Results 51 to 60 of about 4,514,314 (397)

The natural dietary genistein boosts bacteriophage-mediated cancer cell killing by improving phage-targeted tumor cell transduction [PDF]

open access: yes, 2016
Gene therapy has long been regarded as a promising treatment for cancer. However, cancer gene therapy is still facing the challenge of targeting gene delivery vectors specifically to tumors when administered via clinically acceptable non-invasive ...
Albahrani, M   +5 more
core   +2 more sources

Phage Therapy for Antibiotic-Resistant Bacterial Infections.

open access: yesAnnual Review of Medicine, 2021
Antibiotic resistance in bacterial pathogens presents a substantial threat to the control of infectious diseases. Development of new classes of antibiotics has slowed in recent years due to pressures of cost and market profitability, and there is a ...
G. Hatfull, R. Dedrick, R. Schooley
semanticscholar   +1 more source

Phage Therapy in a 16-Year-Old Boy with Netherton Syndrome

open access: yesFrontiers in Medicine, 2017
Netherton syndrome (NS) is a rare autosomal recessive disorder, characterized by a classical triad of clinical features, including congenital ichthyosiform erythroderma, trichorrhexis invaginata, and atopic diathesis coupled with frequent bacterial ...
Pikria Zhvania   +4 more
doaj   +1 more source

Bacteriophage as a potential therapy to control antibiotic-resistant Pseudomonas aeruginosa infection through topical application onto a full-thickness wound in a rat model

open access: yesJournal of Genetic Engineering and Biotechnology, 2022
Background Antibiotic-resistant Pseudomonas aeruginosa (P. aeruginosa) is one of the most critical pathogens in wound infections, causing high mortality and morbidity in severe cases.
Nouran Rezk   +9 more
doaj   +1 more source

Characterization of novel bacteriophages for biocontrol of bacterial blight in leek caused by Pseudomonas syringae pv. porri [PDF]

open access: yes, 2016
Pseudomonas syringae pv. porri, the causative agent of bacterial blight in leek (Allium porrum), is increasingly frequent causing problems in leek cultivation. Because of the current lack of control measures, novel bacteriophages were isolated to control
Anneleen eVolckaert   +16 more
core   +3 more sources

Further Considerations on How to Improve Phage Therapy Experimentation, Practice, and Reporting: Pharmacodynamics Perspectives

open access: yesPHAGE, 2022
Phage therapy uses bacterial viruses (bacteriophages) to infect and kill targeted pathogens. Approximately one decade ago, I started publishing on how possibly to improve upon phage therapy experimentation, practice, and reporting.
S. Abedon
semanticscholar   +1 more source

Synergistic Interaction Between Phage Therapy and Antibiotics Clears Pseudomonas Aeruginosa Infection in Endocarditis and Reduces Virulence. [PDF]

open access: yes, 2017
Increasing antibiotic resistance warrants therapeutic alternatives. Here we investigated the efficacy of bacteriophage-therapy (phage) alone or combined with antibiotics against experimental endocarditis (EE) due to Pseudomonas aeruginosa, an archetype ...
Entenza, J.M.   +7 more
core   +1 more source

In Vitro Techniques and Measurements of Phage Characteristics That Are Important for Phage Therapy Success

open access: yesViruses, 2022
Validated methods for phage selection, host range expansion, and lytic activity determination are indispensable for maximizing phage therapy outcomes. In this review, we describe some relevant methods, highlighting their advantages and disadvantages, and
T. Glonti, J. Pirnay
semanticscholar   +1 more source

The Potential of Phage Therapy in Sepsis [PDF]

open access: yesFrontiers in Immunology, 2017
Sepsis remains a difficult clinical challenge, since our understanding of its immunopathology is incomplete and no efficacious treatment currently exists. Its earlier stage results from an uncontrolled inflammatory response to bacteria while in the later stage disturbed immune response with immunodeficiency syndrome develops.
Andrzej Górski   +7 more
openaire   +4 more sources

Bronisława Fejgin (1883–1943): Forgotten Important Contributor to International Microbiology and Phage Therapy

open access: yesAntibiotics, 2021
Bronisława Brandla Fejgin was a Polish-born Jewish female physician. Among Fejgin’s numerous articles in the field of microbiology, her later work was almost entirely devoted to phage research.
Andrzej Grzybowski   +4 more
doaj   +1 more source

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