Results 71 to 80 of about 17,973 (167)

Omics Insights Into the Effects of Highbush Blueberry and Cranberry Crop Agroecosystems on Honey Bee Health and Physiology

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Honey bees (Apis mellifera) are vital pollinators in fruit‐producing agroecosystems like highbush blueberry (HBB) and cranberry (CRA). However, their health is threatened by multiple interacting stressors, including pesticides, pathogens, and nutritional changes.
Huan Zhong   +25 more
wiley   +1 more source

In Vitro Design and Evaluation of Phage Cocktails Against Aeromonas salmonicida [PDF]

open access: yesFrontiers in Microbiology, 2018
As an alternative approach against multidrug-resistant bacterial infections, phages are now being increasingly investigated as effective therapeutic agents. Here, aiming to design an efficient phage cocktail against Aeromonas salmonicida infections, we isolated and characterized five lytic A.
Ling Chen   +9 more
openaire   +3 more sources

Characterization of Two Novel Bacteriophages Infecting Multidrug-Resistant (MDR) Acinetobacter baumannii and Evaluation of Their Therapeutic Efficacy in Vivo

open access: yesFrontiers in Microbiology, 2018
Acinetobacter baumannii is emerging as a challenging nosocomial pathogen due to its rapid evolution of antibiotic resistance. We report characterization of two novel bacteriophages, PBAB08 and PBAB25, infecting clinically isolated, multidrug-resistant ...
Kyoungeun Cha   +9 more
doaj   +1 more source

Phage Cocktail in Combination with Kasugamycin as a Potential Treatment for Fire Blight Caused by Erwinia amylovora

open access: yesAntibiotics, 2022
Recently, there has been an increasing number of blight disease reports associated with Erwinia amylovora and Erwinia pyrifoliae in South Korea. Current management protocols that have been conducted with antibiotics have faced resistance problems and the
Sang-Guen Kim   +12 more
doaj   +1 more source

Large‐Scale Structural Dynamics in the Tail Fiber Modulate the Infective Transition of the T7 Bacteriophage

open access: yesSmall, EarlyView.
During host recognition, the fibers of T7 bacteriophages transition from a capsid bound state to an extended conformation, which requires some level of fiber flexibility. By using high‐speed atomic force microscopy, we show that the fibers have an internal molecular hinge and a torsionally compliant coiled‐coil region.
Luca Elizabet Kosik   +16 more
wiley   +1 more source

IMMUNOLOGIC ASPECTS OF PHAGE THERAPY OF INFECTIONS RELATED TO MEDICAL CARE IN NEUROREANIMATION

open access: yesЖурнал микробиологии, эпидемиологии и иммунобиологии, 2017
Aim. Evaluate the effect of anti-phage humoral immune response on effectiveness of phage therapy of infections related to medical care (IRMC). Materials and methods. 42 patients on extended mechanical ventilation (MV) in neuroreanimation, 1 time in 2014,
S. S. Bochkareva   +9 more
doaj   +1 more source

Rapid and efficient quality control analysis of isolated mitochondria by interferometric light microscopy

open access: yesVIEW, EarlyView.
Mitochrial transplantation is a promising therapy to restore energy in damaged cells, but it lacks fast and reliable methods to assess mitochondrial quality before use. In this study, we used a label‐free imaging technique called interferometric light microscopy to rapidly measure the size and concentration of isolated mitochondria.
Sabah Mozafari   +5 more
wiley   +1 more source

Directed in Vitro Evolution of Therapeutic Bacteriophages: The Appelmans Protocol

open access: yesViruses, 2019
The ‘Appelmans protocol’ is used by Eastern European researchers to generate therapeutic phages with novel lytic host ranges. Phage cocktails are iteratively grown on a suite of mostly refractory bacterial isolates until the evolved cocktail ...
Ben H. Burrowes   +2 more
doaj   +1 more source

Biochemical and structural characterization of a tail‐spike protein with depolymerase activity identified in a marine podovirus

open access: yesActa Crystallographica Section D, EarlyView.
The marine tail‐spike protein Dpo31 degrades the exopolysaccharide of its host and has structural features similar to those of other members of this protein class, despite similarity not being detected at the sequence level.Marine phages are, through the infection of their bacterial hosts, key regulators of microbiome and carbon fluxes in the ocean ...
Serena Sirigu   +7 more
wiley   +1 more source

Designing phage cocktails to combat the emergence of bacteriophage-resistant mutants in multidrug-resistant Klebsiella pneumoniae

open access: yesMicrobiology Spectrum
Phage therapy, an emerging strategy in the fight against recalcitrant bacterial infections, encounters a significant hurdle posed by the development of phage-resistant bacterial strains. To address this concern, we suggest a novel phage cocktail.
Seongjun Yoo   +5 more
doaj   +1 more source

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