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Amodiaquine resistance is not related to rare findings of pfmdr1 gene amplifications in Kenya
Tropical Medicine & International Health, 2006SummaryObjectives Many countries are now adopting artemisinin‐based combination therapy (ACT) for treatment of Plasmodium falciparum malaria. In multi‐drug resistant areas in South East Asia amplifications of the pfmdr1 gene are frequent and tentatively associated with reduced susceptibility to the common quinoline partner drugs mefloquine and ...
Gabrielle, Holmgren +2 more
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Heterologous Expression and ATPase Activity of Mutant versus Wild Type PfMDR1 Protein
Biochemistry, 2007Mutation of the P. falciparum chloroquine resistance transporter (PfCRT) causes resistance to chloroquine (CQ) and other antimalarial drugs. Mutation and/or overexpression of one of the multidrug resistance protein homologues found in this malarial parasite (PfMDR1) may further modify or tailor the degree of multidrug resistance.
Linda E, Amoah +2 more
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Molecular Analysis of Pfmdr1 Gene in Plasmodium falciparum in Thai-Cambodia Border
2017Journal of Health Research, 31, Suppl.2 ...
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Pfmdr1 gene and chloroquine resistance
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1998openaire +2 more sources
Pfmdr1 gene and chloroquine resistance: a reply
Transactions of the Royal Society of Tropical Medicine and Hygiene, 1998openaire +1 more source
[12] Functional analysis of pfmdr1 gene of Plasmodium falciparum
1998Sarah Volkman, Dyann Wirth
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