Results 11 to 20 of about 60,514 (230)

Immunofluorescent localization of PGK-1 and PGK-2 isozymes within specific cells of the mouse testis [PDF]

Developmental Biology, 1981
Abstract The ubiquitous isozyme of phosphoglycerate kinase, PGK-1, and the testis-specific isozyme, PGK-2, have been localized to specific cells of the testis by indirect immunofluorescence on Bouin's fixed testis sections. The earliest cell of the spermatogenic series in which PGK-2 is detectable by immunofluorescence is the Stage 12 spermatid.
Kramer, James M.
openaire   +4 more sources

The Phosphoglycerate Kinase (PGK) Gene Family of Maize (Zea mays var. B73)

Plants, 2020
Phosphoglycerate kinase (PGK, E.C. 2.7.2.3) interconverts ADP + 1,3-bisphospho-glycerate (1,3-bPGA) to ATP + 3-phosphoglycerate (3PGA). While most bacteria have a single pgk gene and mammals possess two copies, plant genomes contain three or more PGK ...
Julio A. Massange-Sánchez, Luz E. Casados-Vázquez, Sheila Juarez-Colunga, Ruairidh J. H. Sawers, Axel Tiessen   +4 more
doaj   +2 more sources

Transcriptional Control of the Saccharomyces cerevisiae PGK Gene by RAP1 [PDF]

Molecular and Cellular Biology, 1989
The promoter of the yeast glycolytic gene encoding phosphoglycerate kinase (PGK) contains an upstream activation sequence between bases -538 and -402 upstream of the initiating ATG. The upstream activation sequence contains multiple functional elements, including an essential region called the activator core (AC) sequence and three copies of the ...
Chambers, A, Tsang, JSH, Stanway, C, Kinsgman, AJ, Kingsman, SM   +4 more
openaire   +4 more sources

Molecular evolution of the human Pgk-2 retroposon [PDF]

Nucleic Acids Research, 1990
The human phosphoglycerate kinase (Pgk) gene family includes the functional, intronless Pgk-2 gene and the intronless psi hPgk-1 pseudogene, both of which are retroposons of the intron-containing Pgk-1 gene. The divergence of the Pgk-2 retroposon from Pgk-1 is compared with that of the psi hPgk-1 retroposon from Pgk-1 to reveal nucleotide ...
John R. Mccarrey
openaire   +3 more sources

Early-onset parkinsonism in a pedigree with phosphoglycerate kinase deficiency and a heterozygous carrier: do PGK-1 mutations contribute to vulnerability to parkinsonism?

npj Parkinson's Disease, 2017
Early-onset Parkinson’s disease: a new genetic link Mutations in the gene encoding phosphoglycerate kinase 1 (PGK-1) may confer susceptibility to early-onset Parkinson’s disease (PD).
Satoshi Sakaue, Takashi Kasai, Ikuko Mizuta, Masaya Suematsu, Shinya Osone, Yumiko Azuma, Toshihiko Imamura, Takahiko Tokuda, Hitoshi Kanno, Omar M. A. El-Agnaf, Masafumi Morimoto, Masanori Nakagawa, Hajime Hosoi, Toshiki Mizuno   +13 more
doaj   +2 more sources

The Denatured State of N-PGK Is Compact and Predominantly Disordered [PDF]

Journal of Molecular Biology, 2009
The organisation of the structure present in the chemically denatured N-terminal domain of phosphoglycerate kinase (N-PGK) has been determined by paramagnetic relaxation enhancements (PREs) to define the conformational landscape accessible to the domain.
Cliff, M.J., Craven, C.J., Marston, J.P., Hounslow, A.M., Clarke, A.R., Waltho, J.P.   +5 more
openaire   +4 more sources

Transcription factor interactions at the PGK promoter in yeast [PDF]

, 1996
Two new transcription factor binding sites have been identified within the phosphoglycerate kinase (PGK) gene promoter in the yeast Saccharomyces cerevisiae. The binding sites are upstream of the previously defined UAS, and are bound in vitro by the multifunctional transcription factors Reb1p and Cpf1p.
Packham, Elizabeth A.
openaire   +3 more sources

Extracellular Vesicle-Associated IL4 Displays Enhanced Anti-Inflammatory Properties in Microglial Cells. [PDF]

J Extracell Biol
ABSTRACT Neuroinflammation and neurodegeneration are strictly related phenomena, characterized by dysregulation of microglia, central nervous system (CNS) resident immune cells. Interleukin‐4 (IL4) has shown beneficial abilities to re‐establish microglial homeostasis in experimental models of CNS traumatic injury, stroke and multiple sclerosis, but its
Marostica G, Frigè C, Finardi A, Mandelli A, Manenti S, Siciliani S, Podini P, De Curtis I, Muzio L, Rossi E, de Candia P, Furlan R.   +11 more
europepmc   +2 more sources

HIV-1 establishes immediate latency in T cells expressing the viral Nef protein. [PDF]

FEBS Open Bio
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Lam C, Sadowski I.
europepmc   +2 more sources

Faktor Risiko Prenatal Terhadap Kejadian Penyakit Ginjal Kronik derajat III-V di RSUP Dr. Kariadi Semarang

Sari Pediatri, 2020
Latar belakang. Kelainan ginjal kongenital menyebabkan hampir 60% penyakit ginjal kronik (PGK) pada anak. Faktor kesehatan maternal serta kondisi intrauterin akan memengaruhi kesehatan bayi yang dilahirkan dan dapat memprediksi adanya kelainan ginjal ...
Khotimatun Hasanah, R. Rochmanadji Widajat, Omega Mellyana   +2 more
doaj   +1 more source