Results 31 to 40 of about 119,192 (151)

Peucedanum praeruptorum Dunn polysaccharides regulate macrophage inflammatory response through TLR2/TLR4-mediated MAPK and NF-κB pathways

Biomedicine & Pharmacotherapy, 2022
The present study was to investigate the molecular mechanisms underlying macrophage inflammatory response to polysaccharides from Peucedanum praeruptorum Dunn (PPDs) and elucidate the receptors and signaling pathways associated with PPDs-mediated macrophage activation.
Ming, Zhao, Jing, Hou, Sichun, Zheng, Xiaodan, Ma, Xinyu, Fu, Songhua, Hu, Kai, Zhao, Wei, Xu   +7 more
openaire   +3 more sources

Rapid Identification of Peucedanum praeruptorum Dunn and Its Adulterants by Hand-Held Near-Infrared Spectroscopy

Journal of AOAC INTERNATIONAL, 2021
Abstract Background Peucedanum praeruptorum Dunn (PPD) is a traditional Chinese medical herb of high medical and economic value. However, PPD is often adulterated by inexpensive plants. Objective In order to establish an integrated ...
Fang Wang, Bin Jia, Xiangwen Song, Jun Dai, Xiaoli Li, Haidi Gao, Haoyu Pan, Hui Yan, Bangxing Han   +8 more
openaire   +3 more sources

Elucidating the Furanocoumarin Biosynthetic Pathway in Apium graveolens L.: Uncovering the Coordination of Core Enzymes in Both Functional Activity and Gene Localization [PDF]

Plants
Furanocoumarins and their derivatives are found in various plant species and have attracted considerable attention due to their diverse biological activities. By analyzing the genomes of Apium Graveolens L.
Jiali Zhou, Bing Li, Bin Wang, Ronghua Zhang, Lian Duan   +4 more
doaj   +2 more sources

Full-length transcriptome and RNA-Seq analyses offer new insights into the mechanisms underlying early bolting in Peucedanum praeruptorum Dunn (Apiaceae)

Industrial Crops and Products
Peucedanum praeruptorum Dunn, known as “Qianhu”, is a perennial herb with high value in traditional Chinese medicine. However, early bolting during cultivation significantly reduces both quality and yield, posing major challenges for its agricultural and
Mengli Zhou, Qi Wang, Siyu Chen, Weiyi Tang, Zongsuo Liang, Ruihong Wang   +5 more
doaj   +2 more sources

The role of coumarin biosynthesis in modulating plant drought responses: insights from PpBMT overexpression in Arabidopsis [PDF]

BMC Plant Biology
Background PpBMT encodes the bergaptol O-methyltransferase from the medicinal plant Peucedanum praeruptorum Dunn and belongs to the O-methyltransferase gene family.
Peipei Wei, Qian Ruan, Qihui Yin, Huifang Chu, Yongchang Cao, Cheng Song, Yiwen Zhang, Jun Dai   +7 more
doaj   +2 more sources

Establishment of regeneration system of Peucedanum praeruptorum and molecular association analysis of coumarin secondary metabolism [PDF]

Frontiers in Plant Science
IntroductionPeucedanum praeruptorum is a medicinally critical species whose sustainable utilization is hindered by declining wild populations and insufficient cultivation systems.
Liu Tianliang, Liu Tianliang, Wang Liang, Zhang Yudan, Zheng Yujiao, Zhou Tao, Huang Luqi   +6 more
doaj   +2 more sources

Peucedanum praeruptorum Dunn

, 1992
Qianhu, Radix Peucedani, is the dry root of Peucedanum praeruptorum Dunn or P. decursivum Maxim. (Apiaceae) collected in the winter or spring. It is officially listed in the Chinese Pharmacopoeia and could be used as an expectorant and mucolytic.
Weici Tang, Gerhard Eisenbrand
openaire   +2 more sources

Integration of a decrescent transcriptome and metabolomics dataset of Peucedanum praeruptorum to investigate the CYP450 and MDR genes involved in coumarins biosynthesis and transport [PDF]

Frontiers in Plant Science, 2015
Peucedanum praeruptorum Dunn is well-known traditional Chinese medicine. However, little is known in the biosynthesis and the transport mechanisms of its coumarin compounds at the molecular level.
Yucheng eZhao, Tingting eLiu, Jun eLuo, Qian eZhang, Sheng eXu, Chao eHan, Jinfang eXu, Menghan eChen, Yijun eChen, Lingyi eKong   +9 more
doaj   +2 more sources

Isolation of praeruptorins A and B from Peucedanum praeruptorum Dunn. and their general pharmacological evaluation in comparison with extracts of the drug

Il Farmaco, 2001
The root of Peucedanum praeruptorum Dunn. was extracted with solvents at different polarity obtaining three chemical fractions: aqueous (H2O), n-butanol (BuOH) and ethyl acetate (AcOEt). From AcOEt praeruptorins A and B were isolated by column chromatography on silica gel, using toluene/ethyl acetate as eluent, and identified by 1H and 13C NMR analysis.
Mei Lu, NICOLETTI, Marcello, Lucia Battinelli, MAZZANTI, Gabriela   +3 more
openaire   +4 more sources

Functional characterization and correlation analysis of phenylalanine ammonia-lyase (PAL) in coumarin biosynthesis from Peucedanum praeruptorum Dunn

Phytochemistry, 2019
Coumarins exhibit many biological activities and are the main specialised metabolites of Peucedanum praeruptorum Dunn, an important plant used in traditional Chinese medicine. In preliminary studies, we cloned several genes involved in coumarin biosynthesis in P. praeruptorum, such as 4-coumarate: CoA ligase (4CL), p-coumaroyl CoA 2'-hydroxylase (C2'H),
Sui, Ziwei, Luo, Jun, Yao, Ruolan, Huang, Chuanlong, Zhao, Yucheng, Kong, Lingyi   +5 more
openaire   +3 more sources