Results 131 to 140 of about 7,599,404 (323)

Highly Robust Hydrogen Generation by Bioinspired Ir Complexes for Dehydrogenation of Formic Acid in Water: Experimental and Theoretical Mechanistic Investigations at Different pH

, 2015
Wan‐Hui Wang, Mehmed Z. Ertem, Shaoan Xu, Naoya Onishi, Yuichi Manaka, Yuki Suna, Hide Kambayashi, James T. Muckerman, Etsuko Fujita, Yuichiro Himeda   +9 more
openalex   +2 more sources

The promoter of the operon encoding the F₀F₁ ATPase of Streptococcus pneumoniae is inducible by pH [PDF]

, 2001
Antonio J. Martín-Galiano, María-José Ferrándiz, Adela G. de la Campa   +2 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Zeitgemässe Lehrkompetenzentwicklung

Zeitschrift für Hochschulentwicklung
Die Hochschullehre steht vor großen Herausforderungen: Digitalisierung, Bildungsexpansion und der Ruf nach guter, wissenschaftlich fundierter und gleichzeitig arbeitsmarktnaher Lehre verlangen nach neuen Ansätzen.
Marion Lehner, Angela Jochum, Benno Volk, Philip Barth, Samuel Krattenmacher   +4 more
doaj   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Influence of reverted austenite on static and dynamic mechanical properties of a PH 13-8 Mo maraging steel

, 2009
Ronald Schnitzer, Gerald A. Zickler, E. Lach, Helmut Clemens, Silvia Zinner, Thomas C. Lippmann, Harald Leitner   +6 more
openalex   +2 more sources

DIAGNOSTIC ANALYSIS OF THE COST PER UNIT OF PRODUCT [PDF]

This paper treats the methodology used in the product unit diagnostic analysis by entities where products are obtained in several subordinated entities with management autonomy.
Prof. Ioan Pană Ph. D, Prof. Viorica Pană Ph. D   +1 more
core  

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Biodegradability study and pH influence on growth and orientation of ZnO nanorods via aqueous solution process

, 2012
P. Suresh Kumar, Pradip Paik, A. Dhayal Raj, D. Mangalaraj, D. Nataraj, Aharon Gedanken, Seeram Ramakrishna   +6 more
openalex   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source