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In recent years, multidrug-resistant (MDR) strains of Klebsiella pneumoniae have spread globally, being responsible for the occurrence and severity of nosocomial infections.
Beata Weber-Dąbrowska +11 more
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Bacteriophage therapy: a regulatory perspective [PDF]
Despite the recognized problem of antibiotic multidrug resistance, very few antibacterial agents with new mechanisms of action are under development. Bacteriophage therapy could offer one alternative strategy to mitigate this challenge. Although widely used throughout the 20th century in Eastern Europe and the former Soviet Union, this potential ...
Eric, Pelfrene +4 more
openaire +2 more sources
Circulation of Fluorescently Labelled Phage in a Murine Model
Interactions between bacteriophages and mammals strongly affect possible applications of bacteriophages. This has created a need for tools that facilitate studies of phage circulation and deposition in tissues.
Zuzanna Kaźmierczak +4 more
doaj +1 more source
The Presence of Bacteriophages in the Human Body: Good, Bad or Neutral?
The presence of bacteriophages (phages) in the human body may impact bacterial microbiota and modulate immunity. The role of phages in human microbiome studies and diseases is poorly understood.
Marzanna Łusiak-Szelachowska +4 more
doaj +1 more source
Investigation Of Oriented Immobilization Of Bacteriophage For Fabrication Of Free Label Biosensor
One of the dangerous human pathogens is Escherichia coli (E. coli). It causes life-threatening difficulties such as bloody diarrhea and renal failure. The study and preparation of E.
Ali Mohammadi +5 more
core +1 more source
Silk route to the acceptance and re-implementation of bacteriophage therapy - Expert round table on acceptance and re-implementation of bacteriophage therapy [PDF]
This multidisciplinary expert panel opinion on bacteriophage therapy has been written in the context of a society that is confronted with an everincreasing number of antibiotic resistant bacteria.
Bretaudeau, Laurent +11 more
core +3 more sources
What Are the Potential Benefits of Using Bacteriophages in Periodontal Therapy?
Periodontitis, which may result in tooth loss, constitutes both a serious medical and social problem. This pathology, if not treated, can contribute to the development of, among others, pancreatic cancer, cardiovascular diseases or Alzheimer’s disease ...
Jan Kowalski +4 more
doaj +1 more source
Although phage discovery is an unquestionable merit of the English bacteriologist Frederick W. Twort and the Canadian–French microbiologist Félix d’Hérelle, who both discovered phages over 100 years ago, the Polish history of phage studies also dates ...
Maciej Żaczek +8 more
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When bacteriophages encounter macrophages during their journey through the human body
The increasing problem of antibiotic resistance is one of the most significant threats to global public health, contributing to higher mortality rates, prolonged hospitalizations, and rising healthcare costs.
Martyna Cieślik +5 more
doaj +1 more source
The Appearance of Antiphage Antibodies in Sera of Patients Treated with Phages
Background: Bacteriophages are neutralized by the sera of patients undergoing phage therapy (PT), particularly during local or concomitant local and oral phage administration in bone infections, soft tissue infections, or upper respiratory tract ...
Marzanna Łusiak-Szelachowska +4 more
doaj +1 more source

