Results 91 to 100 of about 1,167,436 (302)

Isolation and genomic analysis of phage BUCT551 against drug-resistant Aeromonas hydrophila

Frontiers in Veterinary Science
Aeromonas hydrophila (A. hydrophila) is a common pathogen in aquaculture that also causes opportunistic infections and sporadic food- and water-borne illness in humans.
Pengjun Han, Pengjun Han, Hongbo Qin, Chenxi Hao, Zhiping Du, Yang Yang, Yang Yang   +6 more
doaj   +1 more source

Engineered CAR‐NKT Extracellular Vesicles Suppress Tumor Progression and Enhance Antitumor Immunity

Advanced Science, EarlyView.
TM4SF1‐nanobody engineered CAR‐natural killer T–derived extracellular vesicles (CARTM4SF1‐EVs) provide a cell‐free alternative to CAR‐NKT therapy, achieving potent, targeted antitumor activity with reduced toxicity. CARTM4SF1‐EVs induce immunogenic cell death, remodel the tumor microenvironment, and enhance CD8⁺ T‐cell antitumor immunity.
Xiaopei Hao, Chengming Qu, Yanzhao Zhou, Xiaoqian Wang, Xiangjun Qian, Xun Chen, Feng Han, Xiaokai Zhang, Yiyi Ji, Han Li, ChengWei Ju, Peng Xia, Weiwei Tang, Hao Zhuang, Jinxue Zhou   +14 more
wiley   +1 more source

Synthesis of Headful Packaging Phages Through Yeast Transformation-Associated Recombination

Viruses
De novo synthesis of phage genomes enables flexible genome modification and simplification. This study explores the synthetic genome assembly of Pseudomonas phage vB_PaeS_SCUT-S4 (S4), a 42,932 bp headful packaging phage, which encapsidates a terminally ...
Cheng Lu, Lan He, Yangyijun Guo, Tingting Wang, Yanrui Ye, Zhanglin Lin   +5 more
doaj   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Isolation and Genome Characterization of the Virulent Staphylococcus aureus Bacteriophage SA97

Viruses, 2015
A novel bacteriophage that infects S. aureus, SA97, was isolated and characterized. The phage SA97 belongs to the Siphoviridae family, and the cell wall teichoic acid (WTA) was found to be a host receptor of the phage SA97.
Yoonjee Chang, Hakdong Shin, Ju-Hoon Lee, Chul Jong Park, Soon-Young Paik, Sangryeol Ryu   +5 more
doaj   +1 more source

Complete Genome Sequences of Four Novel Escherichia coli Bacteriophages Belonging to New Phage Groups

Genome Announcements, 2015
Here, we describe the sequencing and genome annotations of a set of four Escherichia coli bacteriophages (phages) belonging to newly discovered groups previously consisting of only a single phage and thus expand our knowledge of these phage groups.
A. B. Carstens, W. Kot, L. Hansen
semanticscholar   +1 more source

Harnessing Large Language Models to Advance Microbiome Research: From Sequence Analysis to Clinical Applications

Advanced Intelligent Discovery, EarlyView.
Large language models are transforming microbiome research by enabling advanced sequence profiling, functional prediction, and association mining across complex datasets. They automate microbial classification and disease‐state recognition, improving cross‐study integration and clinical diagnostics.
Jieqi Xing, He Wang, Yangyang Sun, Xiaoquan Su, Shunyao Wu   +4 more
wiley   +1 more source

Characterization of a bacteriophage with broad host range against strains of Pseudomonas aeruginosa isolated from domestic animals

BMC Microbiology, 2019
Background Pseudomonas aeruginosa is an opportunistic pathogen and one of the leading causes of nosocomial infections. Moreover, the species can cause severe infections in cystic fibrosis patients, in burnt victims and cause disease in domestic animals ...
Anna Cristhina Carmine de Melo, Amanda da Mata Gomes, Fernando L. Melo, Daniel M. P. Ardisson-Araújo, Agueda Palmira Castagna de Vargas, Valessa Lunkes Ely, Elliot W. Kitajima, Bergmann M. Ribeiro, José Luiz Caldas Wolff   +8 more
doaj   +1 more source

Pseudomonas -Tailed Lytic Phages: Genome Mechanical Analysis And Putative Correlation With Virion Morphogenesis Yield

, 2022
Victor M. Balcão, Aakash Basu, Basilio Cieza, F. Rossi, Carla Pereira, Marta M. D. C. Vila, João Carlos Setúbal, Taekjip Ha, Aline Maria da Silva   +8 more
openalex   +1 more source

PhageTerm: a tool for fast and accurate determination of phage termini and packaging mechanism using next-generation sequencing data

Scientific Reports, 2017
The worrying rise of antibiotic resistance in pathogenic bacteria is leading to a renewed interest in bacteriophages as a treatment option. Novel sequencing technologies enable description of an increasing number of phage genomes, a critical piece of ...
Julian R. Garneau, F. Depardieu, L. Fortier, David Bikard, M. Monot   +4 more
semanticscholar   +1 more source