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Phage-antibiotic synergy inhibited by temperate and chronic virus competition [PDF]
arXiv, 2021 As antibiotic resistance grows more frequent for common bacterial infections, alternative treatment strategies such as phage therapy have become more widely studied in the medical field. While many studies have explored the efficacy of antibiotics, phage therapy, or synergistic combinations of phages and antibiotics, the impact of virus competition on ...
arxiv
Outside-host phage therapy as a biological control against environmental infectious diseases [PDF]
, 2018 Background: Environmentally growing pathogens present an increasing threat for human health, wildlife and food production. Treating the hosts with antibiotics or parasitic bacteriophages fail to eliminate diseases that grow also in the outside-host ...
Kaitala, Veijo +2 more
core +2 more sources
Frontiers in Microbiology, 2022 The pathogenic Clostridioides difficile and Clostridium perfringens are responsible for many health care-associated infections as well as systemic and enteric diseases. Therefore, they represent a major health threat to both humans and animals.
J. Venhorst +2 more
semanticscholar +1 more source
Frontiers in Immunology, 2022 The appearance of bacteria resistant to most or even all known antibiotics has become a serious medical problem. One such promising and effective alternative form of therapy may be the use of phages, the administration of which is considered to be safe ...
Łukasz Grabowski +3 more
doaj +1 more source
Phage therapy for pulmonary infections: lessons from clinical experiences and key considerations
European Respiratory Review, 2022 Lower respiratory tract infections lead to significant morbidity and mortality. They are increasingly caused by multidrug-resistant pathogens, notably in individuals with cystic fibrosis, hospital-acquired pneumonia and lung transplantation.
G. Mitropoulou +8 more
semanticscholar +1 more source
Results in Chemistry, 2023 Contamination with bacteria and organic matters is becoming a serious challenge for governments and a central issue for public health. Biosynthesized silver nanoparticles (AgNPs) are currently gaining attention due to the additional properties provided ...
Salsabil Makky +10 more
doaj
Antibiotics, 2021 (Background): Multi-drug-resistant Klebsiella pneumoniae (MDR-KP) has steadily grown beyond antibiotic control. Wound infection kills many patients each year, due to the entry of multi-drug resistant (MDR) bacterial pathogens into the skin gaps. However,
Mohamed S. Fayez +8 more
doaj +1 more source
International Journal of Molecular Sciences, 2022 Phage therapy consists of applying bacteriophages, whose natural function is to kill specific bacteria. Bacteriophages are safe, evolve together with their host, and are environmentally friendly. At present, the indiscriminate use of antibiotics and salt
J. L. Villalpando-Aguilar +4 more
semanticscholar +1 more source
Scientific Reports, 2023 The early and rapid detection of pathogenic microorganisms is of critical importance in addressing serious public health issues. Here, a new bacteriophage-based nano-biosensor was constructed and the electrochemical impedimetric method was fully ...
Nader Abdelhamied +3 more
doaj +1 more source
The preclinical and clinical progress of bacteriophages and their lytic enzymes : the parts are easier than the whole [PDF]
, 2019 The therapeutic potential of phages has been considered since their first identification more than a century ago. The evident concept of using a natural predator to treat bacterial infections has, however, since then been challenged considerably ...
Abdelkader, Karim Abdelkader Soufi +4 more
core +1 more source