Results 191 to 200 of about 133,795 (342)

COX-2/PGE₂ axis blockade with celecoxib enhances anti-PD-1 efficacy by activating natural killer cells for residual hepatocellular carcinoma after radiofrequency ablation. [PDF]

J Exp Clin Cancer Res
Lei Y, Bai Y, Bai X, Sun B, Zhu L, Wu W, Su Y, Zhang H, Wang Y, Zheng C.   +9 more
europepmc   +1 more source

Therapeutic effect of NEO400, perillyl alcohol conjugated to linoleic acid, in a mouse model of UV‐induced skin damage

Photochemistry and Photobiology, Volume 101, Issue 2, Page 338-349, March/April 2025.
In the present work with mouse models, we demonstrate that a novel compound, NEO400, is able to profoundly protect skin against damage caused by UV radiation (UVR) when it is applied to skin post‐UVR exposure. In comparison, Aloe vera or linoleic acid are unable to achieve a similar level of protection.
Stephen Swenson, Catalina Silva‐Hirschberg, Liliana Freeland, Kristen L. Chen, Nagore I. Marín‐Ramos, Axel H. Schönthal, Thomas C. Chen   +6 more
wiley   +1 more source

[Temporal changes of chronic postsurgical pain in mice: the regulatory role of CX3CL1 in the dorsal root ganglion]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Zhao B, Lü Z, Ji D, Tian S, Wu Y, Li X, Zhou J, Fang J, Liang Y.   +8 more
europepmc   +1 more source

Thymoquinone Upregulates microRNA-199a-3p and Downregulates COX-2 Expression and PGE2 Production via Deactivation of p38/ERK/JNK-MAPKs and p65/p50-NF-κB Signaling in Human Lung Cancer Cells [PDF]

Yusuf S. Khan, Aisha Farhana, Ghorashy Eltayeb Yousif Mohammed, Abuzar Abdulwahab Osman, Abdullah Alsrhani, Syed Monowar Alam Shahid, Mohammed Kuddus, Zafar Rasheed   +7 more
openalex   +1 more source

Alleviation of photoaging‐associated MMP upregulation, prostanoid biosynthesis, and cell cycle arrest with titanium dioxide, zinc oxide, and inorganic‐only (ZnO + TiO2) sunscreens

Photochemistry and Photobiology, EarlyView.
Inorganic sunscreens containing the UV filters titanium dioxide (TiO2) and/or zinc oxide (ZnO) alleviated various biomarkers of photoaging in human dermal fibroblasts, at a gene and protein level. The study provides novel insights that observe the impact of inorganic photoprotection through the molecular biology of skin.
Neil Dominic T. Pangilinan, Mohammad Shalbaf, Aline Souza, Bhaven Chavan, Mark A. Birch‐Machin   +4 more
wiley   +1 more source

The Role of Prostaglandins as Major Inflammatory Mediators in Colorectal Cancer. [PDF]

Int J Mol Sci
Macia Guardado M, Lutz V, Hengstschläger M, Dolznig H.   +3 more
europepmc   +1 more source

Supplemental Figure 3 from Blockade of the PGE2 Pathway Inhibits the Growth of PTEN-Deficient HNSCC Tumors

Jacqueline P. Nguyen, Shorook Na’ara, Liam C. Woerner, Nathan K. VanLandingham, Marius Hoerner, Rodell T. Santuray, Kelly Blum, Mi‐Ok Kim, Daniel E. Johnson, Jennifer R. Grandis   +9 more
openalex   +1 more source

Brain regulates weight bearing bone through PGE2 skeletal interoception: implication of ankle osteoarthritis and pain [PDF]

Feng Gao, Qimiao Hu, Wenwei Chen, Jilong Li, Cheng Qi, Yiwen Yan, Cheng Qian, Mei Wan, James R. Ficke, Junying Zheng, Xu Cao   +10 more
openalex   +1 more source

Inflammation and mechanical force‐induced bone remodeling

Periodontology 2000, EarlyView.
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon, Xin Huang, Leticia Rojas Cortez, Puttipong Sripinun, Jung‐me Lee, Julie J. Hong, Dana T. Graves   +6 more
wiley   +1 more source

Molecular basis of prostaglandin E₂ reuptake by organic anion transporter PGT. [PDF]

Nat Commun
Zhu Z, Li Y, Xia H, Yang C, Zhou Z, Chao Y, Ba Q, Li D, Qu Q.   +8 more
europepmc   +1 more source