A method for generation phage cocktail with great therapeutic potential. [PDF]
BACKGROUND: Bacteriophage could be an alternative to conventional antibiotic therapy against multidrug-resistant bacteria. However, the emergence of resistant variants after phage treatment limited its therapeutic application.
Jingmin Gu +11 more
doaj +2 more sources
Effective reduction of Salmonella Enteritidis in broiler chickens using the UPWr_S134 phage cocktail [PDF]
Salmonella is a poultry-associated pathogen that is considered one of the most important zoonotic bacterial agents of contaminated food of animal origin including poultry products.
Marta Kuźmińska-Bajor +8 more
doaj +2 more sources
Efficacy and Safety of a Bovine-Associated Staphylococcus aureus Phage Cocktail in a Murine Model of Mastitis [PDF]
Overuse of antibiotics is a major problem in the treatment of bovine mastitis, and antibiotic treatment is frequently non-curative, thus alternative treatments are necessary.
Koen Breyne +11 more
doaj +2 more sources
Use of a Specific Phage Cocktail for Soft Rot Control on Ware Potatoes: A Case Study
Using bacteriophages (bacterial viruses) to control pathogenic bacteria is a promising approach in horticulture. However, the application of this strategy in real conditions requires compliance with particular technological and environmental restraints ...
Eugenia N. Bugaeva +6 more
doaj +3 more sources
Systemic Effects of a Phage Cocktail on Healthy Weaned Piglets [PDF]
Numerous studies have demonstrated that bacteriophages (phages) can effectively treat intestinal bacterial infections. However, research on the impact of phages on overall body health once they enter the intestine is limited.
Weiyun Zhu, Yan Lin
exaly +3 more sources
Impact of a single phage and a phage cocktail application in broilers on reduction of Campylobacter jejuni and development of resistance. [PDF]
Campylobacteriosis is currently the most frequent foodborne zoonosis in many countries. One main source is poultry. The aim of this study was to enhance the knowledge about the potential of bacteriophages in reducing colonization of broilers with ...
Samuel Fischer +3 more
doaj +2 more sources
Genetic basis of phage-host interaction: Towards effective phage therapy of non-typhoidal Salmonella
Non-typhoidal Salmonella (NTS) have adapted to cause invasive illness in humans. Bacteria have developed MDR against current antibiotics. Bacteriophage therapy is the hope for bacterial treatment however one of the key limitations is the limited host ...
Mohammed, M.
core +4 more sources
The rapid emergence of phage-resistant bacterial mutants is a major challenge for phage therapy. Phage cocktails have been considered one approach to mitigate this issue.
Dongyang Gao +9 more
doaj +1 more source
A Novel Phage Cocktail Therapy of the Urinary Tract Infection in a Mouse Model [PDF]
Escherichia coli (E. coli) is a major bacterial pathogen associated with many cases of serious infections, such as urinary tract infections (UTI) and meningitis intestinal.
B Mijbel Ali +3 more
doaj +1 more source
Phage Cocktail Designed for Wastewater Bioremediation Has Limited Effect on Crustacean Filtrator Microbiome Diversity and Health. [PDF]
In this study we investigated the impact of a phage cocktail on Daphnia magna microbiome and the life-history parameters. A mixture of four phages able to infect strains of Klebsiella pneumoniae, Enterobacter sp.
Grabska M +4 more
europepmc +2 more sources

