A method for generation phage cocktail with great therapeutic potential. [PDF]
PLoS ONE, 2012 BACKGROUND: Bacteriophage could be an alternative to conventional antibiotic therapy against multidrug-resistant bacteria. However, the emergence of resistant variants after phage treatment limited its therapeutic application.
Jingmin Gu +11 more
doaj +4 more sources
Rapid formulation of a genetically diverse phage cocktail targeting uropathogenic Escherichia coli infections using the UTI89 model. [PDF]
Sci RepUrinary tract infections are commonly caused by uropathogenic Escherichia coli (UPEC). Due to the emergence of multidrug-resistant UPEC, rendering antibiotic treatment ineffective, phage combination-based therapy has been proposed as a potential ...
Kongsomboonchoke P +6 more
europepmc +2 more sources
Successful Treatment of a Patient With Chronic Bronchiectasis Using an Induced Native Phage Cocktail: A Case Report. [PDF]
CureusBronchiectasis is a well-recognized chronic respiratory disease characterized by a productive cough and multi-microbial activation syndrome (MMAS) of various respiratory infections due to what can be the permanent dilatation of the bronchi ...
Jernigan DA, Hentish RD.
europepmc +2 more sources
Enhanced suppression of <i>Stenotrophomonas maltophilia</i> by a three-phage cocktail: genomic insights and kinetic profiling. [PDF]
Antimicrob Agents ChemotherStenotrophomonas maltophilia is an understudied, gram-negative, aerobic bacterium that is widespread in the environment and increasingly a cause of opportunistic infections. Treating S.
Monsibais AN +19 more
europepmc +2 more sources
Impact of a single phage and a phage cocktail application in broilers on reduction of Campylobacter jejuni and development of resistance. [PDF]
PLoS ONE, 2013 Campylobacteriosis is currently the most frequent foodborne zoonosis in many countries. One main source is poultry. The aim of this study was to enhance the knowledge about the potential of bacteriophages in reducing colonization of broilers with ...
Samuel Fischer +3 more
doaj +3 more sources
Microbiology Spectrum, 2022 O157:H7 is the most important Shiga toxin-producing Escherichia coli (STEC) serotype in relation to public health. Given that antibiotics may contribute to the exacerbation of STEC-related disease and an increased frequency of antibiotic-resistant ...
Yuxin Wang +8 more
doaj +2 more sources
Identification and impact on <i>Pseudomonas aeruginosa</i> virulence of mutations conferring resistance to a phage cocktail for phage therapy. [PDF]
Microbiol Spectr, 2023 Phage therapy represents a promising strategy for curing bacterial infections refractory to antibiotics. However, the success rate of phage therapy may be lowered by the emergence of bacterial resistance to the phages used for therapy.
Forti F +5 more
europepmc +2 more sources
Effects of Phage Cocktail, Probiotics, and Their Combination on Growth Performance and Gut Microbiota of Broiler Chickens. [PDF]
Animals (Basel), 2023 Simple Summary The emergence of antibiotic-resistant bacteria and the growing demand for poultry products have led to an interest in finding alternatives to antibiotic growth promoters (AGPs) used in poultry farming.
Shaufi MAM +6 more
europepmc +2 more sources
Control of Salmonella in Chicken Meat by a Phage Cocktail in Combination with Propionic Acid and Modified Atmosphere Packaging [PDF]
Foods, 2023 Salmonella contamination in poultry meat is an important food safety issue as this pathogen can lead to serious illness and economic losses worldwide.
Wattana Pelyuntha, K. Vongkamjan
europepmc +2 more sources
Comparative analysis of effectiveness for phage cocktail development against multiple Salmonella serovars and its biofilm control activity. [PDF]
Sci Rep, 2023 Foodborne diseases are a major challenge in the global food industry, especially those caused by multidrug-resistant (MDR) bacteria. Bacteria capable of biofilm formation, in addition to MDR strains, reduce the treatment efficacy, posing a significant ...
Ribeiro JM +7 more
europepmc +2 more sources