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Phage Therapy for Antibiotic-Resistant Bacterial Infections.
Antibiotic resistance in bacterial pathogens presents a substantial threat to the control of infectious diseases. Development of new classes of antibiotics has slowed in recent years due to pressures of cost and market profitability, and there is a ...
G. Hatfull, R. Dedrick, R. Schooley
semanticscholar +1 more source
Treatment of infections caused by bacteria has become more complex due to the increasing number of bacterial strains that are resistant to conventional antimicrobial therapy. A highly promising alternative appears to be bacteriophage (phage) therapy, in which natural predators of bacteria, bacteriophages, play a role.
Marek Straka +2 more
openaire +3 more sources
Phage Therapy—Challenges, Opportunities and Future Prospects
The increasing drug resistance of bacteria to commonly used antibiotics creates the need to search for and develop alternative forms of treatment. Phage therapy fits this trend perfectly.
Beata Zalewska-Piątek
semanticscholar +1 more source
Formulations for Bacteriophage Therapy and the Potential Uses of Immobilization
The emergence of antibiotic-resistant pathogens is becoming increasingly problematic in the treatment of bacterial diseases. This has led to bacteriophages receiving increased attention as an alternative form of treatment.
Daniel Rosner, Jason Clark
doaj +1 more source
Antimicrobial alternatives such as nanoparticles are critically required to tackle bacterial infections, especially with the emerging threat of antibiotic resistance.
Nouran Rezk +5 more
doaj +1 more source
Regulations of phage therapy across the world
Phage therapy, a century-long treatment targeting bacterial infection, was widely abandoned after the clinical availability of antibiotics in the mid-20th century. However, the crisis of antimicrobial resistance today led to its revival in many countries.
Qimao Yang +3 more
semanticscholar +1 more source
Morphological, biological, and genomic characterization of Klebsiella pneumoniae phage vB_Kpn_ZC2
Background Bacteriophages (phages) are one of the most promising alternatives to traditional antibiotic therapies, especially against multidrug-resistant bacteria.
Mohamed S. Fayez +8 more
doaj +1 more source
The emergence and evolution of antibiotic-resistant bacteria is considered a public health concern. Salmonella is one of the most common pathogens that cause high mortality and morbidity rates in humans, animals, and poultry annually.
Abdallah S. Abdelsattar +5 more
doaj +1 more source
Background: With advances in sequencing technology and decreasing costs, the number of phage genomes that have been sequenced has increased markedly in the past decade.
Ryan Cook +9 more
semanticscholar +1 more source
Adapting a Phage to Combat Phage Resistance [PDF]
Phage therapy is becoming a widely recognized alternative for fighting pathogenic bacteria due to increasing antibiotic resistance problems. However, one of the common concerns related to the use of phages is the evolution of bacterial resistance against the phages, putatively disabling the treatment.
Mäkelä, Kati +5 more
openaire +6 more sources

