Abstract Background Phosphorylated signal transducer and activator of transcription 3 (p‐STAT3) has emerged as a critical modulator of hepatocellular carcinoma (HCC) progression. However, its role in three‐dimensional (3D) chromatin conformation and the expression of genes linked to HCC aggressiveness remains largely unexplored.
Sunyoung Jang+9 more
wiley +1 more source
PhamClust: a phage genome clustering tool using proteomic equivalence. [PDF]
Gauthier CH, Hatfull GF.
europepmc +1 more source
Role of the host cell in bacteriophage T4 development. II. Characterization of host mutants that have pleiotropic effects on T4 growth [PDF]
Mutant host-defective Escherichi coli that fail to propagate bacteriophage T4 and have a pleiotropic effect on T4 development have been isolated and characterized.
Lielausis, Ilga+3 more
core
Differential amplification of specific areas of phage T4 genome as revealed by hybridization to cloned genetic segments. [PDF]
Andrzej W. Kozinski+4 more
openalex +1 more source
Hijacking the Electron Train: Menaquinone‐Binding Antimicrobial Peptides
Menaquinone is an emerging target for antimicrobial peptides. Could it be the new Achilles’ Heel of bacteria? The rise of antibiotic resistance threatens to undermine modern medicine, making the development of new antibiotics and novel targets an urgent priority.
Eilidh J. Matheson, Stephen A. Cochrane
wiley +1 more source
The analysis of the function, diversity, and evolution of the Bacillus phage genome. [PDF]
Zhang Y+6 more
europepmc +1 more source
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal+14 more
wiley +1 more source
Divergent endophytic viromes and phage genome repertoires among banana (Musa) species. [PDF]
Aghdam SA, Lahowetz RM, Brown AMV.
europepmc +1 more source
Improved single-swab sample preparation for recovering bacterial and phage DNA from human skin and wound microbiomes. [PDF]
BackgroundCharacterization of the skin and wound microbiome is of high biomedical interest, but is hampered by the low biomass of typical samples. While sample preparation from other microbiomes (e.g., gut) has been the subject of extensive optimization,
Chen, Irene A+3 more
core +1 more source
An operator associated with autoregulation of the repressor gene in actinophage øC31 is found in highly conserved copies in intergenic regions in the phage genome [PDF]
Colin J. lngham+4 more
openalex +1 more source