Results 71 to 80 of about 116,257 (347)
Viruses, 2015 The development of commercially available transfection reagents for gene transfer applications has revolutionized the field of molecular biology and scientific research.
Amanda Donnelly +4 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales +11 more
wiley +1 more source
Efficacy of systemic temozolomide‐activated phage‐targeted gene therapy in human glioblastoma
EMBO Molecular Medicine, 2019 Glioblastoma multiforme (GBM) is the most lethal primary intracranial malignant neoplasm in adults and most resistant to treatment. Integration of gene therapy and chemotherapy, chemovirotherapy, has the potential to improve treatment. We have introduced
Justyna Magdalena Przystal +12 more
doaj +1 more source
Are Bordetella bronchiseptica Siphoviruses (Genus Vojvodinavirus) Appropriate for Phage Therapy—Bacterial Allies or Foes? [PDF]
, 2021 Aleksandra Petrović Fabijan +5 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.PCTM microspheres were successfully synthesized using microfluidic and click chemistry techniques.In Vivo and in vitro experiments have shown that PCTM microspheres have obvious targeting, adhesion, membrane penetration and anti‐tumor properties for bladder tumors.The antitumor mechanism of PCTM microspheres is to indirectly induce S‐stage blockage of ...
Zhaoxiang Lu +4 more
wiley +1 more source
A proposed integrated approach for the preclinical evaluation of phage therapy in Pseudomonas infections [PDF]
, 2016 Bacteriophage therapy is currently resurging as a potential complement/alternative to antibiotic treatment. However, preclinical evaluation lacks streamlined approaches.
Arabski, Michal +13 more
core +2 more sources
Directional Liquid Transport Enabled pH‐Responsive Hierarchical Composite for Enhanced Wound Healing
Advanced Healthcare Materials, EarlyView.A hierarchical composite with a gradient architecture transitioning from hydrophobic to hydrophilic layers integrates diode‐like liquid transport, efficient water absorption, breathability, and mechanical robustness. This device enables a multifunctional therapeutic platform with pH‐responsive dual‐drug release, providing synergistic anti‐inflammatory ...
Baolin Wang +5 more
wiley +1 more source
Molecular bases and role of viruses in the human microbiome. [PDF]
, 2014 Viruses are dependent biological entities that interact with the genetic material of most cells on the planet, including the trillions within the human microbiome.
Abeles, Shira R, Pride, David T
core +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Gram-Positive Pneumonia: Possibilities Offered by Phage Therapy [PDF]
, 2021 Lucía Fernández +5 more
openalex +1 more source