Results 11 to 20 of about 48,920 (278)
Taking Bacteriophage Therapy Seriously: A Moral Argument [PDF]
BioMed Research International, 2014 The excessive and improper use of antibiotics has led to an increasing incidence of bacterial resistance. In Europe the yearly number of infections caused by multidrug resistant bacteria is more than 400.000, each year resulting in 25.000 attributable deaths. Few new antibiotics are in the pipeline of the pharmaceutical industry.
Gilbert Verbeken +8 more
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Bacteriophage Therapy: Discovery, Development, and FDA Approval Pathways. [PDF]
Pharmaceuticals (Basel)The escalating global crisis of antimicrobial resistance, responsible for approximately 1.27 million deaths in 2019, has catalyzed renewed interest in bacteriophage therapy as a viable therapeutic alternative.
Niazi SK.
europepmc +2 more sources
How Interest in Phages Has Bloomed into a Leading Medical Research Activity in Poland
Viruses, 2022 Poland has a leading position in phage therapy, as reflected by the number of patients treated and relevant publications in quality journals. The Institute of Immunology and Experimental Therapy of the Polish Academy of Sciences was established by Ludwik
Maciej Żaczek +5 more
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Antibiotics, 2021 Bronisława Brandla Fejgin was a Polish-born Jewish female physician. Among Fejgin’s numerous articles in the field of microbiology, her later work was almost entirely devoted to phage research.
Andrzej Grzybowski +4 more
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Do Anti-Phage Antibodies Persist after Phage Therapy? A Preliminary Report
Antibiotics, 2022 Phages are immunogenic and may evoke an immune response following their administration. Consequently, patients undergoing phage therapy (PT) produce phage-neutralizing serum antibodies.
Marzanna Łusiak-Szelachowska +5 more
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Viruses, 2022 The year 2020 marked 15 years of the Phage Therapy Unit in Poland, the inception of which took place just one year after Poland’s accession to the European Union (2004).
Maciej Żaczek +7 more
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Bacteriophage Therapy: Developments and Directions [PDF]
Antibiotics, 2020 In an era of proliferating multidrug resistant bacterial infections that are exhausting the capacity of existing chemical antibiotics and in which the development of new antibiotics is significantly rarer, Western medicine must seek additional therapeutic options that can be employed to treat these infections.
Mikeljon P. Nikolich, Andrey A. Filippov
openaire +3 more sources
Real-Time qPCR as a Method for Detection of Antibody-Neutralized Phage Particles
Frontiers in Microbiology, 2017 The most common method for phage quantitation is the plaque assay, which relies on phage ability to infect bacteria. However, non-infective phage particles may preserve other biological properties; specifically, they may enter interactions with the ...
Anna Kłopot +11 more
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Phage Prevalence in the Human Urinary Tract—Current Knowledge and Therapeutic Implications
Microorganisms, 2020 Recent metagenomic analyses imply an immense abundance of phages in the human body. Samples collected from different sites (lungs, skin, oral cavity, intestines, ascitic fluid, and urine) reveal a generally greater number of phage particles than that of ...
Maciej Żaczek +3 more
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Phage Interactions with the Nervous System in Health and Disease
Cells, 2023 The central nervous system manages all of our activities (e.g., direct thinking and decision-making processes). It receives information from the environment and responds to environmental stimuli.
Adam Jędrusiak +4 more
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