Results 51 to 60 of about 2,435,226 (154)

Safety Studies of Pneumococcal Endolysins Cpl-1 and Pal

Viruses, 2018
Bacteriophage-derived endolysins have gained increasing attention as potent antimicrobial agents and numerous publications document the in vivo efficacy of these enzymes in various rodent models. However, little has been documented about their safety and
Marek Harhala, Daniel C. Nelson, Paulina Miernikiewicz, Ryan D. Heselpoth, Beata Brzezicka, Joanna Majewska, Sara B. Linden, Xiaoran Shang, Aleksander Szymczak, Dorota Lecion, Karolina Marek-Bukowiec, Marlena Kłak, Bartosz Wojciechowicz, Karolina Lahutta, Andrzej Konieczny, Krystyna Dąbrowska   +15 more
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Bacteriophage Therapy: Recent Developments and Applications of a Renaissance Weapon

The spreading antibiotic resistance of bacteria is one of the most important challenges of modern medicine, and a search for methods that could replace conventional treatments of bacterial infections is urgently needed.

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The role of regulated clinical trials in the development of bacteriophage therapeutics. [PDF]

, 2012
Antibiotic resistance is now recognized as a major, global threat to human health and the need for the development of novel antibacterial therapies has become urgent. Lytic bacteriophages (phages) targeting individual bacterial pathogens have therapeutic
McConville, ML, Burrowes, BH, Enright, Mark, Harper, DR, Parracho, HM   +4 more
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Phage Therapy: Beyond Antibacterial Action

Frontiers in Medicine, 2018
Until recently, phages were considered as mere “bacteria eaters” with potential for use in combating antimicrobial resistance. The real value of phage therapy assessed according to the standards of evidence-based medicine awaits confirmation by clinical ...
Andrzej Górski, Andrzej Górski, Andrzej Górski, Ewa Jończyk-Matysiak, Ryszard Międzybrodzki, Ryszard Międzybrodzki, Ryszard Międzybrodzki, Beata Weber-Dąbrowska, Beata Weber-Dąbrowska, Marzanna Łusiak-Szelachowska, Natalia Bagińska, Jan Borysowski, Małgorzata B. Łobocka, Małgorzata B. Łobocka, Alicja Węgrzyn, Grzegorz Węgrzyn   +15 more
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“Phage Transplantation in Allotransplantation”: Possible Treatment in Graft-Versus-Host Disease?

Frontiers in Immunology, 2018
Graft-versus-host disease, both acute and chronic (aGvHD, cGvHD) remains a major complication in patients undergoing hematopoietic cell transplantation (HCT) and a significant therapeutic challenge, as many patients do not respond adequately to presently
Andrzej Górski, Andrzej Górski, Andrzej Górski, Ewa Jończyk-Matysiak, Ryszard Międzybrodzki, Ryszard Międzybrodzki, Ryszard Międzybrodzki, Beata Weber-Dąbrowska, Beata Weber-Dąbrowska, Jan Borysowski   +9 more
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Protecting Newborns from Multidrug-Resistant Infections: The Emerging Role of Bacteriophages

Viruses
Newborns may suffer from dangerous bacterial infections caused by life-threatening multi-drug resistant pathogens. Thus, despite bactericidal capabilities of antibiotics, microorganisms are known to circumvent this therapy, and a new, more effective type
Olaf Bajrak, Andrzej Górski, Ewa Jończyk-Matysiak   +2 more
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Phage Therapy: What Have We Learned?

Viruses, 2018
In this article we explain how current events in the field of phage therapy may positively influence its future development. We discuss the shift in position of the authorities, academia, media, non-governmental organizations, regulatory agencies ...
Andrzej Górski, Ryszard Międzybrodzki, Małgorzata Łobocka, Aleksandra Głowacka-Rutkowska, Agnieszka Bednarek, Jan Borysowski, Ewa Jończyk-Matysiak, Marzanna Łusiak-Szelachowska, Beata Weber-Dąbrowska, Natalia Bagińska, Sławomir Letkiewicz, Krystyna Dąbrowska, Jacques Scheres   +12 more
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Phage Therapy in Prostatitis: Recent Prospects

Frontiers in Microbiology, 2018
Prostatitis has various etiology including bacterial infection and dysregulated immunity; some of its forms remain a serious therapeutic challenge. Inflammation occurs in all forms of this disorder and is proposed to predispose to the development of ...
Andrzej Górski, Andrzej Górski, Andrzej Górski, Ewa Jończyk-Matysiak, Marzanna Łusiak-Szelachowska, Ryszard Międzybrodzki, Ryszard Międzybrodzki, Ryszard Międzybrodzki, Beata Weber-Dąbrowska, Beata Weber-Dąbrowska, Jan Borysowski, Sławomir Letkiewicz, Sławomir Letkiewicz, Natalia Bagińska, Karen S. Sfanos, Karen S. Sfanos, Karen S. Sfanos   +16 more
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Bacteriophage-based therapy in cystic fibrosis-associated Pseudomonas aeruginosa infections: rationale and current status

, 2015
Sami Hraiech,1,2 Fabienne Brégeon,1,3 Jean-Marc Rolain1 1Institut Hospitalo-Universitaire Méditerranée Infection, URMITE CNRS IRD INSERM UMR 7278, 2Réanimation Médicale – Détresses Respiratoires et ...
Brégeon F, Rolain JM, Hraiech S
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Investigation Of Oriented Immobilization Of Bacteriophage For Fabrication Of Free Label Biosensor

, 2022
One of the dangerous human pathogens is Escherichia coli (E. coli). It causes life-threatening difficulties such as bloody diarrhea and renal failure. The study and preparation of E.
Ali Mohammadi, Khadijeh Eskandari, Shima Nayeri, Masumeh Goodarzi, Jamal Rashidiani, Farshad Eskandari   +5 more
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