Results 21 to 30 of about 102,405 (155)

Bacteriophages Combined With Subtherapeutic Doses of Flucloxacillin Act Synergistically Against Staphylococcus aureus Experimental Infective Endocarditis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background The potential of phage therapy for the treatment of endovascular Staphylococcus aureus infections remains to be evaluated. Methods and Results The efficacy of a phage cocktail combining Herelleviridae phage vB_SauH_2002 and Podoviriae phage 66
Jonathan Save, Yok‐Ai Que, José M. Entenza, Camille Kolenda, Frédéric Laurent, Grégory Resch   +5 more
doaj   +1 more source

Multireceptor phage cocktail against Salmonella enterica to circumvent phage resistance. [PDF]

Microlife
Non-Typhoidal Salmonella (NTS) is one of the most common food-borne pathogens worldwide, with poultry products being the major vehicle for pathogenesis in humans.
Martinez-Soto CE, McClelland M, Kropinski AM, Lin JT, Khursigara CM, Anany H.   +5 more
europepmc   +3 more sources

Development of a Bacteriophage Cocktail to Constrain the Emergence of Phage-Resistant Pseudomonas aeruginosa

Frontiers in Microbiology, 2020
With the emergence of multidrug-resistant and extensively drug-resistant bacterial pathogens, phage therapy and other alternative or additional therapeutic modalities are receiving resurgent attention.
Yuhui Yang, Wei Shen, Qiu Zhong, Qian Chen, Xuesong He, Jonathon L. Baker, Kun Xiong, Xiaoling Jin, Jing Wang, Fuquan Hu, Shuai Le   +10 more
doaj   +1 more source

Isolation and chacterisation of Klebsiella phages for phage therapy [PDF]

, 2021
Klebsiella is a clinically important pathogen causing a variety of antimicrobial resistant infections, in both community and nosocomial settings, particularly pneumonia, urinary tract infection and septicaemia.
Gannon, Lucy, Jameson, Eleanor, Trevor Lithgow (105055), Townsend, Eleanor, George Muscatt (10651649), Dunstan, Rhys, Townsend, Eleanor M, Eleanor Jameson (7327196), Hari Sapkota (10651655), Saija J Kiljunen (10651658), Lithgow, Trevor, Lucy Kelly (10651643), Sapkota, Hari, Eleanor M Townsend (10651640), Kiljunen, Saija J, Skurnik, Mikael, Michniewski, Slawomir, Kiljunen, Saija J., Rhys Dunstan (10651652), Slawomir Michniewski (7741364), Kelly, Lucy, Anna Kolsi (10651661), Mikael Skurnik (53234), Kolsi, Anna, Andrew D Millard (8411877), Millard, Andrew D., Millard, Andrew D, Lucy Gannon (10651646), Muscatt, George   +28 more
core   +1 more source

A Method to Determine the Efficacy of a Commercial Phage Preparation against Uropathogens in Urine and Artificial Urine Determined by Isothermal Microcalorimetry

Microorganisms, 2022
Background: Urinary tract infections are commonly encountered and often treated with antibiotics. However, the inappropriate use of the latter has led to the appearance of resistant strains.
Aurelia Pahnita Sigg, Max Mariotti, Anabel E. Grütter, Tecla Lafranca, Lorenz Leitner, Gernot Bonkat, Olivier Braissant   +6 more
doaj   +1 more source

Characterization of 29 newly isolated bacteriophages as a potential therapeutic agent against IMP-6-producing Klebsiella pneumoniae from clinical specimens

Microbiology Spectrum, 2023
Carbapenemase-producing Enterobacteriaceae (CPE) are one of the most detrimental species of antibiotic-resistant bacteria globally. Phage therapy has emerged as an effective strategy for the treatment of CPE infections.
Kohei Kondo, Satoshi Nakano, Junzo Hisatsune, Yo Sugawara, Michiyo Kataoka, Shizuo Kayama, Motoyuki Sugai, Mitsuoki Kawano   +7 more
doaj   +1 more source

Exploring the Benefits of Metal Ions in Phage Cocktail for the Treatment of Methicillin-Resistant Staphylococcus aureus (MRSA) Infection

Infection and Drug Resistance, 2022
Xinxin Li,1– 3 Yibao Chen,1– 3 Shuang Wang,1– 3 Xiaochao Duan,1– 3 Fenqiang Zhang,1– 3 Aizhen Guo,1– 3 Pan Tao,1– 3 Huanchun Chen,1– 3 Xiangmin Li,1– 3 Ping Qian1– 3 1State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University ...
Li X, Chen Y, Wang S, Duan X, Zhang F, Guo A, Tao P, Chen H, Li X, Qian P   +9 more
doaj  

Liposome Entrapment of Bacteriophages Improves Wound Healing in a Diabetic Mouse MRSA Infection

Frontiers in Microbiology, 2018
Diabetic populations are more prone to developing wound infections which results in poor and delayed wound healing. Infection with drug resistant organisms further worsen the situation, driving searches for alternative treatment approaches such as phage ...
Sanjay Chhibber, Jasjeet Kaur, Sandeep Kaur   +2 more
doaj   +1 more source

Phage Therapy vs. the Use of Antibiotics in the Treatment of Salmonella-Infected Chickens: Comparison of Effects on Hematological Parameters and Selected Biochemical Markers

Antibiotics, 2022
Previous studies indicated that the use of a phage cocktail, composed of bacteriophages vB_SenM-2 and vB_Sen-TO17, is effective in killing cells of Salmonella enterica serovars Typhimurium and Enteritidis in vitro and in the Galleria mellonella animal ...
Łukasz Grabowski, Grzegorz Węgrzyn, Alicja Węgrzyn, Magdalena Podlacha   +3 more
doaj   +1 more source

Development of an Anti-Acinetobacter baumannii Biofilm Phage Cocktail: Genomic Adaptation to the Host [PDF]

, 2022
The need for alternatives to antibiotic therapy due to the emergence of multidrug resistant bacteria (MDR), such as the nosocomial pathogen Acinetobacter baumannii, has led to the recovery of phage therapy.
Oliveira, Hugo, Azeredo, J, Pascual, Á., Azeredo, J., López Sánchez, María Victoria, Fernández-Cuenca, Felipe, Fernández-Cuenca, F., Oliverira, H., Pascual, A, Bleriot, Inés, Fernádez-Cuenca, F., Ortiz-Cartagena, Concha, Blasco, L, Fernandez-Cuenca, F, Bleriot, I., Pacios, Olga, Oliveira, H, Ortiz-Cartagena, C, Fernández-García, Laura, Pascual, Álvaro, Pacios, O, Martínez-Martínez, L., Fernández-García, L., Gonzalez de Aledo, M, Tomás, M., González de Aledo, Manuel, González de Aledo, M., Pachón, J., Martínez-Martínez, Luis, Lopez, M, Pachon, J, Oliveira, H., Tomás, María, Pachón, Jerónimo, López-Díaz, María, Fernandez-Garcia, L, Blasco, L., Martinez-Martinez, L, Bleriot, I, Tomas, M, Pacios, O., Blasco, Lucía, Ortiz-Cartagena, C., López, M.   +43 more
core   +1 more source