Results 91 to 100 of about 140,627 (227)

Structural investigation of human U6 snRNA recognition by spliceosomal recycling factor SART3 RNA recognition motifs

The FEBS Journal, EarlyView.
Human SART3 has two RRM domains to engage with U6 snRNA for spliceosome recycling. This study reports solution structures of SART3 RRM domains and investigates the interaction between RRM and U6 snRNA. SART3 binds to the asymmetric bulge of U6 snRNA as a dimer via conserved positively charged surfaces.
Iktae Kim, Kyeong‐Mi Bang, So Young An, Changkon Park, Ji‐Yeon Shin, Youngim Kim, Hyun Kyu Song, Jeong‐Yong Suh, Nak‐Kyoon Kim   +8 more
wiley   +1 more source

IMMUNOLOGIC ASPECTS OF PHAGE THERAPY OF INFECTIONS RELATED TO MEDICAL CARE IN NEUROREANIMATION

Журнал микробиологии, эпидемиологии и иммунобиологии, 2017
Aim. Evaluate the effect of anti-phage humoral immune response on effectiveness of phage therapy of infections related to medical care (IRMC). Materials and methods. 42 patients on extended mechanical ventilation (MV) in neuroreanimation, 1 time in 2014,
S. S. Bochkareva, A. V. Aleshkin, O. N. Ershova, L. I. Novikova, S. S. Afanasiev, I. A. Kiseleva, E. R. Zulkarneev, E. O. Rubalsky, O. Yu. Borisova, A. V. Karaulov   +9 more
doaj   +1 more source

Correction to: Multireceptor phage cocktail against Salmonella enterica to circumvent phage resistance. [PDF]

Microlife
europepmc   +2 more sources

Binding of Bacillus subtilis dynamin‐like protein DynA to the bacterial membrane is essential for effective phage defense

The FEBS Journal, EarlyView.
The bacterial dynamin‐like protein DynA from Bacillus subtilis plays a key role in phage defense. It binds the plasma membrane through a unique paddle domain in its D1 subunit. This membrane association is essential for its protective function, likely preventing explosive membrane rupture following phage infection.
Samia Shafqat, Urska Repnik, Marc Bramkamp   +2 more
wiley   +1 more source

Characterization of Two Novel Bacteriophages Infecting Multidrug-Resistant (MDR) Acinetobacter baumannii and Evaluation of Their Therapeutic Efficacy in Vivo

Frontiers in Microbiology, 2018
Acinetobacter baumannii is emerging as a challenging nosocomial pathogen due to its rapid evolution of antibiotic resistance. We report characterization of two novel bacteriophages, PBAB08 and PBAB25, infecting clinically isolated, multidrug-resistant ...
Kyoungeun Cha, Kyoungeun Cha, Hynu K. Oh, Jae Y. Jang, Yunyeol Jo, Won K. Kim, Geon U. Ha, Kwan S. Ko, Heejoon Myung, Heejoon Myung   +9 more
doaj   +1 more source

Development and mouse model evaluation of a new phage cocktail intended as an alternative to antibiotics for treatment of Staphylococcus aureus-induced bovine mastitis.

Journal of Dairy Science
Bovine mastitis (BM) is a prevalent infectious disease in dairy herds worldwide, resulting in substantial economic losses. Staphylococcus aureus is a major cause of mastitis in animals, and its antibiotic resistance poses challenges for treatment ...
Mengting Guo, Yumin Zhang, Lifei Wu, Yangjing Xiong, Lu Xia, Yuqiang Cheng, Jingjiao Ma, Hengan Wang, Jianhe Sun, Zhaofei Wang, Yaxian Yan   +10 more
semanticscholar   +1 more source

From bacterial predators to partners: phages in agriculture

New Phytologist, EarlyView.
Summary Bacteriophages, viruses that infect bacteria, are critical players for shaping the taxonomic and functional composition of plant‐associated microbiomes. Yet, their roles in plant health remain overlooked, along with their implications for sustainable agriculture.
Zahra Salehimoghaddam, Alexander P. Hynes, Rebecca T. Doyle   +2 more
wiley   +1 more source

In Vitro Design and Evaluation of Phage Cocktails Against Aeromonas salmonicida [PDF]

Frontiers in Microbiology, 2018
As an alternative approach against multidrug-resistant bacterial infections, phages are now being increasingly investigated as effective therapeutic agents. Here, aiming to design an efficient phage cocktail against Aeromonas salmonicida infections, we isolated and characterized five lytic A.
Ling Chen, Shengjian Yuan, Quan Liu, Quan Liu, Guoqin Mai, Jinfang Yang, Deng Deng, Bingzhao Zhang, Chenli Liu, Yingfei Ma   +9 more
openaire   +3 more sources

The PtrC2H2.2‐6‐PtrCYP86A7/A8 Module Regulates Poplar Drought Tolerance Through Mediating Cutin and Wax Biosynthesis Pathways

Plant Biotechnology Journal, EarlyView.
ABSTRACT The plant cuticle, composed of cutin and wax, is crucial for reducing non‐stomatal water loss and enhancing drought tolerance. CYP86A genes are key regulators of cutin and wax biosynthesis, yet the mechanisms controlling their expression remain unclear.
Jiu‐Jiu Zhao, Shuang‐Lian Deng, Hao Li, Shu‐Ying Wei, Rui‐Quan Wang, Yuan Zhang, Xiang Xiang, Peng Yang, Jing Li, Ting Wang, Jinliang Huang, Liang‐Hua Chen, HanBo Yang, Xue‐Qin Wan, Fang He   +14 more
wiley   +1 more source

Designing phage cocktails to combat the emergence of bacteriophage-resistant mutants in multidrug-resistant Klebsiella pneumoniae

Microbiology Spectrum
Phage therapy, an emerging strategy in the fight against recalcitrant bacterial infections, encounters a significant hurdle posed by the development of phage-resistant bacterial strains. To address this concern, we suggest a novel phage cocktail.
Seongjun Yoo, Kang-Mu Lee, Nayoung Kim, Thao Nguyen Vu, Ricardo Abadie, Dongeun Yong   +5 more
doaj   +1 more source