. SRX997427) (Zhao et al., 2015), a BLAST search was conducted. According to the E -value of alignments, only one PAL was identified and cloned.
Sui, Ziwei, Luo, Jun, Yao, Ruolan, Huang, Chuanlong, Zhao, Yucheng, Kong, Lingyi   +5 more
openaire   +3 more sources

The complete plastome of Peucedanum praeruptorum (Apiaceae)

Mitochondrial DNA. Part B. Resources, 2019
Peucedanum praeruptorum is an important traditional herbal medicine unique to China. The complete chloroplast genome of P. praeruptorum was generated here using high-throughput sequencing. The plastome was 147,197 bp in size, which consisted of a pair of
Yingshuo Li, Maolin Geng, Zenglai Xu, Qiong Wang, Lingli Li, Ming Xu, Mimi Li   +6 more
doaj   +2 more sources

Effect of functional food raw material Peucedanum praeruptorum Dunn: a research update

Food Science and Technology, 2022
Abstract Peucedanum praeruptorum Dunn is a natural plant with expectorant, antitussive, anti-asthmatic, anti-inflammatory, antispasmodic and sedative effects. It is used in traditional Chinese medicine. The key active substances extracted after separation are also used to process functional food.
Yongjian DENG, Pan WANG, Chunlang RAN, Shiwen HU, Shaocheng CHEN   +4 more
openaire   +4 more sources

Qianhu (Peucedanum praeruptorum Dunn) Improves exercise capacity in mice by regulating Nrf2/HO-1 oxidative stress signaling pathway

Applied Biological Chemistry, 2023
This study assessed the effect of Qianhu (Peucedanum praeruptorum Dunn) on the recovery of movement in mice with D-galactose-induced dyskinesia. The evaluation of the ability of mice to exercise revealed that Qianhu increased the running and swimming ...
Bo Li, Yeni Wang, Xiaoguang Yang
doaj   +2 more sources