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Targeted dual-receptor phage cocktail against Cronobacter sakazakii: insights into phage-host interactions and resistance mechanisms [PDF]

open access: yesFrontiers in Microbiology
IntroductionCronobacter sakazakii is a notorious foodborne pathogen, frequently contaminating powdered infant formula and causing life-threatening diseases in infants.
Seongok Kim   +9 more
doaj   +5 more sources

What Can We Learn from a Metagenomic Analysis of a Georgian Bacteriophage Cocktail? [PDF]

open access: yesViruses, 2015
Phage therapy, a practice widespread in Eastern Europe, has untapped potential in the combat against antibiotic-resistant bacterial infections. However, technology transfer to Western medicine is proving challenging. Bioinformatics analysis could help to
Henrike Zschach   +11 more
doaj   +14 more sources

Evaluating the effectiveness and safety of a novel phage cocktail as a biocontrol of Salmonella in biofilm, food products, and broiler chicken [PDF]

open access: yesFrontiers in Microbiology
Salmonella is a foodborne pathogen of animal and public health significance. Considering the disadvantages of antibiotics or chemical preservatives traditionally used to eliminate this pathogen, attention has shifted, in recent years, toward biocontrol ...
Narges Torkashvand   +10 more
doaj   +3 more sources

From Isolation to Application: Designing a Multi-Target Phage Cocktail for Bivalve Safety [PDF]

open access: yesMicroorganisms
Narrow host specificity and bacterial resistance often limit single-phage treatments. Phage cocktails address these challenges by expanding the host range, reducing resistance, and enhancing bacterial inactivation.
Pedro Costa   +3 more
doaj   +3 more sources

Effective reduction of Salmonella Enteritidis in broiler chickens using the UPWr_S134 phage cocktail [PDF]

open access: yesFrontiers in Microbiology, 2023
Salmonella is a poultry-associated pathogen that is considered one of the most important zoonotic bacterial agents of contaminated food of animal origin including poultry products.
Marta Kuźmińska-Bajor   +8 more
doaj   +3 more sources

Multireceptor phage cocktail against Salmonella enterica to circumvent phage resistance. [PDF]

open access: yesMicrolife
Non-Typhoidal Salmonella (NTS) is one of the most common food-borne pathogens worldwide, with poultry products being the major vehicle for pathogenesis in humans.
Martinez-Soto CE   +5 more
europepmc   +6 more sources

A Klebsiella-phage cocktail to broaden the host range and delay bacteriophage resistance both in vitro and in vivo [PDF]

open access: yesnpj Biofilms and Microbiomes
Bacteriophages (phages), viruses capable of infecting and lysing bacteria, are a promising alternative for treating infections from hypervirulent, antibiotic-resistant pathogens like Klebsiella pneumoniae, though narrow host range and phage resistance ...
Huanchang Chen   +9 more
doaj   +3 more sources

Systemic Effects of a Phage Cocktail on Healthy Weaned Piglets. [PDF]

open access: yesBiology (Basel)
Simple Summary Bacteriophages (phages) are viruses specifically infecting bacteria, and have been considered as a prospective substitute for antibiotics.
Liu Y, Lin Y, Zhu W.
europepmc   +5 more sources

The Use of Phage Cocktail and Various Antibacterial Agents in Combination to Prevent the Emergence of Phage Resistance [PDF]

open access: yesAntibiotics, 2023
Bacterial food poisoning cases due to Salmonella and E. coli O157:H7 have been linked with the consumption of a variety of food products, threatening public health around the world.
Hoang Minh Duc   +5 more
doaj   +3 more sources

Rational design of a hospital-specific phage cocktail to treat Enterobacter cloacae complex infections. [PDF]

open access: yesNat Microbiol
The Alfred Hospital in Melbourne, Australia, has reported an ongoing outbreak of infections caused by multidrug-resistant Enterobacter cloacae complex (ECC). Phage therapy is a promising strategy to treat antimicrobial-resistant infections. Utilizing the
Subedi D   +10 more
europepmc   +2 more sources

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