Results 91 to 100 of about 68,311 (200)

Harnessing Large Language Models to Advance Microbiome Research: From Sequence Analysis to Clinical Applications

Advanced Intelligent Discovery, EarlyView.
Large language models are transforming microbiome research by enabling advanced sequence profiling, functional prediction, and association mining across complex datasets. They automate microbial classification and disease‐state recognition, improving cross‐study integration and clinical diagnostics.
Jieqi Xing, He Wang, Yangyang Sun, Xiaoquan Su, Shunyao Wu   +4 more
wiley   +1 more source

Peptide/Antibody–Drug Conjugates for Therapeutic Applications in Inflammatory Disease

Advanced NanoBiomed Research, EarlyView.
Peptide/antibody–drug conjugates (PADCs) combine ligand specificity and cleavable linkers to deliver drugs precisely to disease sites with minimal toxicity. While current approvals focus on oncology, this review examines their untapped potential in inflammatory diseases, detailing mechanisms of targeted delivery and highlighting advances that position ...
Yeongji Jang, Jiwoong Choi, Youngri Ryu, Hyun Kyu Song, Man Kyu Shim, Yoosoo Yang   +5 more
wiley   +1 more source

Targeted treatment of chondrosarcoma with a bacteriophage-based particle delivering a secreted tumor necrosis factor-related apoptosis-inducing ligand

Molecular Therapy: Oncology
Chondrosarcoma (CS) is a malignant cartilage-forming bone tumor that is inherently resistant to chemotherapy and radiotherapy, leaving surgery as the only treatment option.
Aitthiphon Chongchai, Kaoutar Bentayebi, Grace Chu, Wenqing Yan, Sajee Waramit, Thanyaluck Phitak, Prachya Kongtawelert, Peraphan Pothacharoen, Keittisak Suwan, Amin Hajitou   +9 more
doaj   +1 more source

Influence of environmental variables in the efficiency of phage therapy in aquaculture [PDF]

, 2014
Yolanda J. Silva, Liliana Costa, Carla Pereira, Ângela Cunha, Ricardo Calado, Newton C. M. Gomes, Adelaide Almeida   +6 more
openalex   +1 more source

A Call For a Multidisciplinary Future of Phage Therapy to Combat Multi-drug Resistant Bacterial Infections

, 2020
Belinda Loh, Sebastián Leptihn
openalex   +1 more source

Generation of a nanobody against HER2 tyrosine kinase using phage display library screening for HER2-positive breast cancer therapy development [PDF]

, 2021
Thomanai Lamtha, Lueacha Tabtimmai, Kunan Bangphoomi, Duangnapa Kiriwan, Aijaz Ahmad Malik, Wanpen Chaicumpa, Paul M.P. van Bergen en Henegouwen, Kiattawee Choowongkomon   +7 more
openalex   +1 more source

Phage Therapy: Promising For H.pylori Infection

, 2012
Wen Wei Hua Zou
openalex   +1 more source

Generation of Potent Anti-Vascular Endothelial Growth Factor Neutralizing Antibodies from Mouse Phage Display Library for Cancer Therapy [PDF]

, 2016
Yan-Da Lai, Yen-Yu Wu, Yi-Jiue Tsai, Yi-San Tsai, Yuying Lin, Szu‐Liang Lai, Chaoyang Huang, Ying-Yung Lok, Chih-Yung Hu, Jiann-Shiun Lai   +9 more
openalex   +1 more source

Investigating the phenotypic alterations associated with hypermucoviscous hypervirulent Klebsiella pneumoniae during phage resistance development

BMC Microbiology
Phage therapy has been explored and used compassionately in the post-antibiotic era, though phage resistance might pose a serious challenge. The advent of hypervirulent and hypermucoviscous traits in Klebsiella pneumoniae limits therapeutic choices. This
Ramya Juliet, Ramesh Nachimuthu
doaj   +1 more source

Aerosolised Phage Therapy in Combination with Daptomycin for the Treatment of Experimental Ventilator-Associated Pneumonia [PDF]

, 2020
J Prazák, David R. Cameron, Manuela Iten, Luca G. Valente, Stephan M. Jakob, Matthias Hænggi, Stephen L. Leib, Denis Grandgirard, Yok‐Ai Que   +8 more
openalex   +1 more source