Results 1 to 10 of about 49,769 (120)

Human β-Defensin 2 and Its Postulated Role in Modulation of the Immune Response

Cells, 2021
Studies described so far suggest that human β-defensin 2 is an important protein of innate immune response which provides protection for the human organism against invading pathogens of bacterial, viral, fungal, as well as parasitical origin. Its pivotal
Martyna Cieślik, Natalia Bagińska, Andrzej Górski, Ewa Jończyk-Matysiak   +3 more
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Animal Models in the Evaluation of the Effectiveness of Phage Therapy for Infections Caused by Gram-Negative Bacteria from the ESKAPE Group and the Reliability of Its Use in Humans

Microorganisms, 2021
The authors emphasize how extremely important it is to highlight the role played by animal models in an attempt to determine possible phage interactions with the organism into which it was introduced as well as to determine the safety and effectiveness ...
Martyna Cieślik, Natalia Bagińska, Andrzej Górski, Ewa Jończyk-Matysiak   +3 more
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The Role of Antibiotic Resistant A. baumannii in the Pathogenesis of Urinary Tract Infection and the Potential of Its Treatment with the Use of Bacteriophage Therapy

Antibiotics, 2021
Acinetobacter baumannii are bacteria that belong to the critical priority group due to their carbapenems and third generation cephalosporins resistance, which are last-chance antibiotics.
Natalia Bagińska, Martyna Cieślik, Andrzej Górski, Ewa Jończyk-Matysiak   +3 more
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Biological Properties of 12 Newly Isolated Acinetobacter baumannii-Specific Bacteriophages

Viruses, 2023
Infections with the opportunistic Gram-negative bacterium Acinetobacter baumannii pose a serious threat today, which is aggravated by the growing problem of multi-drug resistance among bacteria, caused by the overuse of antibiotics.
Natalia Bagińska, Marek Adam Harhala, Martyna Cieślik, Filip Orwat, Beata Weber-Dąbrowska, Krystyna Dąbrowska, Andrzej Górski, Ewa Jończyk-Matysiak   +7 more
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Immune Response to Therapeutic Staphylococcal Bacteriophages in Mammals: Kinetics of Induction, Immunogenic Structural Proteins, Natural and Induced Antibodies

Frontiers in Immunology, 2021
Bacteriophages are able to affect the human immune system. Phage-specific antibodies are considered as major factors shaping phage pharmacokinetics and bioavailability.
Zuzanna Kaźmierczak, Zuzanna Kaźmierczak, Joanna Majewska, Paulina Miernikiewicz, Ryszard Międzybrodzki, Ryszard Międzybrodzki, Sylwia Nowak, Marek Harhala, Dorota Lecion, Weronika Kęska, Barbara Owczarek, Jarosław Ciekot, Marek Drab, Paweł Kędzierski, Marta Mazurkiewicz-Kania, Andrzej Górski, Krystyna Dąbrowska   +16 more
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Bacteriophages and antibiotic interactions in clinical practice: what we have learned so far

Journal of Biomedical Science, 2022
Bacteriophages (phages) may be used as an alternative to antibiotic therapy for combating infections caused by multidrug-resistant bacteria. In the last decades, there have been studies concerning the use of phages and antibiotics separately or in ...
Marzanna Łusiak-Szelachowska, Ryszard Międzybrodzki, Zuzanna Drulis-Kawa, Kathryn Cater, Petar Knežević, Cyprian Winogradow, Karolina Amaro, Ewa Jończyk-Matysiak, Beata Weber-Dąbrowska, Justyna Rękas, Andrzej Górski   +10 more
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How Interest in Phages Has Bloomed into a Leading Medical Research Activity in Poland

Viruses, 2022
Poland has a leading position in phage therapy, as reflected by the number of patients treated and relevant publications in quality journals. The Institute of Immunology and Experimental Therapy of the Polish Academy of Sciences was established by Ludwik
Maciej Żaczek, Andrzej Górski, Andrzej Grzybowski, Edyta Pasternak, Beata Weber-Dąbrowska, Ryszard Międzybrodzki   +5 more
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Bronisława Fejgin (1883–1943): Forgotten Important Contributor to International Microbiology and Phage Therapy

Antibiotics, 2021
Bronisława Brandla Fejgin was a Polish-born Jewish female physician. Among Fejgin’s numerous articles in the field of microbiology, her later work was almost entirely devoted to phage research.
Andrzej Grzybowski, Maciej Żaczek, Andrzej Górski, Beata Weber-Dąbrowska, Ryszard Międzybrodzki   +4 more
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Do Anti-Phage Antibodies Persist after Phage Therapy? A Preliminary Report

Antibiotics, 2022
Phages are immunogenic and may evoke an immune response following their administration. Consequently, patients undergoing phage therapy (PT) produce phage-neutralizing serum antibodies.
Marzanna Łusiak-Szelachowska, Ryszard Międzybrodzki, Paweł Rogóż, Beata Weber-Dąbrowska, Maciej Żaczek, Andrzej Górski   +5 more
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A Thorough Synthesis of Phage Therapy Unit Activity in Poland—Its History, Milestones and International Recognition

Viruses, 2022
The year 2020 marked 15 years of the Phage Therapy Unit in Poland, the inception of which took place just one year after Poland’s accession to the European Union (2004).
Maciej Żaczek, Andrzej Górski, Beata Weber-Dąbrowska, Sławomir Letkiewicz, Wojciech Fortuna, Paweł Rogóż, Edyta Pasternak, Ryszard Międzybrodzki   +7 more
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