Results 21 to 30 of about 17,973 (167)

Phage Cocktail Alleviates Bacterial Canker of Kiwifruit by Modulating Bacterial Community Structure in Field Trial [PDF]

Microorganisms
Bacterial canker of kiwifruit is the most destructive bacterial disease caused by Pseudomonas syringae pv. actinidiae. Bacteriophages are regarded as promising biocontrol agents against kiwifruit bacterial pathogens due to their exceptional host ...
Ran Hu, Xiaohan Xu, Yajun Jia, Cancan Zhu, Lin Wang, Minxin Song, Qian Xu, Mian Xia, Xiaoqing He, Yi Jin   +9 more
doaj   +2 more sources

Efficiency, cytotoxicity, and survivability evaluation of Salmonella phage cocktail against Salmonella derived from broiler sources [PDF]

Veterinary World
Background and Aim: Salmonella is a leading cause of foodborne illnesses worldwide, often linked to poultry products. Antibiotic resistance among Salmonella strains has increased the need for alternative decontamination strategies, such as bacteriophage (
Wattana Pelyuntha, Thamonwan Narkpao, David Yembilla Yamik, Pichamon Kiatwuthinon, Arsooth Sanguankiat, Attawit Kovitvadhi, Kitiya Vongkamjan   +6 more
doaj   +2 more sources

Targeted dual-receptor phage cocktail against Cronobacter sakazakii: insights into phage-host interactions and resistance mechanisms [PDF]

Frontiers in Microbiology
IntroductionCronobacter sakazakii is a notorious foodborne pathogen, frequently contaminating powdered infant formula and causing life-threatening diseases in infants.
Seongok Kim, Bokyung Son, Yeran Kim, Yeran Kim, Hyeongsoon Kim, Gahyeon Nam, Hakdong Shin, Sangryeol Ryu, Sangryeol Ryu, Sangryeol Ryu   +9 more
doaj   +2 more sources

Phage Cocktails Constrain the Growth of Enterococcus [PDF]

mSystems, 2022
Due to the rise in antibiotic resistance, Enterococcus infections are a major health crisis that requires the development of alternative therapies. Phage therapy offers an alternative to antibiotics and has shown promise in both in vitro and early clinical studies.
Stephen Wandro, Pooja Ghatbale, Hedieh Attai, Clark Hendrickson, Cyril Samillano, Joy Suh, Sage J. B. Dunham, David T. Pride, Katrine Whiteson   +8 more
openaire   +4 more sources

Systematic analysis of putative phage-phage interactions on minimum-sized phage cocktails [PDF]

Scientific Reports, 2022
AbstractThe application of bacteriophages as antibacterial agents has many benefits in the “post-antibiotic age”. To increase the number of successfully targeted bacterial strains, phage cocktails, instead of a single phage, are commonly formulated. Nevertheless, there is currently no consensus pipeline for phage cocktail development.
Molina, Felipe, Menor-Flores, Manuel, Fernández Llamas, Lucía, Vega-Rodríguez, Miguel Ángel, García Suárez, María Pilar   +4 more
openaire   +4 more sources

Fitness Trade-Offs in Phage Cocktail-Resistant Salmonella enterica Serovar Enteritidis Results in Increased Antibiotic Susceptibility and Reduced Virulence

Microbiology Spectrum, 2022
The rapid emergence of phage-resistant bacterial mutants is a major challenge for phage therapy. Phage cocktails have been considered one approach to mitigate this issue.
Dongyang Gao, Hongyue Ji, Linkang Wang, Xinxin Li, Dayue Hu, Junna Zhao, Shuang Wang, Pan Tao, Xiangmin Li, Ping Qian   +9 more
doaj   +1 more source

A Novel Phage Cocktail Therapy of the Urinary Tract Infection in a Mouse Model [PDF]

Archives of Razi Institute, 2021
Escherichia coli (E. coli) is a major bacterial pathogen associated with many cases of serious infections, such as urinary tract infections (UTI) and meningitis intestinal.
B Mijbel Ali, S. A Gatea Kaabi, M. A Al-Bayati, H. K Musafer   +3 more
doaj   +1 more source

Bacteriophages Combined With Subtherapeutic Doses of Flucloxacillin Act Synergistically Against Staphylococcus aureus Experimental Infective Endocarditis

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background The potential of phage therapy for the treatment of endovascular Staphylococcus aureus infections remains to be evaluated. Methods and Results The efficacy of a phage cocktail combining Herelleviridae phage vB_SauH_2002 and Podoviriae phage 66
Jonathan Save, Yok‐Ai Que, José M. Entenza, Camille Kolenda, Frédéric Laurent, Grégory Resch   +5 more
doaj   +1 more source

A New Pipeline for Designing Phage Cocktails Based on Phage-Bacteria Infection Networks [PDF]

Frontiers in Microbiology, 2021
In recent years, the spread of antibiotic-resistant bacteria and efforts to preserve food microbiota have induced renewed interest in phage therapy. Phage cocktails, instead of a single phage, are commonly used as antibacterial agents since the hosts are unlikely to become resistant to several phages simultaneously. While the spectrum of activity might
Felipe Molina, Alfredo Simancas, Manuel Ramírez, Rafael Tabla, Isidro Roa, José Emilio Rebollo   +5 more
openaire   +3 more sources

Phage cocktail powder for Pseudomonas aeruginosa respiratory infections

International Journal of Pharmaceutics, 2021
Phage cocktail broadens the host range compared with a single phage and minimizes the development of phage-resistant bacteria thereby promoting the long-term usefulness of inhaled phage therapy. In this study, we produced a phage cocktail powder by spray drying three Pseudomonas phages PEV2 (podovirus), PEV1 and PEV20 (both myovirus) with lactose (80 ...
Li, Mengyu, Chang, Rachel Yoon Kyung, Lin, Yu, Morales, Sandra, Kutter, Elizabeth, Chan, Hak-Kim   +5 more
openaire   +5 more sources