Results 61 to 70 of about 7,411,908 (274)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Praktiken der Differenzbearbeitung im Fachunterricht einer integrativen Schule der Sekundarstufe. Zur Überlagerung von Schulleistung, Peerkultur und Geschlecht

open access: yesGender, 2015
Der Beitrag geht der Frage nach, wie im Deutsch- und Mathematikunterricht einer integrativen achten Klasse einer nicht-gymnasialen Schulform Leistung konstruiert und von peerkulturellen, geschlechtsbezogenen Formen überlagert wird.
Tanja Sturm, Monika Wagner-Willi
doaj   +1 more source

Die ersten 1000: Computational Thinking als obligatorische Ausbildung für Primarschullehrpersonen in der Schweiz

open access: yesMedienPädagogik: Zeitschrift für Theorie und Praxis der Medienbildung, 2020
Die Umsetzung des Lehrplans 21, der mit dem Modul «Medien und Informatik» informatische Bildung (IB) in die Schweizer Primarschulen bringen wird, wirft wichtige Fragen auf: Insbesondere fragt sich, wie die Umsetzung gegen die bei vielen ...
Alexander Repenning   +2 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Finite-Element Analysis of Shear-off Failure of Keyed Dry Joints in Precast Concrete Segmental Bridges [PDF]

open access: yes, 2014
This article has been made available through the Brunel Open Access Publishing Fund.The structural behaviour of precast concrete segmental bridges is largely dependent on the behaviour of the joints between segments.
Giulio Alfano   +5 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

PENGEMBANGAN SMK MODEL UNTUK MASA DEPAN

open access: yesCakrawala Pendidikan: Jurnal Ilmiah Pendidikan, 2013
Abstrak: Praktik penyelenggaraan SMK di Indonesia saat ini menunjukkan kelemahan-kelemahan sebagai berikut: menyelenggarakan fungsi tunggal, yaitu menyiapkan siswa untuk bekerja, untuk menjadi karyawan, dan kurang menyiapkan untuk menjadi wirausahawan ...
Slamet PH PH
doaj   +1 more source

Aspects of (2+1) dimensional gravity: AdS3 asymptotic dynamics in the framework of Fefferman-Graham-Lee theorems [PDF]

open access: yes, 1999
Using the Chern-Simon formulation of (2+1) gravity, we derive, for the general asymptotic metrics given by the Fefferman-Graham-Lee theorems, the emergence of the Liouville mode associated to the boundary degrees of freedom of (2+1) dimensional anti de ...
Rooman, M., Spindel, Ph.
core   +1 more source

The "Cameo Principle" and the Origin of Scale-Free Graphs in Social Networks

open access: yes, 2003
We formulate a simple edge generation rule based on an inverse like mass action principle for random graphs over a structured vertex set. We show that under very weak assumptions on the structure generating distribution we obtain a scale free ...
Blanchard, Ph., Krueger, T.
core   +1 more source

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