Results 31 to 40 of about 140,627 (227)

Phage cocktail amikacin combination as a potential therapy for bacteremia associated with carbapenemase producing colistin resistant Klebsiella pneumoniae. [PDF]

Sci Rep
The increasing occurrence of hospital-associated infections, particularly bacteremia, caused by extensively drug-resistant (XDR) carbapenemase-producing colistin-resistant Klebsiella pneumoniae highlights a critical requirement to discover new ...
Shein AMS, Wannigama DL, Hurst C, Monk PN, Amarasiri M, Wongsurawat T, Jenjaroenpun P, Phattharapornjaroen P, Ditcham WGF, Ounjai P, Saethang T, Chantaravisoot N, Badavath VN, Luk-In S, Nilgate S, Rirerm U, Srisakul S, Kueakulpattana N, Laowansiri M, Rad SMAH, Wacharapluesadee S, Rodpan A, Ngamwongsatit N, Thammahong A, Ishikawa H, Storer RJ, Leelahavanichkul A, Ragupathi NKD, Classen AY, Kanjanabuch T, Pletzer D, Miyanaga K, Cui L, Hamamoto H, Higgins PG, Kicic A, Chatsuwan T, Hongsing P, Abe S.   +38 more
europepmc   +2 more sources

Oral Administration of a Phage Cocktail to Reduce Salmonella Colonization in Broiler Gastrointestinal Tract—A Pilot Study [PDF]

Animals, 2022
Salmonella contamination in poultry meat products can lead to serious foodborne illness and economic loss from product recalls. It is crucial to control Salmonella contamination in poultry from farm to fork.
Wattana Pelyuntha, Ananya Yafa, Ruttayaporn Ngasaman, Mingkwan Yingkajorn, Kridda Chukiatsiri, Nidanut Champoochana, Kitiya Vongkamjan   +6 more
doaj   +2 more sources

Phage Cocktail in Combination with Kasugamycin as a Potential Treatment for Fire Blight Caused by Erwinia amylovora [PDF]

Antibiotics, 2022
Recently, there has been an increasing number of blight disease reports associated with Erwinia amylovora and Erwinia pyrifoliae in South Korea. Current management protocols that have been conducted with antibiotics have faced resistance problems and the
Sang-Guen Kim, Sung-Bin Lee, Su-Jin Jo, Kevin Cho, Jung-Kum Park, Jun Kwon, Sib Sankar Giri, Sang-Wha Kim, Jeong-Woo Kang, Won-Joon Jung, Young-Min Lee, Eunjung Roh, Se-Chang Park   +12 more
doaj   +2 more sources

The Efficacy of Inhaled Phage Cocktail to Prevent Ventilator-Associated Pneumonia in Children: A Double-Blind Clinical Trial. [PDF]

Biomedicines
Navaeifar MR, Rahimzadeh G, Rezai R, Ranjbar H, Asare-Addo K, Nokhodchi A, Rezai MS.   +6 more
europepmc   +3 more sources

Evaluation of phage cocktail efficacy for controlling infections caused by pathogenic Escherichia coli in in vivo experiments [PDF]

BIO Web of Conferences
Colibacillosis is a common veterinary infection that causes huge economic losses to the livestock and poultry industry. Uncontrolled use of antibiotics has led to the emergence and spread of multidrug resistant bacteria and has reduced the effectiveness ...
Madina Alexyuk, Pavel Alexyuk, Yergali Moldakhanov, Kuralai Akanova, Andrey Bogoyavlenskiy   +4 more
openalex   +2 more sources

Development of a broad-host-range phage cocktail for biocontrol [PDF]

Bioengineered Bugs, 2011
The aims of this study were to investigate the incidence of different resistance mechanisms to phage K in a bank of Irish Staph aureus hospital strains; and to develop a broad host-range phage cocktail with enhanced lytic activity against those strains which were previously phage resistant.
David Kelly, Olivia McAuliffe, Jim O’Mahony, Aidan Coffey   +3 more
openalex   +3 more sources

Phage Cocktails can Prevent the Evolution of Phage-Resistant Enterococcus [PDF]

, 2021
ABSTRACTAntibiotic resistantEnterococcusinfections are a major health crisis that requires the development of alternative therapies. Phage therapy could be an alternative to antibiotics and has shown promise inin vitroand in early clinical studies. Phage therapy is often deployed as a cocktail of phages, but there is little understanding of how to most
Stephen Wandro, Pooja Ghatbale, Hedieh Attai, Clark Hendrickson, Cyril Samillano, Joy Suh, David T. Pride, Katrine Whiteson   +7 more
openalex   +2 more sources

Phage Cocktails Constrain the Growth of Enterococcus [PDF]

mSystems, 2022
Due to the rise in antibiotic resistance, Enterococcus infections are a major health crisis that requires the development of alternative therapies. Phage therapy offers an alternative to antibiotics and has shown promise in both in vitro and early clinical studies.
Stephen Wandro, Pooja Ghatbale, Hedieh Attai, Clark Hendrickson, Cyril Samillano, Joy Suh, Sage J. B. Dunham, David T. Pride, Katrine Whiteson   +8 more
openaire   +4 more sources

Systematic analysis of putative phage-phage interactions on minimum-sized phage cocktails [PDF]

Scientific Reports, 2022
AbstractThe application of bacteriophages as antibacterial agents has many benefits in the “post-antibiotic age”. To increase the number of successfully targeted bacterial strains, phage cocktails, instead of a single phage, are commonly formulated. Nevertheless, there is currently no consensus pipeline for phage cocktail development.
Molina, Felipe, Menor-Flores, Manuel, Fernández Llamas, Lucía, Vega-Rodríguez, Miguel Ángel, García Suárez, María Pilar   +4 more
openaire   +4 more sources

Fitness Trade-Offs in Phage Cocktail-Resistant Salmonella enterica Serovar Enteritidis Results in Increased Antibiotic Susceptibility and Reduced Virulence

Microbiology Spectrum, 2022
The rapid emergence of phage-resistant bacterial mutants is a major challenge for phage therapy. Phage cocktails have been considered one approach to mitigate this issue.
Dongyang Gao, Hongyue Ji, Linkang Wang, Xinxin Li, Dayue Hu, Junna Zhao, Shuang Wang, Pan Tao, Xiangmin Li, Ping Qian   +9 more
doaj   +1 more source