Results 71 to 80 of about 114,190 (344)
Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents
Advanced Functional Materials, EarlyView.Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras +6 more
wiley +1 more source
Scientific ReportsMetal and metal oxide nanocomposites have unique properties and are promising for antibacterial and anticancer applications. In this work, we aimed to highlight the relationship between the biosynthesis ways of silver and gold-doped zinc oxide ...
Abdallah S. Abdelsattar +3 more
doaj +1 more source
Efficacy of systemic temozolomide‐activated phage‐targeted gene therapy in human glioblastoma
EMBO Molecular Medicine, 2019 Glioblastoma multiforme (GBM) is the most lethal primary intracranial malignant neoplasm in adults and most resistant to treatment. Integration of gene therapy and chemotherapy, chemovirotherapy, has the potential to improve treatment. We have introduced
Justyna Magdalena Przystal +12 more
doaj +1 more source
Advanced Functional Materials, EarlyView.A dual‐layer living hydrogel, ProΦGel, integrates bacteriophages and probiotics for synergistic wound infection therapy. The outer gelatin‐based matrix releases phages on demand in response to P. aeruginosa infections, while inner alginate beads sustain probiotic delivery.
Siyuan Tao +6 more
wiley +1 more source
Viruses, 2015 The development of commercially available transfection reagents for gene transfer applications has revolutionized the field of molecular biology and scientific research.
Amanda Donnelly +4 more
doaj +1 more source
Generation of Lamprey Monoclonal Antibodies (Lampribodies) Using the Phage Display System. [PDF]
, 2019 The variable lymphocyte receptors (VLRs) consist of leucine rich repeats (LRRs) and comprise the humoral antibodies produced by lampreys and hagfishes.
Amemiya, Chris T +3 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.The incorporation of nondigested ECM and synthetic polymers into a co‐electrospinning system enables the decoupling of bioactivity and mechanical properties within a single wrap. This technique is used to develop a multifunctional bone wrap that achieves augmented membrane durability, sustained infection control, and enhanced vascularity for use in ...
Sarah Jones +14 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This study reports an in vivo self‐assembled siRNA strategy that enables the liver to generate small extracellular vesicles (sEVs) tagged with a muscle‐targeting peptide (MSP) and naturally loaded with myostatin (MSTN)‐siRNA. These MSP‐tagged sEVs are systemically delivered to skeletal muscle, efficiently silence MSTN, promote muscle hypertrophy, and ...
Xin Yin +14 more
wiley +1 more source
A proposed integrated approach for the preclinical evaluation of phage therapy in Pseudomonas infections [PDF]
, 2016 Bacteriophage therapy is currently resurging as a potential complement/alternative to antibiotic treatment. However, preclinical evaluation lacks streamlined approaches.
Arabski, Michal +13 more
core +2 more sources
Advanced Healthcare Materials, EarlyView.Thiolated hyaluronic acid (HAMS) synthesized and characterized by NMR, solubility, thiol content, and pKa, is degraded by Staphylococcal hyaluronate lyase but not by mammalian hyaluronidase. Coating polyphosphate–M23 phage endolysin nanoparticles (M23‐PP) with HAMS confers Staphylococcus aureus responsiveness.
Mariana Blanco Massani +11 more
wiley +1 more source