Results 61 to 70 of about 7,599,404 (323)
On a weak solution of Einstein equations for expanding dust
, 2011 An expanding spherically symmetric dust cloud is considered in a framework of general relativity. Initial conditions leading to a shell-crossing singularity are chosen. The way to construct a weak solution for such a case is proposed.
Tegai, Sergey Ph.
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Die Wirksamkeit von Lehrer*innenfortbildung aus der Sicht der Fortbildner*innen
Herausforderung Lehrer*innenbildung, 2020 Dieser Beitrag thematisiert die Wirksamkeit von Lehrer*innenfortbildungen sowie wahrgenommene Erwartungen aus der Perspektive der Fortbildner*innen. Die spärliche Forschungslage zu diesem Thema führte zu der Projektidee, den Fokus der Forschung auf die ...
Isabel Wanitschek +3 more
doaj +1 more source
Nucleation kinetics of calcium oxalate monohydrate as a function of pH, magnesium, and osteopontin concentration quantified with droplet microfluidics [PDF]
, 2021 Fatma İbiş +7 more
openalex +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Journal of Experimental Orthopaedics, 2023 Purpose Robotic‐assisted total knee arthroplasty typically necessitates use of tracking pins, which can vary in diameter. Complications such as infections and fractures at the pin‐site have been observed, but clarification of the effect of pin diameter ...
Sohil S. Desai +7 more
doaj +1 more source
, 2006 Half-metallic Heusler alloys are amongst the most promising materials for future magnetoelectronic applications. We review some recent results on the electronic properties of these compounds.
Galanakis, I., Mavropoulos, Ph.
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Editorial 04/2024: Digitalität, Produktion, Verantwortung
MedienimpulseDigitalisierung und Digitalität haben sich als neue gesamtgesellschaftliche Phänomene etabliert und werden in der (medienpädagogischen) Fachliteratur richtigerweise als solche verhandelt und analysiert.
Alessandro Barberi +3 more
doaj +1 more source