The Use of Phage Cocktail and Various Antibacterial Agents in Combination to Prevent the Emergence of Phage Resistance [PDF]
Antibiotics, 2023 Bacterial food poisoning cases due to Salmonella and E. coli O157:H7 have been linked with the consumption of a variety of food products, threatening public health around the world.
Hoang Minh Duc +5 more
doaj +4 more sources
A method for generation phage cocktail with great therapeutic potential. [PDF]
PLoS ONE, 2012 BACKGROUND: Bacteriophage could be an alternative to conventional antibiotic therapy against multidrug-resistant bacteria. However, the emergence of resistant variants after phage treatment limited its therapeutic application.
Jingmin Gu +11 more
doaj +4 more sources
Frontiers in Microbiology, 2020 With the emergence of multidrug-resistant and extensively drug-resistant bacterial pathogens, phage therapy and other alternative or additional therapeutic modalities are receiving resurgent attention.
Wei Shen, Ｑian Chen, Xuesong He
exaly +3 more sources
Effective reduction of Salmonella Enteritidis in broiler chickens using the UPWr_S134 phage cocktail [PDF]
Frontiers in Microbiology, 2023 Salmonella is a poultry-associated pathogen that is considered one of the most important zoonotic bacterial agents of contaminated food of animal origin including poultry products.
Marta Kuźmińska-Bajor +8 more
doaj +2 more sources
Systemic Effects of a Phage Cocktail on Healthy Weaned Piglets [PDF]
BiologyNumerous studies have demonstrated that bacteriophages (phages) can effectively treat intestinal bacterial infections. However, research on the impact of phages on overall body health once they enter the intestine is limited. This study utilized weaned piglets as subjects to evaluate the systemic effects of an orally administered phage cocktail on ...
Yan Lin, Weiyun Zhu, Zhu Weiyun
exaly +5 more sources
Broad-spectrum phage cocktail targeting Campylobacter improves survival in Galleria mellonella, a bridging host model for poultry biocontrol [PDF]
Frontiers in MicrobiologyCampylobacter jejuni and Campylobacter coli are the main agents of campylobacteriosis, a globally prevalent foodborne illness predominantly linked to the consumption of contaminated poultry products.
Estibaliz Ruiz-Santamaría +5 more
doaj +2 more sources
Evaluating the effectiveness and safety of a novel phage cocktail as a biocontrol of Salmonella in biofilm, food products, and broiler chicken [PDF]
Frontiers in MicrobiologySalmonella is a foodborne pathogen of animal and public health significance. Considering the disadvantages of antibiotics or chemical preservatives traditionally used to eliminate this pathogen, attention has shifted, in recent years, toward biocontrol ...
Narges Torkashvand +10 more
doaj +2 more sources
From Isolation to Application: Designing a Multi-Target Phage Cocktail for Bivalve Safety [PDF]
MicroorganismsNarrow host specificity and bacterial resistance often limit single-phage treatments. Phage cocktails address these challenges by expanding the host range, reducing resistance, and enhancing bacterial inactivation.
Pedro Costa +3 more
doaj +2 more sources
Precision Phage Cocktail Targeting Surface Appendages for Biocontrol of Salmonella in Cold-Stored Foods [PDF]
AntibioticsSalmonella enterica is a major food-borne pathogen causing food poisoning. The use of bacteriophages as alternative biocontrol agents has gained renewed interest due to the rising issue of antibiotic-resistant bacteria.
Seongok Kim +4 more
doaj +2 more sources
A Klebsiella-phage cocktail to broaden the host range and delay bacteriophage resistance both in vitro and in vivo [PDF]
npj Biofilms and MicrobiomesBacteriophages (phages), viruses capable of infecting and lysing bacteria, are a promising alternative for treating infections from hypervirulent, antibiotic-resistant pathogens like Klebsiella pneumoniae, though narrow host range and phage resistance ...
Huanchang Chen +9 more
doaj +2 more sources