Results 131 to 140 of about 11,617 (181)

The brain-meningeal interface functions as a reservoir and entry site for brain parenchymal macrophages

open access: yes
Hutter G   +24 more
europepmc   +1 more source

Glycoprotein VI is a receptor for the PF4/anti-PF4 IgG complex and contributes to platelet activation in HIT

open access: yes
Francischetti, Ivo M.B.   +4 more
openaire   +1 more source

Platelet-activating anti-PF4 disorders: An overview

open access: yesSeminars in Hematology, 2022
Platelet factor 4 (PF4) is a highly cationic tetrameric protein that can be targeted by platelet-activating anti-PF4 antibodies of immunoglobulin G (IgG) class. Certain features of PF4, including its multivalent nature (duplicate antigen sites per tetramer), the ability of many PF4 tetramers to undergo close approximation through charge neutralization,
Theodore E. Warkentin
exaly   +3 more sources

The immunology of PF4 polyanion interactions

Current Opinion in Hematology, 2023
Purpose of review Platelet factor 4 (PF4, CXCL4), the most abundant α-granule platelet-specific chemokine, forms tetramers with an equatorial ring of high positive charge that bind to a wide range of polyanions, after which it changes conformation to expose antigenic epitopes.
Anh T P, Ngo   +2 more
openaire   +2 more sources

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