Obesity, white adipose tissue and cancer
White adipose tissue (WAT) is essential for energy balance and hormone regulation. In obesity, WAT becomes dysfunctional, leading to inflammation and other changes that promote different stages of carcinogenesis. This review explores how unhealthy WAT under obese conditions supports carcinoma growth through both systemic effects and modulation of the ...
Estel SolsonaâVilarrasa+1 more
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Spatial mapping of the AA-PGE<sub>2</sub>-EP axis in multiple sclerosis lesions. [PDF]
Hansen CE+15 more
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A study of PGE2-induced phosphatidylinositol breakdown in aminonucleoside nephrotic rat kidney.
Junzo Suzuki+5 more
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Effects of leptin administration and feed restriction on thecal leucocytes in the preovulatory rat ovary and the effects of leptin on meiotic maturation, granulosa cell proliferation, steroid hormone and PGE2 release in cultured rat ovarian follicles [PDF]
P. Duggal
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Zic family member 5 promotes RIO kinase 3 expression to enhance pancreatic cancer survival
This study demonstrates that targeting ZIC5 increases gemcitabine sensitivity and induces pancreatic cancer shrinkage in vivo. The findings also show that ALDH3B1, PTGES, and TUFT1, the downstream genes of ZIC5, contribute to gemcitabine resistance in pancreatic cancer cells.
Reiko Satow+7 more
wiley +1 more source
MLKL is involved in the regulation of skin wound healing and interplay between macrophages and myofibroblasts in mice. [PDF]
Zhao J+8 more
europepmc +1 more source
Epidermal anti-Inflammatory properties of 5,11,14 20:3: effects on mouse ear edema, PGE2 levels in cultured keratinocytes, and PPAR activation. [PDF]
Alvin Berger+5 more
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Activation of notch signaling pathway is a potential mechanism for mucin2 reduction and intestinal mucosal barrier dysfunction in high-altitude hypoxia. [PDF]
Jia R+8 more
europepmc +1 more source
EFFECTS OF 2 h OF EXERCISE AND IN VIVO INDOMETHACIN ON CIRCULATING PGE2 LEVELS AND NK CELL ACTIVITY
Shawn G. Rhind+4 more
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