Results 121 to 130 of about 4,214 (236)

Autophagy in Trypanosomatids

Cells, 2012
Autophagy is a ubiquitous eukaryotic process that also occurs in trypanosomatid parasites, protist organisms belonging to the supergroup Excavata, distinct from the supergroup Opistokontha that includes mammals and fungi.
Paul A. M. Michels, Eva Rico, Ana Brennand   +2 more
doaj   +1 more source

Apm4, the mu subunit of yeast AP-2 interacts with Pkc1, and mutation of the Pkc1 consensus phosphorylation site Thr176 inhibits AP-2 recruitment to endocytic sites. [PDF]

The AP-2 endocytic adaptor has been extensively characterized in mammalian cells and is considered to play a role both in cargo binding and in formation of endocytic sites.
Andrews PD, Bernardo Chapa-y-Lazo, Kathryn R Ayscough, Nonaka H   +3 more
core   +1 more source

Abnormal cell-clearance and accumulation of autophagic vesicles in lymphocytes from patients affected with Ataxia-Teleangiectasia [PDF]

, 2017
Ataxia-Teleangiectasia (A-T) is a neurodegenerative disorder due to mutations in ATM gene. ATM in the nucleus ensures DNA repair, while its role in the cytosol is still poorly clarified.
BALLABIO, ANDREA, Bianchino, Gabriella, D'ASSANTE, ROBERTA, FUSCO, ANNA, Grieco, Vitina, PALAMARO, LOREDANA, PIGNATA, CLAUDIO, Polishchuk, Elena, Polishchuk, Roman, PRENCIPE, MARIA ROSARIA   +9 more
core   +1 more source

The mammalian ULK1 complex and autophagy initiation [PDF]

, 2017
Autophagy is a vital lysosomal degradation pathway that serves as a quality control mechanism. It rids the cell of damaged, toxic or excess cellular components, which if left to persist could be detrimental to the cell.
Bach, Bento, Chan, Chan, Chauhan, Chen, Cheong, Chude, Di Bartolomeo, Dunlop, Egan, Egan, Farre, Fullgrabe, Gammoh, Gan, Gan, Ganley, Henckaerts, Hieke, Hosokawa, Hosokawa, Ian G. Ganley, Itakura, James T. Murray, Jiang, Jon D. Lane, Joo, Jung, Kaizuka, Kaizuka, Karanasios, Karanasios, Kim, Konno, Koyama-Honda, Kundu, Lamark, Lazarou, Lazarus, Lee, Li, Li, Li, Li, Lim, Lin, Lin, Liu, Liu, Maria Zachari, McWilliams, Mercer, Nazio, Nazio, Ochaba, Orsi, Pengo, Petherick, Pickrell, Pike, Puente, Puri, Qi, Rabanal-Ruiz, Rui, Russell, Sarraf, Schneider, Sellier, Su, Sun, Suzuki, Tian, Torii, Ugolino, Viktor I. Korolchuk, Wang, Webster, Wold, Wong, Wu, Xu, Yang, Young, Yun, Zhou, Zou   +87 more
core   +2 more sources

pexophagy

Citation: 'pexophagy' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13558 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Using the hierarchy of biological ontologies to identify mechanisms in flat networks [PDF]

, 2017
Systems biology has provided new resources for discovering and reasoning about mechanisms. In addition to generating databases of large bodies of data, systems biologists have introduced platforms such as Cytoscape to represent protein–protein ...
Bechtel, William
core   +1 more source

Pex3 and Atg37 compete to regulate the interaction between the pexophagy receptor, Atg30, and the Hrr25 kinase [PDF]

, 2017
Katarzyna Zientara‐Rytter, Katharine Ozeki, Taras Y. Nazarko, Suresh Subramani   +3 more
openalex   +1 more source

Hypoxia signaling pathways: modulators of oxygen-related organelles

Frontiers in Cell and Developmental Biology, 2015
Oxygen (O2) is an essential substrate in cellular metabolism, bioenergetics, and signaling and as such linked to the survival and normal function of all metazoans.
Miriam Johanna Schönenberger, Miriam Johanna Schönenberger, Werner Josef Kovacs   +2 more
doaj   +1 more source

From homeostasis to pathology, organelle-specific autophagy in skeletal muscle: a PRISMA-ScR scoping review

Frontiers in Physiology
BackgroundAs the largest metabolic organ in the human body, skeletal muscle relies on the structural and functional integrity of its organelles for cellular viability and responsiveness.
Chunxiao Wang, Guanghua Liu, Changsheng Guo, Qi Li, Feixiao Wang, Ming Zhang   +5 more
doaj   +1 more source

NGS Screening for Identification of Novel Pexophagy-Related Mutation in Arabidopsis thaliana [PDF]

, 2020
Katarzyna Sieńko, Kacper Żukowski, Kenji Yamada, Shino Goto‐Yamada   +3 more
openalex   +1 more source