Results 81 to 90 of about 469,268 (356)

Induction of Mutations in a Bacterial Virus [PDF]

, 1953
In the course of experiments designed for other purposes a paradoxical observation was made: phage λ, inactivated by UV irradiation, when adsorbed onto sensitive bacteria was reactivated when a further dose of UV was given to the phage-bacterium ...
Weigle, J. J.
core  

Biomimetic hydroxyapatite nanocrystals are an active carrier for Salmonella bacteriophages [PDF]

, 2019
open access articlePurpose: The use of bacteriophages represents a valid alternative to conventional antimicrobial treatments, overcoming the widespread bacterial antibiotic resistance phenomenon.
Capparelli, Rosanna, Capuano, Federico, Contaldi, Felice, Della Ventura, Bartolomeo, Fulgione, Andrea, Giannini, Cinzia, Ianniello, Flora, Lelli, Marco, Papaianni, Marina, Pastore, Stella, Roveri, Norberto, Sgamma, Tiziana, Velotta, Raffaele   +12 more
core   +2 more sources

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Structural basis of Acinetobacter type IV pili targeting by an RNA virus

Nature Communications
Acinetobacters pose a significant threat to human health, especially those with weakened immune systems. Type IV pili of acinetobacters play crucial roles in virulence and antibiotic resistance.
Ran Meng, Zhongliang Xing, Jeng-Yih Chang, Zihao Yu, Jirapat Thongchol, Wen Xiao, Yuhang Wang, Karthik Chamakura, Zhiqi Zeng, Fengbin Wang, Ry Young, Lanying Zeng, Junjie Zhang   +12 more
doaj   +1 more source

Comparative transcriptomic and molecular biology analyses to explore potential immune responses to Vibrio parahaemolyticus challenge in Eriocheir sinensis

Frontiers in Cellular and Infection Microbiology
Vibrio parahaemolyticus is a significant pathogen affecting shrimp and crab farming, particularly strains carrying genes associated with acute hepatopancreatic necrosis syndrome. However, the immune response of Eriocheir sinensis to V.
Duanduan Chen, Duanduan Chen, Yunteng Xin, Yunteng Xin, Jian Teng, Xiaodong Zhao, Jianbiao Lu, Yubao Li, Hui Wang, Hui Wang   +9 more
doaj   +1 more source

Measuring the force ejecting DNA from phage [PDF]

, 2004
We discuss how a balance can be established between the force acting to eject DNA from viral capsids and the force resisting its entry into a colloidal suspension which mimics the host cell cytoplasm.
Castelnovo, M., Evilevitch, A., Gelbart, W. M., Knobler, C. M.   +3 more
core   +1 more source

Multimodal Actuation and Environment Adaptive Strategies of Bio‐Inspired Micro/Nanorobots in Precision Medicine

Advanced Robotics Research, EarlyView.
An introduction for multidrive and environment‐adaptive micro/nanorobotics: design and fabrication strategies, intelligent actuation, and their applications. Various intelligent actuation approaches—magnetic, acoustic, optical, chemical, and biological—can be synergistically designed to enhance flexibility and adaptive behavior for precision medicine ...
Aiqing Ma, Han Gong, Jiacheng Ouyang, Liqi Chen, Tianfang Kang, Yiran He, Guojun Huang, Sidi Zheng, Ting Yin, Hong Pan, Lintao Cai   +10 more
wiley   +1 more source

Green synthesis of silver and gold-doped zinc oxide nanocomposite with propolis extract for enhanced anticancer activity

Scientific Reports
Metal and metal oxide nanocomposites have unique properties and are promising for antibacterial and anticancer applications. In this work, we aimed to highlight the relationship between the biosynthesis ways of silver and gold-doped zinc oxide ...
Abdallah S. Abdelsattar, Aghapy Yermans Yakoup, Azza G. Kamel, Ayman El-Shibiny   +3 more
doaj   +1 more source

Experimental phage therapy of burn wound infection : difficult first steps [PDF]

, 2014
Antibiotic resistance has become a major public health problem and the antibiotics pipeline is running dry. Bacteriophages (phages) may offer an ‘innovative’ means of infection treatment, which can be combined or alternated with antibiotic therapy and ...
De Vos, Daniel, Jennes, Serge, Lavigne, Rob, Merabishvili, Maia, Pirnay, Jean Paul, Rose, Thomas, Vaneechoutte, Mario, Verbeken, Gilbert, Zizi, Martin   +8 more
core  

Dynamics of Bacteriophage Genome Ejection In Vitro and In Vivo

, 2010
Bacteriophages, phages for short, are viruses of bacteria. The majority of phages contain a double-stranded DNA genome packaged in a capsid at a density of ~500 mg/ml. This high density requires substantial compression of the normal B form helix, leading
Molineux, Ian J., Panja, Debabrata
core   +1 more source