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Recent advances in bacteriophage-based therapeutics: Insight into the post-antibiotic era
Acta Pharmaceutica Sinica B, 2022 Antibiotic resistance is one of the biggest threats to global health, as it can make the treatment of bacterial infections in humans difficult owing to their high incidence rate, mortality, and treatment costs.
Hao Ling +5 more
doaj +1 more source
Genomewide Patterns of Substitution in Adaptively Evolving Populations of the RNA Bacteriophage MS2 [PDF]
, 2009 Experimental evolution of bacteriophage provides a powerful means of studying the genetics of adaptation, as every substitution contributing to adaptation can be identified and characterized.
Charlesworth, Brian +1 more
core +1 more source
The Future of Bacteriophage Therapy Will Promote Antimicrobial Susceptibility
mSystems, 2021 Rising antimicrobial resistance severely limits efforts to treat infections and is a cause for critical concern. Renewed interest in bacteriophage therapy has advanced understanding of the breadth of species capable of targeting bacterial antimicrobial ...
Olivia Williams Barber +4 more
doaj +1 more source
Phage Therapy: Towards a Successful Clinical Trial
Antibiotics, 2020 While phage therapy carried out as compassionate use (experimental therapy) has recently flourished, providing numerous case reports of supposedly healed patients, clinical trials aiming to formally prove their value in accord with current regulatory ...
Andrzej Górski +2 more
doaj +1 more source
Novel bacteriophages containing a genome of another bacteriophage within their genomes [PDF]
, 2012 The work was funded by the Scottish Government’s Rural and Environment Science and Analytical Services (RESAS) DivisionA novel bacteriophage infecting Staphylococus pasteuri was isolated during a screen for phages in Antarctic soils.
Makarova Kira S. +28 more
core +1 more source
Scientific ReportsAcinetobacter baumannii is currently a serious threat to human health, especially to people with immunodeficiency as well as patients with prolonged hospital stays and those undergoing invasive medical procedures.
Natalia Bagińska +8 more
doaj +1 more source
Taking Bacteriophage Therapy Seriously: A Moral Argument [PDF]
, 2014 The excessive and improper use of antibiotics has led to an increasing incidence of bacterial resistance. In Europe the yearly number of infections caused by multidrug resistant bacteria is more than 400.000, each year resulting in 25.000 attributable ...
Gorski, Andrzej +8 more
core +2 more sources
Pathogens, 2020 Phage therapy has emerged as a potential novel treatment of sepsis for which no decisive progress has been achieved thus far. Obviously, phages can help eradicate local bacterial infection and bacteremia that may occur in a syndrome.
Andrzej Górski +2 more
doaj +1 more source
Adsorption of MS2 bacteriophage on ultrafiltration membrane laboratory equipments [PDF]
, 2010 Virus adsorption has been quantified (i) on different materials including various containers made of glass, plastic or stainless steel and hollow fiber membranes made of polyethersulfone, polysulfone, PVDF or cellulose acetate (with two configurations ...
Causserand, Christel +3 more
core +1 more source
Persistence of bacteriophage T4 in a starved Escherichia coli culture: evidence for the presence of phage subpopulations. [PDF]
, 2011 Bacteriophage T4 is able to adjust its development to the growth parameters of the host cell. Here, we present evidence for the production of two different subpopulations of phage particles, which differ in their ability to infect starved Escherichia ...
Wiczk, Aleksandra +5 more
core +1 more source