Results 1 to 10 of about 133,795 (342)

Circulating prostaglandin E2 concentrations decrease at birth in premature lambs [PDF]

Frontiers in Pediatrics
RationaleDuring pregnancy, prostaglandin E2 (PGE2) is released from the placenta and circulates in relatively high concentrations in the fetus. As PGE2 suppresses breathing, PGE2 concentrations must decrease after birth, but the timing and mechanisms ...
Timothy J. R. Panneflek, Janneke Dekker, Kelly J. Crossley, Kelly J. Crossley, Cailin Diedericks, Cailin Diedericks, Kristel L. A. M. Kuypers, Ebony R. Cannata, Ebony R. Cannata, Paige J. Riddington, Paige J. Riddington, Femmie E. Bloem, Alison M. Thiel, Alison M. Thiel, Thomas van den Akker, Thomas van den Akker, Graeme R. Polglase, Graeme R. Polglase, Arjan B. te Pas, Stuart B. Hooper, Stuart B. Hooper, Indya M. Davies, Indya M. Davies   +22 more
doaj   +2 more sources

The Effect of Evening Primrose (Oenothera biennis) on the Some Biochemical Parameters in Rats with Gentamicin Induced Nephrotoxicity

Turkish Journal of Agriculture: Food Science and Technology, 2021
In this study, it was aimed to investigate the effect of evening primrose oil (EPO) on some biochemical parameters on nephrotoxicity induced by gentamicin (GM) in rats.
Murat Medineli, Handan Mert, Kıvanç İrak, Nihat Mert   +3 more
doaj   +1 more source

Immune Response in Pregnant Women Infected with Acute Vaginal Abscess Caused by Staphylococcus aureus and Trichomonas vaginalis [PDF]

Journal of Clinical and Diagnostic Research, 2018
Introduction: Vaginal abscess in pregnant women caused by Staphylococcus aureus and Trichomonas vaginalis is one of the most important disease. This infection is still medically uncontrolled because of poor health awareness due to the absence of personal
Ahmed Abduljabbar Jaloob Aljanaby, Saleem Alhadraawy, Sukayna Mushattat   +2 more
doaj   +1 more source

Tyk2-mediated homeostatic control by regulating the PGE2-PKA-IL-10 axis

AIMS Allergy and Immunology, 2021
Tyrosine kinase 2 (Tyk2), which associates with the receptors for type I interferon (IFN) and interleukins (IL)-6, IL-10, IL-12, and IL-23, is critical to mediate cytokine-induced signals.
Ryuta Muromoto, Kenji Oritani, Tadashi Matsuda   +2 more
doaj   +1 more source

Stromal-like Wilms tumor cells induce human Natural Killer cell degranulation and display immunomodulatory properties towards NK cells

OncoImmunology, 2021
The similarity of stromal-like Wilms tumor (str-WT) cells with mesenchymal stem cells (MSC), suggests their relevant role in the interplay with immune cells in the tumor microenvironment. We investigated the interaction between str-WT cells and NK cells.
Claudia Cantoni, Martina Serra, Erica Parisi, Bruno Azzarone, Angela Rita Sementa, Luigi Aurelio Nasto, Lorenzo Moretta, Giovanni Candiano, Cristina Bottino, Gian Marco Ghiggeri, Grazia Maria Spaggiari   +10 more
doaj   +1 more source

Wnt signaling enhances macrophage responses to IL-4 and promotes resolution of atherosclerosis

eLife, 2021
Atherosclerosis is a disease of chronic inflammation. We investigated the roles of the cytokines IL-4 and IL-13, the classical activators of STAT6, in the resolution of atherosclerosis inflammation.
Ada Weinstock, Karishma Rahman, Or Yaacov, Hitoo Nishi, Prashanthi Menon, Cyrus A Nikain, Michela L Garabedian, Stephanie Pena, Naveed Akbar, Brian E Sansbury, Sean P Heffron, Jianhua Liu, Gregory Marecki, Dawn Fernandez, Emily J Brown, Kelly V Ruggles, Stephen A Ramsey, Chiara Giannarelli, Matthew Spite, Robin P Choudhury, P'ng Loke, Edward A Fisher   +21 more
doaj   +1 more source

The association between repeated doses of vaginal PGE2 (Dinoprostone, Prostin®) and both maternal and neonatal outcomes among women in the north of Jordan

Clinical and Experimental Obstetrics & Gynecology, 2020
Objective: To evaluate the association between repeated doses of vaginal PGE2 and the maternal and neonatal outcomes for primigravid and multiparous women. Study design: A retrospective descriptive study was conducted at a teaching university hospital in
A.M. Sindiani, H.M. Rawashdeh, E.H. Alshdaifat, O.F. Altal, H. Yaseen, A.A. Alhowary   +5 more
doaj   +1 more source

Prostaglandin E2 promotes features of replicative senescence in chronically activated human CD8+ T cells. [PDF]

, 2014
Prostaglandin E2 (PGE2), a pleiotropic immunomodulatory molecule, and its free radical catalyzed isoform, iso-PGE2, are frequently elevated in the context of cancer and chronic infection.
Chou, Jennifer P, Effros, Rita B, Koduri, Megha P, Ramirez, Christina M, Ryba, Danielle M   +4 more
core   +2 more sources

Kaempferol Improves Breast Cancer-Related Depression through the COX-2/PGE2 Pathway

Frontiers in Bioscience-Landmark, 2023
Background: Breast cancer-related depression (BCRD) is strongly associated with BC and increases recurrence and mortality. This study investigated the role of kaempferol in the pathogenesis of BCRD and its underlying mechanism.
Qing Zhu, Yuanshan Han, Ying He, Yilan Fu, Hui Yang, Yun Chen, Yingrui Shi   +6 more
doaj   +1 more source

Ciprofloxacin reduces the stimulation of prostaglandin E2 output by interleukin-1 in human tendon-derived cells [PDF]

, 2003
Fluoroquinolone antibiotics such as ciprofloxacin can induce tendon pathology and have various effects on tendon-derived cells in culture. We are investigating whether ciprofloxacin modifies signalling responses in tendon cells.
Corps, AN, Curry, VA, Dutt, D, Harrall, RL, Hazleman, BL, Riley, GP   +5 more
core   +1 more source