Results 41 to 50 of about 171,183 (250)

Development of a Bacteriophage Cocktail to Constrain the Emergence of Phage-Resistant Pseudomonas aeruginosa

Frontiers in Microbiology, 2020
With the emergence of multidrug-resistant and extensively drug-resistant bacterial pathogens, phage therapy and other alternative or additional therapeutic modalities are receiving resurgent attention.
Yuhui Yang, Wei Shen, Qiu Zhong, Qian Chen, Xuesong He, Jonathon L. Baker, Kun Xiong, Xiaoling Jin, Jing Wang, Fuquan Hu, Shuai Le   +10 more
doaj   +1 more source

Inhibition of Antimicrobial-Resistant Escherichia coli Using a Broad Host Range Phage Cocktail Targeting Various Bacterial Phylogenetic Groups

Frontiers in Microbiology, 2021
Antimicrobial-resistant (AMR) commensal Escherichia coli is a major reservoir that disseminates antimicrobial resistance to humans through the consumption of contaminated foods, such as retail poultry products. This study aimed to control AMR E.
Jinshil Kim, Jinshil Kim, Haejoon Park, Haejoon Park, Sangryeol Ryu, Sangryeol Ryu, Byeonghwa Jeon   +6 more
doaj   +1 more source

Impact of a single phage and a phage cocktail application in broilers on reduction of Campylobacter jejuni and development of resistance. [PDF]

PLoS ONE, 2013
Campylobacteriosis is currently the most frequent foodborne zoonosis in many countries. One main source is poultry. The aim of this study was to enhance the knowledge about the potential of bacteriophages in reducing colonization of broilers with ...
Samuel Fischer, Sophie Kittler, Günter Klein, Gerhard Glünder   +3 more
doaj   +1 more source

A Method to Determine the Efficacy of a Commercial Phage Preparation against Uropathogens in Urine and Artificial Urine Determined by Isothermal Microcalorimetry

Microorganisms, 2022
Background: Urinary tract infections are commonly encountered and often treated with antibiotics. However, the inappropriate use of the latter has led to the appearance of resistant strains.
Aurelia Pahnita Sigg, Max Mariotti, Anabel E. Grütter, Tecla Lafranca, Lorenz Leitner, Gernot Bonkat, Olivier Braissant   +6 more
doaj   +1 more source

Characterization of 29 newly isolated bacteriophages as a potential therapeutic agent against IMP-6-producing Klebsiella pneumoniae from clinical specimens

Microbiology Spectrum, 2023
Carbapenemase-producing Enterobacteriaceae (CPE) are one of the most detrimental species of antibiotic-resistant bacteria globally. Phage therapy has emerged as an effective strategy for the treatment of CPE infections.
Kohei Kondo, Satoshi Nakano, Junzo Hisatsune, Yo Sugawara, Michiyo Kataoka, Shizuo Kayama, Motoyuki Sugai, Mitsuoki Kawano   +7 more
doaj   +1 more source

Isolation, characterisation and experimental evolution of phage that infect the horse chestnut tree pathogen, Pseudomonas syringae pv. aesculi [PDF]

, 2020
Bleeding canker of horse chestnut trees is a bacterial disease, caused by the bacterium Pseudomonas syringae pv. aesculi, estimated to be present in ~ 50% of UK horse chestnut trees.
Jackson, Robert W., James, Sarah L., Neuman, Benjamin W., Percival, Glynn, Rabiey, Mojgan   +4 more
core   +3 more sources

Phage Therapy vs. the Use of Antibiotics in the Treatment of Salmonella-Infected Chickens: Comparison of Effects on Hematological Parameters and Selected Biochemical Markers

Antibiotics, 2022
Previous studies indicated that the use of a phage cocktail, composed of bacteriophages vB_SenM-2 and vB_Sen-TO17, is effective in killing cells of Salmonella enterica serovars Typhimurium and Enteritidis in vitro and in the Galleria mellonella animal ...
Łukasz Grabowski, Grzegorz Węgrzyn, Alicja Węgrzyn, Magdalena Podlacha   +3 more
doaj   +1 more source

Phage Cocktails and the Future of Phage Therapy

Future Microbiology, 2013
Viruses of bacteria, known as bacteriophages or phages, were discovered nearly 100 years ago. Their potential as antibacterial agents was appreciated almost immediately, with the first 'phage therapy' trials predating Fleming's discovery of penicillin by approximately a decade.
Benjamin K, Chan, Stephen T, Abedon, Catherine, Loc-Carrillo   +2 more
openaire   +2 more sources

Phage Cocktails can Prevent the Evolution of Phage-ResistantEnterococcus [PDF]

, 2021
ABSTRACTAntibiotic resistantEnterococcusinfections are a major health crisis that requires the development of alternative therapies. Phage therapy could be an alternative to antibiotics and has shown promise inin vitroand in early clinical studies. Phage therapy is often deployed as a cocktail of phages, but there is little understanding of how to most
Stephen Wandro, Pooja Ghatbale, Hedieh Attai, Clark Hendrickson, Cyril Samillano, Joy Suh, David T. Pride, Katrine Whiteson   +7 more
openaire   +1 more source

Investigating bacteriophages targeting the opportunistic pathogen Acinetobacter baumannii [PDF]

, 2020
The multi-drug resistance of the opportunistic pathogen Acinetobacter baumannii is of growing concern, with many clinical isolates proving to be resistant to last resort as well as front line antibiotic treatments.
Christie, Gabrielle S., Dowson, Christopher G., Leungtongkam, Udomluk, Millard, Andrew D., Moat, John, Sagona, Antonia P., Sitthisak, Sutthirat, Smith, Sophie, Styles, Kathryn, Thummeepak, Rapee, Wellington, Elizabeth M. H.   +10 more
core   +1 more source