Fachspezifische Qualitätsprofile von Rechtschreibunterricht in Deutschland und der Schweiz
Im Rahmen der ländervergleichenden Studie „Professionelle Kompetenzen und Unterrichtshandeln von Primarlehrpersonen im Lernbereich Rechtschreibung“ wurden 43 Rechtschreiblektionen zur Doppelkonsonantenschreibung in den Klassen 3 bis 6 videografiert und ...
Maja Wiprächtiger +4 more
doaj +1 more source
Decoherence induced continuous pointer states [PDF]
We investigate the reduced dynamics in the Markovian approximation of an infinite quantum spin system linearly coupled to a phonon field at positive temperature. The achieved diagonalization leads to a selection of the continuous family of pointer states
Blanchard, Ph., Olkiewicz, R.
core +3 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
The human right to medicines [PDF]
This article considers the component of the right to the highest standard of health that relates to medicines, including essential medicines. Using the right-to-health analytical framework that has been developed in recent years, the first section ...
Hunt, PH, Khosla, R
core
X-ray observations and mass determinations in the cluster of galaxies Cl0024+17 [PDF]
We present a detailed analysis of the mass distribution in the rich and distant cluster of galaxies Cl0024+17. X-ray data come from both a deep ROSAT/HRI image of the field (Bohringer et al. 1999) and ASCA spectral data.
Bohringer, H. +5 more
core +3 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
A study of center vortices in SU(2) and SU(3) gauge theories [PDF]
We show how center vortices and Abelian monopoles both appear as local gauge ambiguities in the Laplacian Center gauge. Numerical results, for SU(2) and SU(3), support the view that the string tension obtained in the center-projected theory matches the ...
de Forcrand, Ph., Pepe, M.
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Tangential Large Scale Structure as a Standard Ruler: Curvature Parameters from Quasars [PDF]
Several observational analyses suggest that matter is spatially structured at $\approx 130h^{-1}Mpc$ at low redshifts. This peak in the power spectrum provides a standard ruler in comoving space which can be used to compare the local geometry at high and
Mamon, Gary A., Roukema, Boudewijn F.
core +3 more sources

