Results 101 to 110 of about 4,214 (236)

New Data On Isopenicillin N Synthase And Peroxisome Co-Location In The Hyphal Cells Of Penicillium Chrysogenum PQ-96 – Pexophagy And Exocytosis

open access: yesPostępy Mikrobiologii, 2019
The machinery of antibiotic production by Penicillium chrysogenum PQ-96 is composed of co-located cytosolic and peroxisomal enzymes of the penicillin G biosynthesis pathway.
Kurzątkowski Wiesław   +4 more
doaj   +1 more source

Autophagy Stimulus-Dependent Role of the Small GTPase Ras2 in Peroxisome Degradation

open access: yesBiomolecules, 2020
The changing accessibility of nutrient resources induces the reprogramming of cellular metabolism in order to adapt the cell to the altered growth conditions. The nutrient-depending signaling depends on the kinases mTOR (mechanistic target of rapamycin),
Fahd Boutouja, Harald W. Platta
doaj   +1 more source

A molecular genetic toolbox for Yarrowia lipolytica [PDF]

open access: yes, 2017
Background: Yarrowia lipolytica is an ascomycete yeast used in biotechnological research for its abilities to secrete high concentrations of proteins and accumulate lipids.
Baker, Scott E.   +5 more
core   +4 more sources

Organellar quality control crosstalk in aging‐related disease: Innovation to pave the way

open access: yesAging Cell, Volume 24, Issue 1, January 2025.
Organellar homeostasis and inter‐organelle crosstalk are vital for cell survival. Quality control systems (QCS) maintain this balance, and their dysfunction is linked to aging‐related diseases like neurodegeneration and cancer. Our review explores QCS interactions among organelles and discusses potential therapies, aiming to identify new therapeutic ...
Yu Li   +4 more
wiley   +1 more source

Starvation-response may not involve Atg1-dependent autophagy induction in non-unikont parasites [PDF]

open access: yes, 2014
Autophagy, the lysosome-mediated self-degradation process, is implicated in survival during starvation in yeast, Dictyostelium and animals. In these eukaryotic taxa (collectively called Unikonts), autophagy is induced primarily through the Atg1/ULK1 ...
Ari, Eszter   +4 more
core   +3 more sources

Molecular Symphony of Mitophagy: Ubiquitin‐Specific Protease‐30 as a Maestro for Precision Management of Neurodegenerative Diseases

open access: yesCNS Neuroscience &Therapeutics, Volume 31, Issue 1, January 2025.
Novel Ubiquitin‐Specific Protease‐30 (USP30) inhibitors target a key deubiquitinating enzyme, USP30, promoting the ubiquitination and subsequent clearance of dysfunctional mitochondria through the mitophagy pathway. This process offers therapeutic benefits in neurodegenerative diseases by enhancing neuronal cell health.
Ankit Siwach   +3 more
wiley   +1 more source

Selective Autophagy of Peroxisomes in Plants: From Housekeeping to Development and Stress Responses

open access: yesFrontiers in Plant Science, 2019
Peroxisomes are dynamic organelles involved in multiple functions, including oxygen and nitrogen reactive species metabolism. In plants, these organelles have a close relationship with chloroplasts and mitochondria, characterized by intense metabolic ...
Adela Olmedilla, Luisa M. Sandalio
doaj   +1 more source

PEX13 prevents pexophagy by regulating ubiquitinated PEX5 and peroxisomal ROS [PDF]

open access: green, 2022
Nicholas D. Demers   +10 more
openalex   +1 more source

ACBD5 and VAPB mediate membrane associations between peroxisomes and the ER [PDF]

open access: yes, 2016
This is the final version of the article. Available from the publisher via the DOI in this record.Peroxisomes (POs) and the endoplasmic reticulum (ER) cooperate in cellular lipid metabolism and form tight structural associations, which were first ...
Abu-Safieh   +62 more
core   +2 more sources

Molecular evolution and interaction of ROS with ion transport for plant abiotic stresses

open access: yesNew Plant Protection, Volume 1, Issue 2, December 2024.
Through a comprehensive review of the literature and analyses of the molecular evolution and comparative genetics of ROS‐regulated proteins and Shaker‐type K+ channels, we propose that ROS‐regulated proteins are essential players in response to and adaptation to abiotic stresses in green plants.
Hanxia Yu   +8 more
wiley   +1 more source

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