Results 101 to 110 of about 140,627 (227)

Three New Escherichia coli Phages from the Human Gut Show Promising Potential for Phage Therapy. [PDF]

PLoS ONE, 2016
With the emergence of multi-drug resistant bacteria the use of bacteriophages (phages) is gaining renewed interest as promising anti-microbial agents. The aim of this study was to isolate and characterize phages from human fecal samples.
Marion Dalmasso, Ronan Strain, Horst Neve, Charles M A P Franz, Fabien J Cousin, R Paul Ross, Colin Hill   +6 more
doaj   +1 more source

Lytic Activity of Various Phage Cocktails on Multidrug-Resistant Bacteria

Clinical and Investigative Medicine, 2016
Purpose A bacteriophage is a virus that infects and replicates within a bacterium following the injection of phage genome into the bacterial cytoplasm. They are seen as a possible therapy for multi-drug-resistant strains of many bacteria. The aim of this study is to evaluate the lytic activity of the Pyo, Intesti and Fersisi bacteriophage cocktails on ...
I, Ozkan, E, Akturk, N, Yeshenkulov, S, Atmaca, N, Rahmanov, H I, Atabay   +5 more
openaire   +3 more sources

Phage Display Derived Antibodies Against Antimicrobial Peptide FsPDF2 Reveal Stress Response in European Beech

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant defensins (PDFs) are cysteine‐rich antimicrobial peptides (AMPs) that are important components of plant immunity. They occur constitutively in various plant tissues but are also upregulated upon stress. Therefore, these molecules are of great interest as markers for the diagnosis of early forest stress response in plants at the molecular
Philip Alexander Heine, Tetyana Nosenko, Sarah Kistner, Kevin Dennis Oliphant, Manuel Hanke‐Uhe, Afsheen Shahid, Bin Hu, Martin Kucklick, Nina Lehmler, Marlies Becker, Nicole Goerke, Janin Korn, Tanja Linke, Doris Meier, Asta Perl, Saskia Polten, Valeska Priess, Dorina Schäckermann, Maren Schubert, Jörg Schumacher, Jana Barbro Winkler, Susanne Engelmann, Heinz Rennenberg, Jörg‐Peter Schnitzler, Stefan Dübel, Michael Hust, Robert Hänsch, David Kaufholdt   +27 more
wiley   +1 more source

Plastid Engineering for Photosynthesis‐Driven Synthesis of Hyaluronic Acid in Tobacco

Plant Biotechnology Journal, EarlyView.
ABSTRACT Hyaluronic acid (HA) is a glycosaminoglycan composed of alternating units of N‐acetylglucosamine and glucuronic acid. High moisture retention, viscoelasticity and biocompatibility are unique features that make HA polymers attractive compounds for medical applications and aesthetic purposes.
Amanda Lopes, Omar Sandoval‐Ibáñez, Stéphanie Arrivault, David Rolo, F. Vanessa Loiacono, Alexander Erban, Daniel Karcher, Stephan Obst, Stephanie Ruf, Joachim Kopka, Ralph Bock   +10 more
wiley   +1 more source

Multiple factorial analysis of growth performance, gut population, lipid profiles, immune responses, intestinal histomorphology, and relative organ weights of Cobb 500 broilers fed a diet supplemented with phage cocktail and probiotics

Italian Journal of Animal Science
Previous studies on probiotics in chickens have shown varying efficacy, and the use of phage as a supplement for improving chicken performance and health has gained interest.
Mohd Asrore Mohd Shaufi, C. C. Sieo, Chun Wie Chong, Geok Hun Tan, Abdul Rahman Omar, Y. Ho   +5 more
semanticscholar   +1 more source

Core Lipopolysaccharide-Specific Phage SSU5 as an Auxiliary Component of a Phage Cocktail for Salmonella Biocontrol [PDF]

Applied and Environmental Microbiology, 2014
ABSTRACT Salmonella spp. are among the major food-borne pathogens that cause mild diarrhea to severe bacteremia. The use of bacteriophages to control various food-borne pathogens, including Salmonella , has emerged as a promising alternative to traditional chemotherapy. We isolated the
Minsik, Kim, Sujin, Kim, Bookyung, Park, Sangryeol, Ryu   +3 more
openaire   +2 more sources

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Antibacterial effect of phage cocktails and phage-antibiotic synergy against pathogenic Klebsiella pneumoniae

mSystems
ABSTRACT The global rise of antibiotic resistance has renewed interest in phage therapy, as an alternative to antibiotics to eliminate multidrug-resistant (MDR) bacterial pathogens. However, optimizing the broad-spectrum efficacy of phage therapy remains a challenge.
Mengshi zhao, Hongru Li, Dehao Gan, Mengzhu Wang, Hui Deng, Qiu E. Yang   +5 more
openaire   +3 more sources

Computational Basis for On-Demand Production of Diversified Therapeutic Phage Cocktails

mSystems, 2020
The antibiotic resistance crisis has led to renewed interest in phage therapy as an alternative means of treating infection. However, conventional methods for isolating pathogen-specific phage are slow, labor-intensive, and frequently unsuccessful. We have demonstrated that computationally identified prophages carried by near-neighbor bacteria can ...
Catherine M. Mageeney, Anupama Sinha, Richard A. Mosesso, Douglas L. Medlin, Britney Y. Lau, Alecia B. Rokes, Todd W. Lane, Steven S. Branda, Kelly P. Williams   +8 more
openaire   +5 more sources

Bacteriophage and Fusidic Acid Have Synergistic Effect Against Meticillin‐Resistant Staphylococcus pseudintermedius in Ex Vivo Canine Dermis Model

Veterinary Dermatology, EarlyView.
Background: Antimicrobial stewardship has become vital given the progressive emergence of multidrug‐resistant bacteria, and novel approaches to the treatment of bacterial infections are needed. Recently, reported synergistic effects of antibacterial drugs and bacteriophage therapy have revealed promising applications for the management of meticillin ...
Sarah Ehling, Elisa Peh, Hilke Oltmanns, Jessica Meissner, Sophie Kittler, Christina Puff, Jutta Verspohl, Mathias Müsken, Madeleine Plötz, Andrea Vanessa Volk   +9 more
wiley   +1 more source