Results 61 to 70 of about 102,405 (155)

Development and Evaluation of Bacteriophage Cocktail to Eradicate Biofilms Formed by an Extensively Drug-Resistant (XDR) Pseudomonas aeruginosa

Viruses, 2023
Extensive and multiple drug resistance in P. aeruginosa combined with the formation of biofilms is responsible for its high persistence in nosocomial infections.
Medhavi Vashisth, Anu Bala Jaglan, Shikha Yashveer, Priya Sharma, Priyanka Bardajatya, Nitin Virmani, Bidhan Chand Bera, Rajesh Kumar Vaid, Taruna Anand   +8 more
doaj   +1 more source

Programmable Assembly of Higher‐Order DNA Nanostructures from Microbial ssDNA Staple Libraries

Small, EarlyView.
A phage‐free, microbial platform produces programmable circular ssDNA libraries that are enzymatically converted into DNA origami staple pools. Rolling‐circle replication generates sequence‐complex ssDNA with >99% fidelity, enabling assembly of DNA tiles and tubules and supporting nanostructure formation even in crude cellular lysates.
Ming Hung Yen, Mallikarjuna Reddy Kesama, Yancheng Du, Jong Hyun Choi, Kevin V. Solomon   +4 more
wiley   +1 more source

Delayed treatment with phage cocktail.

, 2013
Mice were inoculated intraperitoneally with K7 at the dose of 2.5×108 cfu. Cocktail phages at the dose of 3.0×104 pfu or a buffer were administered into the peritoneal cavities of mice at the indicated time intervals after challenging with K7.
Jun Song (19318), Liancheng Lei (111464), Yu Gao (69071), Rong Lu (53910), Xiaohe Liu (330794), Xin Feng (111466), Yue Li (102191), Jingmin Gu (330793), Honglei Zhao (330799), Changjiang Sun (111462), Wenyu Han (330797), Yongjun Yang (330798)   +11 more
core   +1 more source

Enhanced suppression of <i>Stenotrophomonas maltophilia</i> by a three-phage cocktail: genomic insights and kinetic profiling. [PDF]

Antimicrob Agents Chemother
Stenotrophomonas maltophilia is an understudied, gram-negative, aerobic bacterium that is widespread in the environment and increasingly a cause of opportunistic infections. Treating S.
Monsibais AN, Tea O, Ghatbale P, Dunham SJB, Zünd M, Phan J, Lam K, Paulson M, Tran N, Suder DS, Blanc AN, Samillano C, Suh J, Atif H, Vien E, Nguyen R, Vo A, Gonen S, Pride D, Whiteson K.   +19 more
europepmc   +2 more sources

Oral microbiome and homeostatic regulation of periodontal health: From dysbiosis to precision intervention

VIEW, EarlyView.
Periodontal homeostasis is maintained by coordinated interactions between the oral microbiome and host. Dysbiosis disrupts this ecological balance and contributes to periodontal disease, whereas multi‐omics, artificial intelligence, and microbiome‐based interventions provide emerging opportunities for precision diagnosis, ecological restoration, and ...
Xu Liu, Lei Meng, Wenzhu Song, Peiyu Wang, Bin Liu, Shihui Liu, Qi He, Bing Sun, Wanheng Li, Zhiwei Guan, Rui Dong, Qiang Feng   +11 more
wiley   +1 more source

IgE‐Binding Bacterial Components Not Yet Documented in the Allergen Databases and Their Allergenic Mechanisms: An EAACI Position Paper

Allergy, EarlyView.
ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe, Marua Abu Risha, Ioana Agache, Claus Bachert, Barbara Bröker, Riccardo Castagnoli, Gabriele Gadermaier, Richard E. Goodman, Amir Guemari, Christiane Hilger, Alain Jacquet, Sabine Kespohl, Ludger Klimek, Annette Kuehn, Jonas Lidholm, Vera Mahler, Markus Ollert, Thomas A. Platts‐Mills, Monika Raulf, Peter Schmid‐Grendelmeier, Frieder Schmiedeke, Marianne van Hage, Joana Vitte, Josefina Zakzuk, Anna Pomés   +24 more
wiley   +1 more source

Self-assembly of Escherichia coli phage shock protein A

, 2014
The Phage shock protein (Psp) response is an extracytoplasmic stress response. The central component of this system is PspA, a protein that mediates the physiological response to membrane stress.
Male, Abigail, Tavassoli, Ali
core   +1 more source

Identification of hepatitis a virus mimotopes by phage display, antigenicity and immunogenicity [PDF]

, 2007
A phage-displayed peptide approach was used to identify ligands mimicking antigenic determinants of hepatitis A virus (HAV) for the first time. Bacteriophages displaying HAV mimotopes were isolated from a phage-display peptide library by affinity ...
Camacho, F., Perez, E.M., Amin, N., Aguilar, A., David I. Stott, Talavera, A., Arturo Talavera, Raiza Martinez, Frank Camacho, Nevis Amin, Ela M. Perez, Larralde, O.G., Alicia Aguilar, Martinez, R., Osmany G. Larralde, Stott, D.I.   +15 more
core   +1 more source

Transgenic selection and underlying mechanisms in apicomplexan parasites

The FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju, Rakhee Lohia, Nishith Gupta   +2 more
wiley   +1 more source

Directed in Vitro Evolution of Therapeutic Bacteriophages: The Appelmans Protocol

Viruses, 2019
The ‘Appelmans protocol’ is used by Eastern European researchers to generate therapeutic phages with novel lytic host ranges. Phage cocktails are iteratively grown on a suite of mostly refractory bacterial isolates until the evolved cocktail ...
Ben H. Burrowes, Ian J. Molineux, Joe A. Fralick   +2 more
doaj   +1 more source