Bacteriophage therapy - cooked goose or Phoenix rising? [PDF]
, 2008 Recent animal and human trials of bacteriophage therapy have demonstrated its potential to alleviate bacterial diseases, both in internal and in external applications. The regulatory requirements are becoming clearer as more examples are presented.
Spencer, Janice +3 more
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Circulation of Fluorescently Labelled Phage in a Murine Model
Viruses, 2021 Interactions between bacteriophages and mammals strongly affect possible applications of bacteriophages. This has created a need for tools that facilitate studies of phage circulation and deposition in tissues.
Zuzanna Kaźmierczak +4 more
doaj +1 more source
The Presence of Bacteriophages in the Human Body: Good, Bad or Neutral?
Microorganisms, 2020 The presence of bacteriophages (phages) in the human body may impact bacterial microbiota and modulate immunity. The role of phages in human microbiome studies and diseases is poorly understood.
Marzanna Łusiak-Szelachowska +4 more
doaj +1 more source
The superimmunity gene sim of bacteriophage P1 causes superinfection exclusion [PDF]
, 1989 Kliem M, Dreiseikelmann B. The superimmunity gene sim of bacteriophage P1 causes superinfection exclusion. Virology. 1989;171(2):350-355.Previous work has shown that the sim gene of bacteriophage P1, if cloned into a multicopy vector, confers immunity ...
Dreiseikelmann, Brigitte, Kliem, Manfred
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What Are the Potential Benefits of Using Bacteriophages in Periodontal Therapy?
Antibiotics, 2022 Periodontitis, which may result in tooth loss, constitutes both a serious medical and social problem. This pathology, if not treated, can contribute to the development of, among others, pancreatic cancer, cardiovascular diseases or Alzheimer’s disease ...
Jan Kowalski +4 more
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Frontiers in Microbiology, 2020 Although phage discovery is an unquestionable merit of the English bacteriologist Frederick W. Twort and the Canadian–French microbiologist Félix d’Hérelle, who both discovered phages over 100 years ago, the Polish history of phage studies also dates ...
Maciej Żaczek +8 more
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Cloning, sequencing, and overexpression of gene 16 of salmonella bacteriophage P22 [PDF]
, 1992 Umlauf B, Dreiseikelmann B. Cloning, sequencing, and overexpression of gene 16 of salmonella bacteriophage P22. Virology. 1992;188(2):495-501.It has been suggested that gene product 16 of bacteriophage P22 forms a pore for DNA transfer and/or that it ...
Dreiseikelmann, Brigitte +1 more
core +1 more source
Sequencing and analysis of the DNA genome of the temperate bacteriophage Aa[Phi]23 of "Actinobacillus actinomycetemcomitans" [PDF]
, 2005 The entire genomic sequence of the AaΦ23 bacteriophage is presented. Its size is 43,033 bp and it has an overall molar G+C content of 41mol%. 57 potential open reading frames (ORFs) were identified.
Resch, Grégory
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When bacteriophages encounter macrophages during their journey through the human body
Frontiers in Cellular and Infection MicrobiologyThe increasing problem of antibiotic resistance is one of the most significant threats to global public health, contributing to higher mortality rates, prolonged hospitalizations, and rising healthcare costs.
Martyna Cieślik +5 more
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Phage-Phagocyte Interactions and Their Implications for Phage Application as Therapeutics
Viruses, 2017 Phagocytes are the main component of innate immunity. They remove pathogens and particles from organisms using their bactericidal tools in the form of both reactive oxygen species and degrading enzymes—contained in granules—that are potentially toxic ...
Ewa Jończyk-Matysiak +6 more
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